New topics of bachelor's theses at IMTM LF UP for the academic year 2021/2022 in the cooperation with CGB laboratories Ostrava, within the project “Analysis of Czech genomes for theranostics” (www.acgt.cz) with the possibility of thesis elaboration and holiday practice in CGB laboratories Ostrava, as
1. Detection of MED12 mutations and selected cytogenetic changes in cervical myomas
Supervisor: MUDr. Josef Srovnal, Ph.D. (IMTM LF UP, josef.srovnal@upol.cz)
Professional supervisor: RNDr. Magdalena Uvirova, Ph.D. (CGB Ostrava, uvirova@pathology.cz)
Number of students: 1
Bachelor training
2. Revision of the variants of unclear significance (VUS) in patients tested for hereditary cancer syndromes in the context of the results of the A-C-G-T project
Supervisor: MUDr. Josef Srovnal, Ph.D. (IMTM LF UP, josef.srovnal@upol.cz)
Professional supervisor: RNDr. Magdalena Uvirova, Ph.D. (CGB Ostrava, uvirova@pathology.cz)
Number of students: 1
Bachelor training
3. Analysis of genetic changes in tumors of prostate cancer patients
Supervisor: MUDr. Josef Srovnal, Ph.D. (IMTM LF UP, josef.srovnal@upol.cz)
Professional supervisor: RNDr. Magdalena Uvirova, Ph.D. (CGB Ostrava, uvirova@pathology.cz)
Number of students: 1
Bachelor training
4. Detection of somatic mutations and selected cytogenetic changes in gliomas
Supervisor: MUDr. Josef Srovnal, Ph.D. (IMTM LF UP, josef.srovnal@upol.cz)
Professional supervisor: RNDr. Magdalena Uvirova, Ph.D. (CGB Ostrava, uvirova@pathology.cz)
Number of students: 1
Bachelor training
Drug synergy studies in 3D spheroids cultures of tumour cell lines
Supervisor: Viswanath Das, PhD (viswanath.das@upol.cz)
Number of student(s): 2
Bachelor training /Master training
Development of organoid assays for anti-tumour drug screening
Supervisor: Viswanath Das, PhD (viswanath.das@upol.cz)
Number of student(s): 2
Bachelor training /Master training
Biochemical and cellular analysis of amyloid staining agents in models of tauopathies and synucleopathies
Supervisor: Viswanath Das, PhD (viswanath.das@upol.cz)
Number of students: 2
Bachelor and Master training
Small animal imaging using microPET/SPECT/CT system in preclinical developement of potential drugs
Supervisor: Mgr. Zbyněk Nový, Ph.D.
Number of students: 1
Bachelor training/ Master training
Lipidomic analysis of exhaled breath condensate
Supervisor: prof. Juan B. De Sanctis, PhD
Number of students: 1
Master training
Antigen presentation and immune response in cancer
Supervisor: prof. Juan B. De Sanctis, PhD
Number of students: 2
Bachelor training
Lipidomics aanalysis of exhaled breath condensate
Supervisor: prof. Juan B. De Sanctis, PhD
Number of students: 1
Bachelor training
Fragment-based de novo design using pharmacophore models
Pavlo Polishchuk, Ph.D.,M.Sc.
Number of students: 1
Master training
Novel 3D pharmacophore representation for machine learning
Pavlo Polishchuk, Ph.D.,M.Sc.
Number of students: 1
Master training
Computationally guided optimization of compound properties
Pavlo Polishchuk, Ph.D.,M.Sc.
Number of students: 1
Master training
Applicability domains in machine learning modeling
Pavlo Polishchuk, Ph.D.,M.Sc.
Number of students: 1
Master training
Genetic biomarkers
prof. Mgr. Jiří Drábek, Ph.D.
Number of students: 1
Master training
Epigenetic biomarkers
prof. Mgr. Jiří Drábek, Ph.D.
Number of students: 1
Master training
Identification of small molecule cell cycle modulators
Mgr. Jiří Řehulka, Ph.D.
Number of students: 0
Bachelor training/ Master training