Laboratory of Experimental Medicine

The Laboratory of Experimental Medicine (LEM) was established in 1998 at the Department of Pediatrics, Faculty of Medicine and DentistryPalacky University and University Hospital in Olomouc. Later in 2010, the LEM became a moving force in building-up and establishment of the Institute of Molecular and Translational Medicine. 

Our researchers are organized to research groups and perform molecular, cellular and integrative research at the highest international level and to train a new generation of successful scientists. We study biological processes that govern normal and pathological human bodily functions that are involved in disease pathogenesis. Albeit our research is disease agnostic, most of our expertise relates to cancer, inflammation, infection, rare diseases and neurodegeneration. Our spectrum of research ranges from basic and translational science, including research and development of small molecules, radiopharmaceutics, identification of new therapeutic targets, drug repurposing, first use of molecules in man (Phase I trials), biomarker identification and validation trials, development of in vitro diagnostics, through to real-world evidence studies using routinely collected data.Several of our research environments have been recognized as outstanding both at the national and European levels. We also strive to stimulate our young researchers with our enthusiasm for research and wish to increase their interest in both basic and applied sciences. We expose them to the most up-to-date science, cutting edge technologies and prepare them for lifelong learning in their future careers. 

Our research interests and domains include: Research and development of small molecules and biologics for innovative therapies; Imaging and tracing of human diseases, development of radiopharmaceutics; Identification and validation diagnostic, prognostic and predictive biomarkers to advance early disease diagnostics and personalized medicine; Better understanding disease complexity employing multidimensional -omic techniques (proteomics, genomics, transcriptomics, metabolomics, lipidomics, cellulomics, etc.); Advancing high-throughput biology and screening techniques in medical research; Research on translational in vitro and in vivo models (e.g. organoids, patient-derived xenografts, induced pluripotent stem cells); Development of information technologies, including the artificial intelligence, and solutions to support data stewardship in biomedical domain; Advancing nanotechnologies for treatment and detection of human disorders; Proof-of-concept preclinical and early clinical trials.
YANG, C., L. POSTOVA SLAVETINSKA, M. FLEUTI, B. KLEPETAROVA, M. TICHÝ, S. GURSKÁ, P. PAVLIŠ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C-H Dibenzothiophenation and Negishi Coupling. Journal of the American Chemical Society. 2022, 144(42), 19437-19446, ISSN 0002-7863, IF: 16.383, PMID: 36245092
REISSIG, F., K. ZACHSLER, Z. NOVÝ, M. PETŘÍK, K. BENDOVÁ, D. KURFÜRSTOVÁ, J. BOUCHAL, M. ĹUDIK, F. BRANDT, K. KOPKA, M. KHOYLOU, H.J. PIETZSCH, M. HAJDÚCH a C. MAMAT. Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin. Theranostics. 2022, 12(17), 7203-7215, ISSN 1838-7640, IF: 11.6, PMID: 36438496
KVAKOVA, K., M. ONDRA, J. SCHIMER, M. PETŘÍK, Z. NOVÝ, H. RAABOVA, M. HAJDÚCH a P. CIGLER. Visualization of Sentinel Lymph Nodes with Mannosylated Fluorescent Nanodiamonds. Advanced Functional Materials. 2022, 32(23), 2109960, ISSN 1616-301X, IF: 18.808,
XIAO, W., L. FANG, Y. ZHAO, J. LACK, M. GUAN, B. ZHU, E. JAEGER, L. KERRIGAN, T. BLOMQUIST, T. HUNG, M. SULTAN, K. IDLER, A. SCHERER, R. KUSKO, M. MOOS, C. XIAO, S. SHERRY, O. ABAAN, W. CHEN, X. CHEN, J. NORDLUND, U. LILJEDAHL, R. MAESTRO, M. POLANO, J. DRÁBEK, P. VOJTA, S. KOKS, E. REIMANN, B. MADALA, T. MERCER, C. MILLER, H. JACOB, T. TRUONG, A. MOSHREFI, A. NATARAJAN, A. GRANAT, G. SCHROTH, R. KALAMEGHAM, E. PETERS, V. PETITJEAN, A. WALTON, T. SHEN, K. TALSANIA, C. VERA, K. LANGEBACH, M. DE MARS, J. HIPP, J. WILLEY, J. WANG, J. SHETTY, Y. KRIGA, A. RAZIUDDIN, B. TRAN, Y. ZHENG, Y. YU, M. CAM, P. JAILWALA, C. NGUYEN, D. MEERZAMAN, Q. CHEN, B. ERNEST, U. MEHRA, R. JENSEN, W. JONES, J. LI, B. PAPAS, M. PIROOZNIA, Y. CHEN, F. SEIFUDDIN, Z. LI, X. LIU, W. RESCH, J. WANG, L. WU, G. YAVAS, C. MILES, B. NING, W. TONG, C. MASON, E. DONALDSON, S. LABABIDI, L. STAUDT, Z. TEZAK, H. HONG a C. WANG. Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing. Nature Biotechnology. 2021, 39(9), 1141-50, ISSN 1087-0156, IF: 54.908, PMID: 34504346
ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199, ISSN 0028-0836, IF: 40.137, PMID: 29211715

Impact Factor Journals

STEJSKAL, P., H. GODARZI, J. SROVNAL, M. HAJDÚCH, L. VAN ´T VEER a M. MAGBUNUA. Circulating tumor nucleic acids: biology, release mechanisms, and clinical relevance. Molecular Cancer. 2023, 22(1), 15, ISSN 1476-4598, IF: 41.444, PMID: 36681803
OŽDIAN, T., J. VODICKA, J. DOSTÁL, D. HOLUB, J. VÁCLAVKOVÁ, M. JESETA, B. HAMERNÍKOVÁ, P. KOUŘILOVÁ, O. MALCHAR, V. DVORAK, P. HEJTMANEK, K. SOBKOVA, P. VENTRUBA, R. PILKA, P. DŽUBÁK a M. HAJDÚCH. Proteome Mapping of Cervical Mucus and Its Potential as a Source of Biomarkers in Female Tract Disorders. International Journal of Molecular Sciences. 2023, 24(2), 1038, ISSN 1422-0067, IF: 6.208, PMID: 36674559
GARMENDIA, J., A. GARCIA, C.V. DE SANTCTIS, M. HAJDÚCH a J.B. DE SANCTIS. Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19. Current Issues in Molecular Biology. 2023, 45(1), 33-50, ISSN 1467-3037, IF: 2.976, PMID: 36661489
JURÁŠEK, M., J. ŘEHULKA, L. HRUBÁ, A. IVANOVA (NIKONENKO), S. GURSKÁ, O. MOKSHYNA, P. TROUSIL, K. HUML, P. POLISHCHUK, M. HAJDÚCH, P. DRAŠAR a P. DŽUBÁK. Triazole-based estradiol dimers prepared via CuAAC from 17α-ethinyl estradiol with five-atom linkers causing G2/M arrest and tubulin inhibition. Bioorganic Chemistry. 2023, 131(2023), 106334, ISSN 0045-2068, IF: 5.307, PMID: 36592487
KVASNIČKA, A., L. NAJDEKR, D. DOBEŠOVÁ, B. PISKLÁKOVÁ, E. IVANOVOVÁ a D. FRIEDECKÝ. Clinical lipidomics in the era of the big data. Clinical Chemistry and Laboratory Medicine. 2023, -, -, ISSN 1434-6621 , IF: 8.490, PMID: 36592414
BOUŠKA, O., H. JAWOREK, V. KOUDELÁKOVÁ, K. KUBÁŇOVÁ, P. DŽUBÁK, R. SLAVKOVSKÝ, B. ŠIŠKA, P. PAVLIŠ, J. VRBKOVÁ a M. HAJDÚCH. Evaluation of Non-Invasive Gargle Lavage Sampling for the Detection of SARS-CoV-2 Using rRT-PCR or Antigen Assay. Viruses. 2022, 14(12), 2829, ISSN 1999-4915, IF: 5.818, PMID: 36560833
ALIMAJSTOROVIC, Z., S. MOLLAN, O. GRECH, J. MITCHELL, A. YIANGOU, M. THALLER, H. LYONS, M. SASSANI, S. SENEVIRATNE, T. HANCOX, A. JANKEVICS, L. NAJDEKR, W. DUNN a A. SINCLAIR. Dysregulation of Amino Acid, Lipid, and Acylpyruvate Metabolism in Idiopathic Intracranial Hypertension: A Non-targeted Case Control and Longitudinal Metabolomic Study. Journal of Proteome Research. 2022, -, -, ISSN 1535-3893, IF: 5.370, PMID: 36534069
REISSIG, F., K. ZACHSLER, Z. NOVÝ, M. PETŘÍK, K. BENDOVÁ, D. KURFÜRSTOVÁ, J. BOUCHAL, M. ĹUDIK, F. BRANDT, K. KOPKA, M. KHOYLOU, H.J. PIETZSCH, M. HAJDÚCH a C. MAMAT. Modulating the pharmacokinetic profile of Actinium-225-labeled macropa-derived radioconjugates by dual targeting of PSMA and albumin. Theranostics. 2022, 12(17), 7203-7215, ISSN 1838-7640, IF: 11.6, PMID: 36438496
VIDLAŘOVÁ, M., E. BERTA, P. PRASIL, A. PROKOPOVÁ, S. GURSKÁ, M. KHOYLOU, A. ŘEHULKOVÁ, P. KOUŘILOVÁ, J. CHUDÁČEK, M. SZKORUPA, J. KLEIN, J. ŠKARDA, J. SROVNAL a M. HAJDÚCH. Cannabinoid receptor 2 expression in early-stage non-small cell lung cancers identifies patients with good prognosis and longer survival. Translational Lung Cancer Research. 2022, 11(10), 2040-2050, ISSN 2218-6751, IF: 4.726, PMID: 36386452
OLDONI, E., G. SAUNDERS, F. BIETRIX, M. BERMEJO, A. NIEHUES, P. ´T HOEN, J. NORDLUND, M. HAJDÚCH, A. SCHERER, L. KOZERA, M. ESTELLER, L. SHI, A.E. USSI, A. ANDREU a A. VAN GOOL. Tackling the translational challenges of multi-omics research in the realm of European personalised medicine: A workshop report. Frontiers in Molecular Biosciences. 2022, 9, 974799, ISSN 2296-889X, IF: 6.113, PMID: 36310597
BARUCIC, D., S. KAUSHIK, J. KYBIC, J. STANKOVÁ, P. DŽUBÁK a M. HAJDÚCH. Characterization of drug effects on cell cultures from phase-contrast microscopy images. Computers in Biology and Medicine. 2022, 151, 106171, ISSN 0010-4825, IF: 6.698, PMID: 36306582
GUTIERREZ, J., E. FERNANDEZ-MOREIRA, M. RODRIGUEZ, M. MIJARES, J.B. DE SANCTIS, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, J. BRUNO-COMENAREZ, L. ROJAS, D. DEFFIUX, L. POUYSEGU, S. QUIDEAU, J. CHARRIS a H. RAMIREZ. Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage. Pharmaceuticals. 2022, 15(10), 1234, ISSN 1424-8247, IF: 5.215, PMID: 36297346
BORKOVÁ, L., I. FRYDRYCH, B. VRÁNOVÁ, N. JAKUBCOVÁ, B. LIŠKOVÁ, P. DŽUBÁK, P. PAVLIŠ, M. HAJDÚCH a M. URBAN. Lupane derivatives containing various aryl substituents in the position 3 have selective cytostatic effect in leukemic cancer cells including resistant phenotypes. European Journal of Medicinal Chemistry. 2022, 244, 114850, ISSN 0223-5234, IF: 7.088, PMID: 36283179
YANG, C., L. POSTOVA SLAVETINSKA, M. FLEUTI, B. KLEPETAROVA, M. TICHÝ, S. GURSKÁ, P. PAVLIŠ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis of Polycyclic Hetero-Fused 7-Deazapurine Heterocycles and Nucleosides through C-H Dibenzothiophenation and Negishi Coupling. Journal of the American Chemical Society. 2022, 144(42), 19437-19446, ISSN 0002-7863, IF: 16.383, PMID: 36245092
BARTA, P., R. KAMARAJ, M. KUCHAROVA, Z. NOVÝ, M. PETŘÍK, K. BENDOVÁ, M. HAJDÚCH, P. PÁVEK a F. TREJTNAR. Preparation, In Vitro Affinity, and In Vivo Biodistribution of Receptor-Specific 68Ga-Labeled Peptides Targeting Vascular Endothelial Growth Factor Receptors. Bioconjugate Chemistry. 2022, 33(10), 1825-1836, ISSN 1043-1802, IF: 6.069, PMID: 36197842
HODOŇ, J., I. FRYDRYCH, Z. TRHLÍKOVÁ, J. POKORNÝ, L. BORKOVÁ, S. BENICKÁ, M. VLK, B. LIŠKOVÁ, A. KUBÍČKOVÁ, M. MEDVEDÍKOVÁ, M. PISÁR, J. ŠAREK, V. DAS, A. LIGASOVÁ, K. KOBERNA, P. DŽUBÁK, M. HAJDÚCH a M. URBAN. Triterpenoid pyrazines and pyridines - Synthesis, cytotoxicity, mechanism of action, preparation of prodrugs. European Journal of Medicinal Chemistry. 2022, 243, 114777, ISSN 0223-5234, IF: 7.088, PMID: 36174412
VRZALOVA, A., P. PECINKOVA, S. GURSKÁ, P. DŽUBÁK, M. SZOTKOWSKI, M. HAJDÚCH, S. MANI a Z. DVORAK. Mixture Effects of Tryptophan Intestinal Microbial Metabolites on Aryl Hydrocarbon Receptor Activity. International Journal of Molecular Sciences. 2022, 23(18), 10825, ISSN 1422-0067, IF: 6.208, PMID: 36142735
HORGAN, D., M. HAJDÚCH, M. VRANA, J. SODERBERG, N. HUGHES, M. OMAR, J. LAL, M. KOZARIC, F. CASCINI, V. THALER, O. SOLA-MORALES, M. ROMAO, F. DESTREBECQ a E. GROSS. European Health Data Space-An Opportunity Now to Grasp the Future of Data-Driven Healthcare. Healthcare. 2022, 10(9), 1629, ISSN 2227-9032, IF: 3.160, PMID: 36141241
ŘEHULKA, J., I. SUBTELNA, A.. KRYSHCHYSHYN-DYLEVYCH, A. CHERNIIENKO, A.S. IVANOVA, M. MATVEIEVA, P. POLISHCHUK, S. GURSKÁ, M. HAJDÚCH, O. ZAGRIJTCHUK, P. DŽUBÁK a R. LESYK. Anticancer 5-arylidene-2-(4-hydroxyphenyl)aminothiazol-4(5H)-ones as tubulin inhibitors. Archiv der Pharmazie. 2022, 355(12), e2200419, ISSN 0365-6233 , IF: 4.613, PMID: 36109178
BLANCO, Z., E. FERNANDEZ-MOREIRA, M. MIJARES, C. CELIS, G. MARTINEZ, J.B. DE SANCTIS, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, A. MIJOBA, Y. GARCIA, X. SERRANO, N. HERRERA, J. CORREA-ABRIL, Y. PARRA, J. ANGEL, H. RAMIREZ a J. CHARRIS. Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2 H)-one Derivatives. Molecules. 2022, 27(17), 5626, ISSN 1420-3049, IF: 4.927, PMID: 36080388
SMEŠNÝ TRTKOVÁ, K., P. LUŽNÁ, D. WEISER DROZDKOVA, K. ČÍŽKOVÁ, L. JANOVSKA, J. GURSKÝ, D. PRUKOVA, I. FRYDRYCH, M. HAJDÚCH a J. MINARIK. The epigenetic impact of suberohydroxamic acid and 5‑Aza‑2'‑deoxycytidine on DNMT3B expression in myeloma cell lines differing in IL‑6 expression. Molecular Medicine Reports. 2022, 26(4), 321, ISSN 1791-2997, IF: 3.423, PMID: 36043519
SCHADICH, E., S. NYLEN, S. GURSKÁ, J. KOTULOVÁ, S. ANDRONATI, V. PAVLOVSKY, S. SOBOLEVA, P. POLISHCHUK, M. HAJDÚCH a P. DŽUBÁK. Activity of 1-aryl-4-(naphthalimidoalkyl) piperazine derivatives against Leishmania major and Leishmania mexicana. Parasitology International. 2022, 91, 102647, ISSN 1383-5769, IF: 2.106, PMID: 35985636
KLOS, D., M. DUŠEK, E. SAMOLOVA, M. ZATLOUKAL, V. NOZKOVA, N. NESNAS, L. PLACKOVA, R. KOPRNA, Z. SPISEK, H. VYLICILOVA, O. PLIHAL, K. DOLEZAL, J. VOLLER, A. KADLECOVA, A. STRNAD a L. PLÍHALOVÁ. Correction to New Water-Soluble Cytokinin Derivatives and Their Beneficial Impact on Barley Yield and Photosynthesis. Journal of Agricultural and Food Chemistry. 2022, 70(33), 10383-10384, ISSN 0021-8561, IF: 5.895, PMID: 35950894
GIUSTO, E., L. ŽÁRSKÁ, D. BEIRNE, A. ROSSI, G. BASSI, A. RUFFINI, M. MONTESI, D. MONTAGNER, V. RANC a G. PANSERI. Graphene Oxide Nanoplatforms to Enhance Cisplatin-Based Drug Delivery in Anticancer Therapy. Nanomaterials. 2022, 12(14), 2372, ISSN 2079-4991, IF: 5.719, PMID: 35889596
KUBÍČKOVÁ, A., Z. MACEČKOVÁ, P. VOJTA, M. ONDRA, J. VOLEJNÍKOVÁ, P. KOŘALKOVÁ, A. JUNGOVA, O. JAHODA, R. MOJZIKOVA, I. HADAČOVÁ, J. CERMAK, M. HORVÁTHOVÁ, D. POSPÍŠILOVÁ a M. HAJDÚCH. Missense mutation in RPS7 causes Diamond-Blackfan anemia via alteration of erythrocyte metabolism, protein translation and induction of ribosomal stress. Blood Cells, Molecules & Diseases. 2022, 97, 102690, ISSN 1079-9796, IF: 2.372, PMID: 35871033
NAVARRO, C., A. ORTEGA, R. SANTELIZ, B. GARRIDO, M. CHACIN, N. GALBAN, I. VERA, J.B. DE SANCTIS a V. BERMUDEZ. Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches. Pharmaceutics. 2022, 14(6), 1303, ISSN 1999-4923 , IF: 6.525, PMID: 35745875
KLOS, D., M. DUŠEK, E. SAMOLOVA, M. ZATLOUKAL, V. NOZKOVA, N. NESNAS, L. PLACKOVA, R. KOPRNA, Z. SPISEK, H. VYLICILOVA, O. PLIHAL, K. DOLEZAL, J. VOLLER, A. KADLECOVA, M. STRNAD a L. PLÍHALOVÁ. New Water-Soluble Cytokinin Derivatives and Their Beneficial Impact on Barley Yield and Photosynthesis. Journal of Agricultural and Food Chemistry. 2022, 70(23), 7288-7301, ISSN 0021-8561, IF: 5.279, PMID: 35658447
PURIS, E., ?. KOUŘIL, L. NAJDEKR, S. AURIOLA, S. LOPPI, P. KORHONEN, M. GOMEZ-BUDIA, G. FRICKER, K. KANNINEN, T. MALM, D. FRIEDECKÝ a M. GYNTHER. Metabolomic, lipidomic and proteomic characterisation of lipopolysaccharide-induced inflammation mouse model. Neuroscience. 2022, 496, 165-178, ISSN 0306-4522, IF: 3.590, PMID: 35636730
ANNADURAI, N., L. MALINA, J. MALOHLAVA, M. HAJDÚCH a V. DAS. Tau R2 and R3 are essential regions for tau aggregation, seeding and propagation. Biochimie. 2022, 200, 79-86, ISSN 0300-9084, IF: 4.079, PMID: 35623497
DE SANCTIS, J.B., J. CHARRIS, Z. BLANCO, H. RAMIREZ, G. MARTINEZ a M. MIJARES. chybi pdf a dedi_Molecular Mechanisms of Chloroquine and Hydroxychloroquine use in Cancer Therapy. Anti-cancer Agents in Medicinal Chemistry. 2022, -, -, ISSN 1871-5206, IF: 2.507, PMID: 35598250
ZELJKOVIC, S., E. SCHADICH, P. DŽUBÁK, M. HAJDÚCH a P. TARKOWSKI. Antiviral Activity of Selected Lamiaceae Essential Oils and Their Monoterpenes Against SARS-Cov-2. Frontiers in Pharmacology. 2022, 13, 893634, ISSN 1663-9812, IF: 5.811, PMID: 35586050
SLAVÍK, H., V. BALIK, F. KOKAS, R. SLAVKOVSKÝ, J. VRBKOVÁ, A. ŘEHULKOVÁ, T. LAUSOVÁ, J. EHRMANN, S. GURSKÁ, I. ÜBERALL, M. HAJDÚCH a J. SROVNAL. Transcriptomic Profiling Revealed Lnc-GOLGA6A-1 as a Novel Prognostic Biomarker of Meningioma Recurrence. Neurosurgery. 2022, 91(2), 360-369, ISSN 0148-396X , IF: 4.654, PMID: 35551164
KUDLOVÁ, N., J.B. DE SANCTIS a M. HAJDÚCH. Cellular Senescence: Molecular Targets, Biomarkers, and Senolytic Drugs. International Journal of Molecular Sciences. 2022, 23(8), 4168, ISSN 1422-0067, IF: 5.924, PMID: 35456986
PAUN, R., D. DUMUT, A. CENTORAME, T. THURAISINGAM, M. HAJDÚCH, M. MISTRÍK, P. DŽUBÁK, J.B. DE SANCTIS, D. RADZIOCH a M. TABRIZIAN. One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy. Pharmaceutics. 2022, 14(3), 640, ISSN 1999-4923, IF: 6.321, PMID: 35336014
SALAZAR, J., D. PIRELLA, M. NAVA, A. CASTRO, L. ANGARITA, H. PARRA, S. DURAN-AGUERO, D. ROJAS-GOMEZ, N. GALBAN, R. ANEZ, M. CHACIN, A. DIAZ, N. VILASMIL, J.B. DE SANCTIS a V. BERMUDEZ. Specialized Proresolving Lipid Mediators: A Potential Therapeutic Target for Atherosclerosis. International Journal of Molecular Sciences. 2022, 23, 3133, ISSN 1422-0067, IF: 5.924, PMID: 35328553
ŠPORIKOVÁ , Z., R. SLAVKOVSKÝ, L. TUČKOVÁ, O. KALITA, M. HOUDOVÁ MEGOVÁ , J. EHRMANN, M. HAJDÚCH, L. HRABALEK a M. VAVERKA. IDH1/2 Mutations in Patients With Diffuse Gliomas. Applied Immunohistochemistry and Molecular Morphology. 2021, 30(3), 178-183, ISSN 1541-2016, IF: 2.085, PMID: 35262523
MACEČKOVÁ, Z., A. KUBÍČKOVÁ, J.B. DE SANCTIS a M. HAJDÚCH. Effect of Glucocorticosteroids in Diamond-Blackfan Anaemia: Maybe Not as Elusive as It Seems. International Journal of Molecular Sciences. 2022, 8(23), 3, ISSN 1422-0067, IF: 5.924, PMID: 35163808
SPURNA, Z., Z. CAPKOVA, J. SROVNAL, J. DUCHOSLAVOVÁ, L. PUNOVA, D. ALEKSIJEVIC a R. VRTEL. Clinical impact of variants in non-coding regions of SHOX - current knowledge. Gene. 2022, 818, 146238, ISSN 0378-1119, IF: 3.688, PMID: 35074420
KOTULOVÁ, J., K. LÓNOVÁ, A. KUBÍČKOVÁ, J. VRBKOVÁ, P. KOUŘILOVÁ, M. HAJDÚCH a P. DŽUBÁK. 2‑Cl‑IB‑MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines. International Journal of Molecular Medicine. 2022, 49(3), 31, ISSN 1107-3756, IF: 4.101, PMID: 35039871
ORTEGA, A., I. VERA, M.P. DÍAZ, C. NAVARRO, M. ROJAS, W. TORRES, H. PARRA, J. SALAZAR, J.B. DE SANCTIS a V. BERMUDEZ. The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises. Molecular Sciences. 2021, 23(1), 430, ISSN 1422-0067, IF: 5.924, PMID: 35008857
HRUBÁ, L., P. POLISHCHUK, V. DAS, M. HAJDÚCH a P. DŽUBÁK. An identification of MARK inhibitors using high throughput MALDI-TOF mass spectrometry. Biomedicine & Pharmacotherapy. 2022, 146, 112549, ISSN 0753-3322, IF: 6.530, PMID: 34923338
SLAVKOVSKÝ, R., J. STRÁNSKÁ, V. VĚNSKOVÁ, S. JANČÍK, L. KOTKOVÁ, P. VOJTA, P. FLODR, M. BARTOUŠKOVÁ, H. ŠTUDENTOVÁ, M. HAJDÚCH a J. DRÁBEK. Development and extensive analytical validation of deep amplicon sequencing for detecting KRAS and NRAS mutations in metastatic colorectal cancer samples. Neoplasma. 2021, 69(1), 203-2015, ISSN 0028-2685, IF: 2.575, PMID: 34881628
KUDLOVÁ, N., H. SLAVÍK, P. DUŠKOVÁ, T. FÜRST, J. SROVNAL, J. BÁRTEK, M. MISTRÍK a M. HAJDÚCH. An efficient, non-invasive approach for in-vivo sampling of hair follicles: design and applications in monitoring DNA damage and aging. Aging. 2021, 13(23), 25004-25024, ISSN 1945-4589, IF: 5.682, PMID: 34874896
DE SANCTIS, J.B. Assessment of Inflammatory Response and its Resolution in Viral Infection and Rheumatoid Arthritis. Current Pharmaceutical Design. 2021, 27(44), 4433, ISSN 1381-6128, IF: 3.116, PMID: 34844530
KOTULOVÁ, J., M. HAJDÚCH a P. DŽUBÁK. Current Adenosinergic Therapies: What Do Cancer Cells Stand to Gain and Lose?. International Journal of Molecular Sciences. 2021, 22(22), 12569, ISSN 1422-0067, IF: 5.924, PMID: 34830449
RAFFAELE, M., K. KOVACOVICOVA, T. BIAGINI, O. LO RE, J. FROHLICH, S. GIALLONGO, J. NHAN, A. GIANNONE, D. CABIBI, M. IVANOV, A. TONCHEV, M. MISTRÍK, M. LACEY, P. DŽUBÁK, S. GURSKÁ, M. HAJDÚCH, J. BÁRTEK, T. MAZZA, V. MICALE, S. CURRAN a M. VINCIGUERRA. Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects. Geroscience. 2021, 44(1), 463-483, ISSN 2509-2715, IF: 7.713, PMID: 34820764
ZHAO, Y., L. FANG, T. SHEN, S. CHOUDHARI, K. TALSANIA, X. CHEN, J. SHETTY, Y. KRIGA, B. TRAN, B. ZHU, Z. CHEN, W. CHEN, C. WANG, E. JAEGER, D. MEERZAMAN, C. LU, K. IDLER, L. REN, Y. ZHENG, L. SHI, V. PETITJEAN, M. SULTAN, T. HUNG, E. PETERS, J. DRÁBEK, P. VOJTA, R. MAESTRO, D. GASPAROTTO, S. KOKS, E. REIMANN, A. SCHERER, J. NORDLUND, U. LIJEDAHL, J. FOOX, C. MASON, C. XIAO, H. HONG a W. XIAO. Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study. Scientific Data. 2021, 8(1), 296, ISSN 2052-4463, IF: 6.444, PMID: 34753956
ANNADURAI, N., L. MALINA, M. SALMONA, L. DIOMEDE, A. BASTONE, A. CAGNOTTO, M. ROMEO, M. SREJBER, K. BERKA, M. OTYEPKA, M. HAJDÚCH a V. DAS. Antitumour drugs targeting tau R3 VQIVYK and Cys322 prevent seeding of endogenous tau aggregates by exogenous seeds. FEBS Journal. 2021, 289(7), 1929-1949, ISSN 1742-464X, IF: 5.542, PMID: 34743390
LIGASOVÁ, A., I. ROSENBERG, M. BOCKOVA, J. HOMOLA a K. KOBERNA. Anchored linear oligonucleotides: the effective tool for the real-time measurement of uracil DNA glycosylase activity. Open Biology. 2021, 11(10), 200136, ISSN 2046-2441, IF: 6.411, PMID: 34665968
LIGASOVÁ, A. a K. KOBERNA. Strengths and Weaknesses of Cell Synchronization Protocols Based on Inhibition of DNA Synthesis. International Journal of Molecular Sciences. 2021, 22(19), 10759, ISSN 1422-0067, IF: 5.924, PMID: 34639098
CHAVEZ-CASTILLO, M., A. ORTEGA, L. CUDRIS-TORRES, M. ROJAS, A. MANZANO, B. GARRIDO, J. SALAZAR, A. SILVA, D. ROJAS-GOMEZ, J.B. DE SANCTIS a V. BERMUDEZ. Specialized Pro-Resolving Lipid Mediators: The Future of Chronic Pain Therapy?. International Journal of Molecular Sciences. 2021, 22(19), 10370, ISSN 1422-0067, IF: 5.923, PMID: 34638711
BUCHTOVÁ, T., Z. ŠKROTT, K. CHROMÁ, J. ŘEHULKA, P. DŽUBÁK, M. HAJDÚCH, D.. LUKÁČ, S. ARAMPATZIS, J. BÁRTEK a M. MISTRÍK. Cannabidiol-induced activation of the metallothionein pathway impedes anticancer effects of disulfiram and its metabolite CuET. Molecular Oncology. 2021, 16(7), 1541-1554, ISSN 1574-7891, IF: 6.603, PMID: 34632694
JAWOREK, H., V. KOUDELÁKOVÁ, I. OBORNA, B. ZBORILOVA, J. BREZINOVA, D. RUZICKOVA, J. VRBKOVÁ, P. KOUŘILOVÁ a M. HAJDÚCH. Impact of human papillomavirus infection on semen parameters and reproductive outcomes. Reproductive biology and endocrinology. 2021, 19(1), 156, ISSN 1477-7827, IF: 5.211, PMID: 34627284
LIGASOVÁ, A. a K. KOBERNA. DNA Dyes—Highly Sensitive Reporters of Cell Quantification: Comparison with Other Cell Quantification Methods. Molecules. 2021, 26(18), 5515, ISSN 1420-3049, IF: 4.411, PMID: 34576986
MISSLINGER, M., M. PETŘÍK, J. PFISTER, I. HUBMANN, K. BENDOVÁ, C. DECRISTOFORO a H. HAAS. Desferrioxamine B-Mediated Pre-Clinical In Vivo Imaging of Infection by the Mold Fungus Aspergillus fumigatus. Journal of Fungi. 2021, 7(9), 734, ISSN 2309-608X, IF: 6.499, PMID: 34575772
DOBIAS, R., A. SKRIBA, T. PLUHACEK, M. PETŘÍK, A. PALYZOVA, M. KANOVA, E. CUBOVA, J. HOUST, J. NOVAK, D. STEVENS, G. MITULOVIC, E. KREJCI, P. HUBACEK a V. HAVLICEK. Noninvasive Combined Diagnosis and Monitoring of Aspergillus and Pseudomonas Infections: Proof of Concept. Journal of Fungi. 2021, 7(9), 730, ISSN 2309-608X, IF: 6.499, PMID: 34575768
KODR, D., J. STANKOVÁ, M. RUMLOVA, P. DŽUBÁK, J. ŘEHULKA, T. ZIMMERMANN, I. KRIZOVA, S. GURSKÁ, M. HAJDÚCH, P. DRAŠAR a M. JURÁŠEK. Betulinic Acid Decorated with Polar Groups and Blue Emitting BODIPY Dye: Synthesis, Cytotoxicity, Cell-Cycle Analysis and Anti-HIV Profiling. Biomedicines. 2021, 9(9), 1104, ISSN 2227-9059, IF: 6.081, PMID: 34572290
ZANKOV, D., M. MATVEIEVA, A. IVANOVA (NIKONENKO), R. NUGMANOV, I. BASKIN, A. VARNEK, P. POLISHCHUK a T. MADZHIDOV. QSAR Modeling Based on Conformation Ensembles Using a Multi-Instance Learning Approach. Journal of Chemical Information and Modeling. 2021, 61(10), 4913-4923, ISSN 1549-9596, IF: 4.956, PMID: 34554736
FANG, L., B. ZHU, Y. ZHAO, W. CHEN, Z. YANG, L. KERRIGAN, K. LANGEBACH, M. DE MARS, K. IDLER, H. JACOB, Y. ZHENG, Y. YU, E. JAEGER, G. SCHROTH, O. ABAAN, K. TALSANIA, J. LACK, T. SHEN, S. STANBOULY, B. TRAN, J. SHETTY, Y. KRIGA, D. MEERZAMAN, C. NGUYEN, V. PETITJEAN, M. SULTAN, M. CAM, M. MEHTA, T. HUNG, E. PETERS, R. KALAMEGHAM, S. SAHRAEIAN, M. MOHIYUDDI, T. GUO, L. YAO, L.A. SONG, H. LAM, J. DRÁBEK, P. VOJTA, R. MAESTRO, D. GASPAROTTO, S. KOKS, E. REIMANN, A. SCHERER, J. NORDLUND, U. LILJEDAHL, R. JENSEN, M. PIROOZNIA, Z. LI, C. XIAO, S. SHERRY, R. KUSKO, M. MOOS, E. DONALDSON, Z. TEZAK, B. NING, W. TONG, J. LI, P. DUERKEN-HUGHES, C. CATALANOTTI, S. MAHESHWARI, J. SHUGA, W. LIANG, J. KEATS, J. ADKINS, E. TASSONE, V. ZISMANN, T. MCDANIEL, J. TRENT, J. FOOX, D. BUTLER, C. MASON, H. HONG, C. WANG, W. XIAO a I. SOMATIC MUTATION WORKING GROUP OF SEQUENCING QUALITY CONTROL PHASE II CONSORTIUM. Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing. Nature Biotechnology. 2021, 39(9), 1151-60, ISSN 1087-0156, IF: 54.908, PMID: 34504347
XIAO, W., L. FANG, Y. ZHAO, J. LACK, M. GUAN, B. ZHU, E. JAEGER, L. KERRIGAN, T. BLOMQUIST, T. HUNG, M. SULTAN, K. IDLER, A. SCHERER, R. KUSKO, M. MOOS, C. XIAO, S. SHERRY, O. ABAAN, W. CHEN, X. CHEN, J. NORDLUND, U. LILJEDAHL, R. MAESTRO, M. POLANO, J. DRÁBEK, P. VOJTA, S. KOKS, E. REIMANN, B. MADALA, T. MERCER, C. MILLER, H. JACOB, T. TRUONG, A. MOSHREFI, A. NATARAJAN, A. GRANAT, G. SCHROTH, R. KALAMEGHAM, E. PETERS, V. PETITJEAN, A. WALTON, T. SHEN, K. TALSANIA, C. VERA, K. LANGEBACH, M. DE MARS, J. HIPP, J. WILLEY, J. WANG, J. SHETTY, Y. KRIGA, A. RAZIUDDIN, B. TRAN, Y. ZHENG, Y. YU, M. CAM, P. JAILWALA, C. NGUYEN, D. MEERZAMAN, Q. CHEN, B. ERNEST, U. MEHRA, R. JENSEN, W. JONES, J. LI, B. PAPAS, M. PIROOZNIA, Y. CHEN, F. SEIFUDDIN, Z. LI, X. LIU, W. RESCH, J. WANG, L. WU, G. YAVAS, C. MILES, B. NING, W. TONG, C. MASON, E. DONALDSON, S. LABABIDI, L. STAUDT, Z. TEZAK, H. HONG a C. WANG. Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing. Nature Biotechnology. 2021, 39(9), 1141-50, ISSN 1087-0156, IF: 54.908, PMID: 34504346
KLEMPT, D., O. BRZON, M. KAŠNÝ, K. KVAPILOVA, P. HUBACEK, A. BRIKSI, M. BEZDICEK, V. KOUDELÁKOVÁ, M. LENGEROVA, M. HAJDÚCH, P. DREVINEK, S. POSPISILOVA, E. KRIEGOVA, E. KRIEGOVA a M. MACEK. Distribution of SARS-CoV-2 Lineages in the Czech Republic, Analysis of Data from the First Year of the Pandemic. Microorganisms. 2021, 9(8), 1671, ISSN 2076-2607, IF: 4.128, PMID: 34442750
PORUBSKÝ, M., K. VYCHODILOVÁ, D. MILICEVIC, M. BUDESINKY, J. STANKOVÁ, P. DŽUBÁK, M. HAJDÚCH a J. HLAVÁČ. Cytotoxicity of Amino-BODIPY Modulated via Conjugation with 2-Phenyl-3-Hydroxy-4(1H)-Quinolinones. ChemistryOpen. 2021, 10(11), 1104-1110, ISSN 2191-1363, IF: 2.911, PMID: 34427046
KVASNIČKA, A., D. FRIEDECKÝ, A. TICHA, R. HYSPLER, H. JANEČKOVÁ, R. BRUMAROVÁ, L. NAJDEKR a Z. ZADAK. SLIDE-Novel Approach to Apocrine Sweat Sampling for Lipid Profiling in Healthy Individuals. International Journal of Molecular Sciences. 2022, 22(15), 8054, ISSN 1422-0067, IF: 5.924, PMID: 34360820
PFISTER, J., M. PETŘÍK, K. BENDOVÁ, B. MATUSZCZAK, U. BINDER, M. MISSLINGER, A. KUHBACHER, F. GSALLER, H. HAAS a C. DECRISTOFORO. Antifungal Siderophore Conjugates for Theranostic Applications in Invasive Pulmonary Aspergillosis Using Low-Molecular TAFC Scaffolds. Journal of Fungi. 2021, 7(7), 558, ISSN 2309-608X , IF: 5.816, PMID: 34356941
IVANOVA (NIKONENKO), A., D. ZANKOV, I. BASKIN, T. MADZHIDOV a P. POLISHCHUK. Multiple Conformer Descriptors for QSAR Modeling. Molecular Informatics. 2021, 40(11), e2060030, ISSN 1868-1743, IF: 3.353, PMID: 34342944
POKORNÝ, J., D. OLEJNÍKOVÁ, I. FRYDRYCH, B. LIŠKOVÁ, S. GURSKÁ, S. BENICKÁ, J. ŠAREK, J. KOTULOVÁ, M. HAJDÚCH, P. DŽUBÁK a M. URBAN. Substituted dienes prepared from betulinic acid - Synthesis, cytotoxicity, mechanism of action, and pharmacological parameters. European Journal of Medicinal Chemistry. 2021, 224, 113706, ISSN 0223-5234, IF: 6.514, PMID: 34311159
KRAJČOVIČOVÁ, S., A. DANIŠKOVÁ, K. BENDOVÁ, Z. NOVÝ, M. SOURAL a M. PETŘÍK. [ 68 Ga]Ga-DFO-c(RGDyK): Synthesis and Evaluation of Its Potential for Tumor Imaging in Mice. International Journal of Molecular Sciences. 2021, 22(14), 7391, ISSN 1422-0067, IF: 5.923, PMID: 34299008
LIGASOVÁ, A. a K. KOBERNA. New Concept and Apparatus for Cytocentrifugation and Cell Processing for Microscopy Analysis. International Journal of Molecular Sciences. 2021, 22(13), 7098, ISSN 1422-0067, IF: 5.923, PMID: 34281153
PURIS, E., ?. KOUŘIL, L. NAJDEKR, S. LOPPI, P. KORHONEN, K. KANNINEN, T. MALM, J. KOISTINAHO, D. FRIEDECKÝ a M. GYNTHER. Metabolomic and lipidomic changes triggered by lipopolysaccharide-induced systemic inflammation in transgenic APdE9 mice. Scientific Reports. 2021, 11(1), 13076, ISSN 2045-2322, IF: 4.379, PMID: 34158563
SOPKO, B., G. TEJRAL, G. BITTI, M. ABATE, M. MEDVEDÍKOVÁ, M. HAJDÚCH, J. CHLOUPEK, J. FAJMONOVA, M. SKORIC, E. AMLER a T. ERBAN. Glyphosate Interaction with eEF1α1 Indicates Altered Protein Synthesis: Evidence for Reduced Spermatogenesis and Cytostatic Effect. ACS Omega. 2021, 6(23), 14848-14857, ISSN 2470-1343, IF: 3.512, PMID: 34151066
RADZIOCH, D., M. GIERA a J.B. DE SANCTIS. Editorial: Quo Vadis Lipid Mediators - Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases. Frontiers in Immunology. 2021, 12, 699276, ISSN 1664-3224, IF: 7.561, PMID: 34054883
MATVEIEVA, M. a P. POLISHCHUK. Benchmarks for interpretation of QSAR models. Journal of Cheminformatics. 2021, 13(1), 41, ISSN 1758-2946, IF: 5.514, PMID: 34039411
TORRES, W., M. CHAVEZ-CASTILLO, J.L. PEREZ VICUNA, R. CARRASQUERO, M.P. DÍAZ, Y. GOMEZ, H. RAMIREZ, C. CANO, J. ROJAS-QUINTERO, M. CHACIN, M. VELASCO, J.B. DE SANCTIS a V. BERMUDEZ. Potential role of bioactive lipids in rheumatoid arthritis. Current Pharmaceutical Design. 2021, 27(44), 4434-4451, ISSN 1381-6128, IF: 3.116, PMID: 34036919
ANNADURAI, N., J.B. DE SANCTIS, M. HAJDÚCH a V. DAS. Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies. Experimental Neurology. 2021, 343, 113756, ISSN 0014-4886, IF: 5.330, PMID: 33989658
PORUBSKÝ, M., S. GURSKÁ, J. STANKOVÁ, M. HAJDÚCH, P. DŽUBÁK a J. HLAVÁČ. AminoBODIPY Conjugates for Targeted Drug Delivery Systems and Real-Time Monitoring of Drug Release. Molecular Pharmaceutics. 2021, 18(6), 2385-2396, ISSN 1543-8384, IF: 3.500, PMID: 33961440
KUGLER, M., J. NEKVINDA, J. HOLUB, S. EL ANWAR, V. DAS, V. SICHA, K.. POSPISILOVA, M. FABRY, V. KRAL, J. BRYNDA, V. KASICKA, M. HAJDÚCH, P. ŘEZÁČOVÁ a B. GRUNER. Inhibitors of CA IX Enzyme Based on Polyhedral Boron Compounds. Chembiochem : a European Journal of Chemical Biology. 2021, 22(18), 2741-2761, ISSN 1439-4227, IF: 3.164, PMID: 33939874
REISSIG, F., D. BAUER, K. ZACHSLER, Z. NOVÝ, K. BENDOVÁ, M. ĹUDIK, K. KOPKA, H.J. PIETZSCH, M. PETŘÍK a C. MAMAT. Towards Targeted Alpha Therapy with Actinium-225: Chelators for Mild Condition Radiolabeling and Targeting PSMA-A Proof of Concept Study. Cancers. 2021, 13(8), 1974, ISSN 2072-6694, IF: 6.126, PMID: 33923965
JAWOREK, H., V. KOUDELÁKOVÁ, I. OBORNA, B. ZBORILOVA, J. BREZINOVA, D. RUZICKOVA, J. VRBKOVÁ, P. KOUŘILOVÁ a M. HAJDÚCH. Prevalence and genotype distribution of human papillomavirus in Czech non-vaccinated heterosexual couples. Virology Journal. 2021, 18(1), 80, ISSN 1743-422X , IF: 2.579, PMID: 33858457
STEFEKOVA, A., P. CAPKOVA, Z. CAPKOVA, V. CURTISOVA, J. SROVNAL, E. MRACKA, E. KLASKOVA a M. PROCHAZKA. MLPA analysis of 32 foetuses with a congenital heart defect and 1 foetus with renal defects - pilot study. The significant frequency rate of presented pathological CNV. Biomedical Papers - Olomouc. 2021, -, -, ISSN 1213-8118, IF: 1.245, PMID: 33824538
NOVÝ, Z., J. JANOUSEK, P. BARTA, M. PETŘÍK, M. HAJDÚCH a F. TREJTNAR. Preclinical evaluation of anti-VEGFR2 monoclonal antibody ramucirumab labelled with zirconium-89 for tumour imaging. Journal of Labelled Compounds & Radiopharmaceuticals. 2021, 64(7), 262-270, ISSN 0362-4803, IF: 1.809, PMID: 33818828
KALITA, O., Z. ŠPORIKOVÁ , M. HAJDÚCH, M. HOUDOVÁ MEGOVÁ , R. SLAVKOVSKÝ, L. HRABALEK, M. HALAJ, Y. KLEMENTOVÁ, M. DOLEZAL, J. DRÁBEK, L. TUCKOVA, J. EHRMANN, J. VRBKOVÁ, R. TROJANEC a M. VAVERKA. The Influence of Gene Aberrations on Survival in Resected IDH Wildtype Glioblastoma Patients: A Single-Institution Study. Current Oncology. 2021, 28(2), 1280-1293, ISSN 1198-0052, IF: 2.257, PMID: 33801093
DE SANCTIS, J.B., A. GARCIA, D. MORENO a M. HAJDÚCH. Coronavirus infection: An immunologists' perspective. Scandinavian Journal of Immunology. 2021, 93(6), e13043, ISSN 0300-9475, IF: 2.717, PMID: 33783027
PERLÍKOVÁ, P., A. KRAJCZYK, E. DOLEZELOVA, M. SLAPNICKOVA, N. MILISAVLJEVIC, L. POSTOVA SLAVETINSKA, E. TLOUŠŤOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, A. ZIKOVA a M. HOCEK. Synthesis and Antitrypanosomal Activity of 6-Substituted 7-Methyl-7-deazapurine Nucleosides. ACS infectious Diseases. 2021, 7(4), 917-926, ISSN 2373-8227, IF: 4.614, PMID: 33769794
ISKAUSKIENE, M., A. KADLECOVA, J. VOLLER, L. JANOVSKA, V. MALINAUSKIENE, A. ZUKAUSKAITE a A. SACKUS. Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress. Archiv der Pharmazie. 2021, 54(6), e2100001, ISSN 0365-6233, IF: 2.590, PMID: 33733468
KOLECKOVA, M., J. EHRMANN, J. BOUCHAL, M. JANÍKOVÁ, A. BRISUDOVA, J. SROVNAL, K. ŠTAFFOVÁ, M. SVOBODA, O. SLABÝ, L. RADOVÁ, K. VOMACKOVA, B. MELICHAR, L. VEVERKOVA a Z. KOLÁŘ. Epithelial to mesenchymal transition and microRNA expression are associated with spindle and apocrine cell morphology in triple-negative breast cancer. Scientific Reports. 2021, 11(1), 5145, ISSN 2045-2322, IF: 3.998, PMID: 33664322
RAMIREZ, H., E. FERNANDEZ, J. RODRIGUES, S. MAYORA, G. MARTINEZ, C. CELIS, J.B. DE SANCTIS, M. MIJARES a J. CHARRIS. Synthesis and antimalarial and anticancer evaluation of 7-chlorquinoline-4-thiazoleacetic derivatives containing aryl hydrazide moieties. Archiv der Pharmazie. 2021, 54(7), e2100002, ISSN 0365-6233, IF: 2.590, PMID: 33660349
KALITA, O., L. HRABALEK, M. HALAJ, P. HOK, D. FRANC, Y. KLEMENTOVÁ, M. DOLEŽEL, E. CECHAKOVA, Z. ŠPORIKOVÁ , J. DRÁBEK, M. HAJDÚCH a L. TUČKOVÁ. Very late complications of oncotherapy in glioblastoma patients: A case series. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia. 2021, 166(2), 236-241, ISSN 1213-8118, IF: 1.000, PMID: 33612837
MAKOVA, B., V. MIK, B. LIŠKOVÁ, G. GONZALES, D. VÍTEK, M. MEDVEDÍKOVÁ, B. MONFORT, V. RUČILOVÁ, A. KADLECOVA, P. KHIRSARIYA, Z. BARREIRO, L. HAVLICEK, M. ZATLOUKAL, M. SOURAL, K. PARUCH, B. D´AUTREAUX, M. HAJDÚCH, M. STRNAD a J. VOLLER. Cytoprotective activities of kinetin purine isosteres. Bioorganic & Medicinal Chemistry. 2021, 1(33), 115993, ISSN 0968-0896, IF: 3.073, PMID: 33497938
CAPKOVA, Z., P. CAPKOVA, J. SROVNAL, K. ADAMOVA, M. PROCHAZKA a M. HAJDÚCH. Duplication of 9p24.3 in three unrelated patients and their phenotypes, considering affected genes, and similar recurrent variants. Molecular Genetics & Genomic Medicine. 2021, 9(3), e1592, ISSN 2324-9269, IF: 1.995, PMID: 33455084
POLISHCHUK, P. CReM: chemically reasonable mutations framework for structure generation. Journal of Cheminformatics. 2020, 12(1), 28, ISSN 1758-2946, IF: 5.326, PMID: 33430959
SVEC, P., Z. NOVÝ, J. KUCKA, M. PETŘÍK, O. SEDLACEK, M. KUCHAR, B. LIŠKOVÁ, M. MEDVEDÍKOVÁ, K. KOLOUCHOVA, O. GROBORZ, L. LOUKOTOVA, R. KONEFAL, M. HAJDÚCH a M. HRUBY. Iodinated Choline Transport-Targeted Tracers. Journal of Medicinal Chemistry. 2020, 63(24), 15960–15978, ISSN 0022-2623, IF: 6.205, PMID: 33271015
DE SANCTIS, J.B., D. DUMUT, D. RADZIOCH a M. HAJDÚCH. Functionally Relevant Differences in Plasma Fatty Acid Composition and Expression of Cytotoxic and Inhibitory NK Cell Receptors between Healthy Young and Healthy Elder Adults. Nutrients. 2020, 12(12), EE3641, ISSN 2072-6643, IF: 4.171, PMID: 33256224
POLISHCHUK, P. Control of Synthetic Feasibility of Compounds Generated with CReM. Journal of chemical information and modeling. 2020, 60(12), 6074-6080, ISSN 1549-9596, IF: 4.549, PMID: 33167612
JURIKOVA, T., D. LUPTAKOVA, O. KOFRONOVA, A. SKRIBA, J. NOVAK, H. MARESOVA, A. PALYZOVA, M. PETŘÍK, V. HAVLÍČEK a O. BENADA. Bringing SEM and MSI Closer Than Ever Before: Visualizing Aspergillus and Pseudomonas Infection in the Rat Lungs. Journal of Fungi. 2020, 6(4), E257, ISSN 2309-608X, IF: 4.621, PMID: 33143040
SCHADICH, E., A.. KRYSHCHYSHYN-DYLEVYCH, S. HOLOTA, P. POLISHCHUK, P. DŽUBÁK, S. GURSKÁ, M. HAJDÚCH a R. LESYK. Assessing different thiazolidine and thiazole based compounds as antileishmanial scaffolds. Bioorganic & Medicinal Chemistry Letters. 2020, 30(23), 127616, ISSN 0960-894X, IF: 2.572, PMID: 33091607
DAS, V. a J.B. DE SANCTIS. Small Natural and Synthetic Molecules for Therapeutic Use. Current Pharmaceutical Design. 2020, 26(35), 4349-4350, ISSN 1381-6128, IF: 2.208, PMID: 33081655
KARASKOVA, E., D. POSPÍŠILOVÁ, M. VELGANOVA-VEGHOVA, M. GERYK, J. VOLEJNÍKOVÁ, D. HOLUB a M. HAJDÚCH. Importance of Hepcidin in the Etiopathogenesis of Anemia in Inflammatory Bowel Disease. Digestive Diseases and Sciences. 2020, 66(10), 3263-3269, ISSN 0163-2116, IF: 2.751, PMID: 33063192
TINKOV, O., P. POLISHCHUK, M. MATVEIEVA, V. GRIGOREV, L. GRIGOREVA a Y. POROZOV. The Influence of Structural Patterns on Acute Aquatic Toxicity of Organic Compounds. Molecular Informatics. 2020, 40(9), e2000209, ISSN 1868-1743, IF: 2.741, PMID: 33029954
NOVÝ, Z., V. LOBAZ, M. VLK, J. KOZEMPEL, P. STEPANEK, M. POPPER, J. VRBKOVÁ, M. HAJDÚCH, M. HRUBY a M. PETŘÍK. Head-To-Head Comparison of Biological Behavior of Biocompatible Polymers Poly(Ethylene Oxide), Poly(2-Ethyl-2-Oxazoline) and Poly[N-(2-Hydroxypropyl)Methacrylamide] as Coating Materials for Hydroxyapatite Nanoparticles in Animal Solid Tumor Model. Nanomaterials. 2020, 10(9), E1690, ISSN 2079-4991, IF: 4.324, PMID: 32867391
SMOLKA, V., M. ROHANOVA, B. LUDÍKOVÁ, Z. NOVÁK, M. ZAPALKA, D. POSPÍŠILOVÁ a J. VOLEJNÍKOVÁ. Severe linezolid-induced lactic acidosis in a child with acute lymphoblastic leukemia: A case report. Journal of Infection and Chemotherapy. 2020, 26(12), 1316-1318, ISSN 1341-321X, IF: 1.722, PMID: 32859497
BALIK, V., P. KOUŘILOVÁ, I. SULLA, J. VRBKOVÁ, J. SROVNAL, I. SULLA a S. TALARI. Comparison of bypass and non-bypass surgical treatments for internal carotid artery blood blister-like aneurysms: a meta-analysis of efficacy, safety and outcomes. World Neurosurgery. 2020, 144, 283-292, ISSN 1878-8750, IF: 1.829, PMID: 32829023
VERMISOGLOU, E., D. PANACEK, K. JAYARAMULU, M. PYKAL, I. FREBORT, M. KOLÁŘ, M. HAJDÚCH, R. ZBOŘIL a M. OTYEPKA. Human virus detection with graphene-based materials. Biosensors & Bioelectronics. 2020, 166, 112436, ISSN 0956-5663, IF: 10.257, PMID: 32750677
PETŘÍK, M., E. UMLAUFOVÁ, V. RACLAVSKÝ, A. PALYZOVA, V. HAVLÍČEK, J. PFISTER, C. MAIR, Z. NOVÝ, M. POPPER, M. HAJDÚCH a C. DECRISTOFORO. 68 Ga-labelled desferrioxamine-B for bacterial infection imaging. European Journal of Nuclear Medicine and Molecular Imaging. 2021, 48(2), 372-382, ISSN 1619-7070, IF: 7.081, PMID: 32734456
FLEUTI, M., K. BARTOVA, L. POSTOVA SLAVETINSKA, E. TLOUŠŤOVÁ, M. TICHÝ, S. GURSKÁ, P. PAVLIŠ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Biological Profiling of Pyrazolo-Fused 7-Deazapurine Nucleosides. The Journal of Organic Chemistry. 2020, 85(16), 10539-10551, ISSN 0022-3263, IF: 4.335, PMID: 32692916
GACHECHILADZE, M., J. ŠKARDA, D. SKANDEROVÁ, I. ÜBERALL, V. KOLEK, P. SMICKOVA, P. VOJTA, J. VRBKOVÁ, M. HAJDÚCH, I. SHANI, Z. KOLÁŘ, R. STAHEL, W. WEDER, U. RULLE, A. SOLTERMANN a M. JOERGER. Prognostic value of tumor-infiltrating lymphocytes (TILs) and their association with PD-L1 expression and DNA repair protein RAD51 in patients with resected non-small cell lung carcinoma. Lung Cancer. 2020, 147, 30-38, ISSN 0169-5002, IF: 4.702, PMID: 32653671
DVOŘANOVÁ ŠTĚPÁNKOVÁ, J., M. KUGLER, J. HOLUB, V. SICHA, V. DAS, J. NEKVINDA, S. EL ANWAR, M. HAVRANEK, K.. POSPISILOVA, M. FABRY, V. KRAL, M. MEDVEDÍKOVÁ, S. MATEJKOVA, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, J. BRYNDA, M. HAJDÚCH, B. GRUNER a P. ŘEZÁČOVÁ. Sulfonamido Carboranes as Highly Selective Inhibitors of Cancer-Specific Carbonic Anhydrase IX. European Journal of Medicinal Chemistry. 2020, 200, 112460, ISSN 0223-5234, IF: 5.572, PMID: 32505851
PETŘÍK, M., J. PFISTER, M. MISSLINGER, C. DECRISTOFORO a H. HAAS. Siderophore-Based Molecular Imaging of Fungal and Bacterial Infections-Current Status and Future Perspectives. Journal of Fungi. 2020, 6(2), E73, ISSN 2309-608X, IF: 4.621, PMID: 32485852
YANG, C., R. POHL, M. TICHÝ, S. GURSKÁ, P. PAVLIŠ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis, Photophysical Properties, and Biological Profiling of Benzothieno-Fused 7-Deazapurine Ribonucleosides. The Journal of Organic Chemistry. 2020, 85(12), 8085-8101, ISSN 0022-3263, IF: 4.335, PMID: 32432875
GARIC, D., D. DUMUT, J. SHAH, J.B. DE SANCTIS a D. RADZIOCH. The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide. Cellular and Molecular Life Sciences. 2020, 77(21), 4255-4267, ISSN 1420-682X, IF: 7.014, PMID: 32394023
CHYRA, Z., T. SEVCIKOVA, P. VOJTA, J. PUTEROVA, L. BROZOVA, K. GROWKOVA, J. FILIPOVA, M. ZATOPKOVA, S. GROSICKI, A. BARCHNICKA, W. JEDRZEJCAK, A. WASCUK-GAJDA, A. JUNGOVA, A. MIKULASOVA, M. HAJDÚCH, M. MOKREJS, L. POUR, M. STORK, L. HARVANOVA, M. MISTRÍK, G. MIKALA, P. ROBAK, A. CZYZ, J. DEBSKI, L. USNARSKA-ZUBKIEWICZ, A. JURCZYSZYN, L. STEJSKAL, G. MORGAN, F. KRYUKOV, E. BUDINSKA, M. SIMICEK, T. JELINEK, M. HRDINKA a R. HAJEK. Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis. Haematologica. 2020, 106(2), 601-604, ISSN 0390-6078, IF: 7.570, PMID: 32381580
SUMMER, D., M. PETŘÍK, S. MAYR, M. HERMANN, P. KAEOPOOKUM, J. PFISTER, M. KLINGER, C. RANGGER, H. HAAS a C. DECRISTOFORO. Hybrid Imaging Agents for Pretargeting Applications Based on Fusarinine C-Proof of Concept. Molecules. 2020, 25(9), pii: E2123, ISSN 1420-3049, IF: 3.060, PMID: 32370017
BALIK, V., P. KOUŘILOVÁ, I. SULLA, J. VRBKOVÁ, J. SROVNAL, M. HAJDÚCH a K. TAKIZAWA. Recurrence of surgically treated parasagittal meningiomas: a meta-analysis of risk factors. Acta Neurochirurgica. 2020, 162(9), 2165-2176, ISSN 0001-6268, IF: 1.834, PMID: 32333274
YOUSSEF, M., J.B. DE SANCTIS, J. SHAH, D. DUMUT, M. HAJDÚCH, B.J. PETROF a D. RADZIOCH. Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis. Lung. 2020, 198(3), 459-469, ISSN 0341-2040, IF: 2.231, PMID: 32306138
VESELOVSKA, L., N. KUDLOVÁ, S. GURSKÁ, B. LIŠKOVÁ, M. MEDVEDÍKOVÁ, O. HODEK, E. TLOUŠŤOVÁ, N. MILISAVLJEVIC, M. TICHÝ, P. PERLÍKOVÁ, H. MERTLIKOVA-KAISEROVA, J. TRYLCOVA, R. POHL, B. KLEPETAROVA, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytotoxic and Antiviral Activity Profiling of All-Four Isomeric Series of Pyrido-Fused 7-Deazapurine Ribonucleosides. Chemistry. 2020, 26(57), 13002-13015, ISSN 0947-6539, IF: 4.857, PMID: 32275109
YOUSSEF, M., J.B. DE SANCTIS, J. SHAH, D. DUMUT, M. HAJDÚCH, A. NAUMOVA a D. RADZIOCH. Treatment of Allergic Asthma With Fenretinide Formulation (LAU-7b) Downregulates ORMDL Sphingolipid Biosynthesis Regulator 3 ( Ormdl3) Expression and Normalizes Ceramide Imbalance. The Journal of Pharmacology and Experimental Therapeutics. 2020, 373(3), 476-487, ISSN 0022-3565, IF: 3.561, PMID: 32273303
SLAVÍK, H., V. BALIK, J. VRBKOVÁ, A. ŘEHULKOVÁ, M. VAVERKA, L. HRABALEK, M. VIDLAŘOVÁ, S. GURSKÁ, M. HAJDÚCH a J. SROVNAL. Identification of Meningioma Patients at High Risk of Tumor Recurrence Using MicroRNA Profiling. Neurosurgery. 2020, 87(5), 1055-1063, ISSN 0148-396X, IF: 4.605, PMID: 32125436
ŘEHULKA, J., K. BÜRGLOVÁ, P. KREJČÍ, S. GURSKÁ, P. HRADIL, M. HAJDÚCH, P. DŽUBÁK a J. HLAVÁČ. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors. European Journal of Medicinal Chemistry. 2020, 192, 112176, ISSN 0223-5234, IF: 4.833, PMID: 32120327
DŽUBÁK, P., S. GURSKÁ, K. BOGDANOVÁ, D. UHRIKOVA, N. KANJAKOVA, S. COMBET, T. KLUNDA, M. KOLÁŘ, M. HAJDÚCH a M. POLÁKOVÁ. Antimicrobial and cytotoxic activity of (thio)alkyl hexopyranosides, nonionic glycolipid mimetics. Carbohydrate Research. 2020, 488, 107905, ISSN 0008-6215, IF: 1.873, PMID: 32004953
PFISTER, J., D. SUMMER, M. PETŘÍK, M. KHOYLOU, A. LICHNIUS, P. KAEOPOOKUM, L. KOCHINKE, T. ORASCH, H. HAAS a C. DECRISTOFORO. Hybrid Imaging of Aspergillus fumigatus Pulmonary Infection with Fluorescent, 68Ga-Labelled Siderophores. Biomolecules. 2020, 10(2), pii: E168, ISSN 2218-273X, IF: 4.694, PMID: 31979017
MADZHIDOV, T., A. RAKHIMBEKOVA, A. KUTLUSHINA a P. POLISHCHUK. Probabilistic Approach for Virtual Screening Based on Multiple Pharmacophores. Molecules. 2020, 25(2), pii: E385, ISSN 1420-3049, IF: 3.060, PMID: 31963467
YOUSSEF, M., J.B. DE SANCTIS, C. KANAGARATHAM, S. TAO, E. AHMED a D. RADZIOCH. Efficacy of Optimized Treatment Protocol Using LAU-7b Formulation against Ovalbumin (OVA) and House Dust Mite (HDM) -Induced Allergic Asthma in Atopic Hyperresponsive A/J Mice. Pharmacological Research. 2020, 37(2), 31, ISSN 0724-8741, IF: 3.896, PMID: 31915990
VOLEJNÍKOVÁ, J., P. VOJTA, H. URBANKOVA, R. MOJZIKOVA, M. HORVÁTHOVÁ, I. HOCHOVA, J. CERMAK, J. BLATNY, M. SUKOVA, E. BUBANSKA, J. FEKETOVA, D. PROCHAZKOVA, J. HORAKOVA, M. HAJDÚCH a D. POSPÍŠILOVÁ. Czech and Slovak Diamond-Blackfan Anemia (DBA) Registry update: Clinical data and novel causative genetic lesions. Blood Cells, Molecules & Diseases. 2020, 81, 102380, ISSN 1079-9796 , IF: 2.305, PMID: 31855845
LUKÁŠ, J., J. DRÁBEK, D. LUKAS, I. ZEMANOVA a A. RULSEH. nenalezen IF?_Ectopic thyroid with benign and malignant findings: A case series. International Journal of Surgery Case Reports. 2019, 66, 33-38, ISSN 2210-2612, IF: ?, PMID: 31790949
LIGASOVÁ, A., M. VYDRZALOVA, R. BURIÁNOVÁ, L. BRUCKOVA, R. VEČEŘOVÁ, A. JANOŠŤÁKOVÁ a K. KOBERNA. A New Sensitive Method for the Detection of Mycoplasmas Using Fluorescence Microscopy. Cells. 2019, 8(12), pii: E1510, ISSN 2073-4409, IF: 5.656, PMID: 31775352
POLISHCHUK, P., A. KUTLUSHINA, D. BASHIROVA, O. MOKSHYNA a T. MADZHIDOV. Virtual Screening Using Pharmacophore Models Retrieved from Molecular Dynamic Simulations. International Journal of Molecular Sciences. 2019, 20(23), pii: E5834, ISSN 1422-0067, IF: 4.183, PMID: 31757043
CAPKOVA, Z., P. CAPKOVA, J. SROVNAL, K. ŠTAFFOVÁ, V. BECVAROVA, M. TRTKOVA, K. ADAMOVA, A. ŠANTAVÁ, V. CURTISOVA, M. HAJDÚCH a M. PROCHAZKA. Differences in the importance of microcephaly, dysmorphism, and epilepsy in the detection of pathogenic CNVs in ID and ASD patients. PeerJ. 2019, 7, e7979, ISSN 2167-8359, IF: 2.353, PMID: 31741789
KAEOPOOKUM, P., M. PETŘÍK, D. SUMMER, M. KLINGER, C. ZHAI, C. RANGGER, R. HAUBNER, H. HAAS, M. HAJDÚCH a C. DECRISTOFORO. Comparison of 68Ga-labeled RGD mono- and multimers based on a clickable siderophore-based scaffold. Nuclear Medicine and Biology. 2019, 78-79, 1-10, ISSN 0969-8051, IF: 2.492, PMID: 31678781
GARIC, D., J.B. DE SANCTIS, D. DUMUT, J. SHAH, J. PENA, M. YOUSSEF, B.J. PETROF, F. KOPŘIVA, J. HANRAHAN, M. HAJDÚCH a D. RADZIOCH. Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction. Biochimica et biophysica acta. Molecular and cell biology of lipids. 2019, 1865(2), 158538, ISSN 1388-1981, IF: 4.402, PMID: 31678518
BORKOVÁ, L., I. FRYDRYCH, N. JAKUBCOVÁ, R. ADÁMEK, B. LIŠKOVÁ, S. GURSKÁ, M. MEDVEDÍKOVÁ, M. HAJDÚCH a M. URBAN. Synthesis and biological evaluation of triterpenoid thiazoles derived from betulonic acid, dihydrobetulonic acid, and ursonic acid. European Journal of Medicinal Chemistry. 2019, 185, 111806, ISSN 0223-5234, IF: 4.833, PMID: 31677446
GRUNER, B., J. BRYNDA, V. DAS, V. SICHA, J. ŠTĚPÁNKOVÁ, J. NEKVINDA, J. HOLUB, K.. POSPISILOVA, M. FABRY, P. PACHL, V. KRAL, M. KUGLER, V. MAŠEK, M. MEDVEDÍKOVÁ, S. MATEJKOVA, A. NOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH a P. ŘEZÁČOVÁ. Metallacarborane Sulfamides: Unconventional, Specific, and Highly Selective Inhibitors of Carbonic Anhydrase IX. Journal of Medicinal Chemistry. 2019, 62(21), 9560-9575, ISSN 0022-2623, IF: 6.054, PMID: 31568723
PERLÍKOVÁ, P., M. KVASNICA, M. URBAN, M. HAJDÚCH a J. ŠAREK. 2-Deoxyglycoside Conjugates of Lupane Triterpenoids with High Cytotoxic Activity-Synthesis, Activity, and Pharmacokinetic Profile. Bioconjugate Chemistry. 2019, 30(11), 2844-2858, ISSN 1043-1802, IF: 4.349, PMID: 31553559
KADLECOVA, A., B. MAKOVA, M. ARTAL-SANZ, M. STRNAD a J. VOLLER. The plant hormone kinetin in disease therapy and healthy aging. Ageing Rsearch Reviews. 2019, 55, 100958, ISSN 1568-1637, IF: 10.390, PMID: 31479763
MARTINEZ, G., M. MIJARES, K. CHAVEZ, A. SUAREZ, R. COMPAGNONE, P. CHIRINOS a J.B. DE SANCTIS. Caracasine acid, an ent-3,4-seco-kaurene, promotes apoptosis and cell differentiation through NFkB signal pathway inhibition in leukemia cells. European Journal of Pharmacology. 2019, 862, 172624, ISSN 0014-2999, IF: 3.170, PMID: 31449809
KARASKOVA, E., J. VOLEJNÍKOVÁ, D. HOLUB, M. VELGANOVA-VEGHOVA, M. SPENEROVA, V. MIHÁL a D. POSPÍŠILOVÁ. Changes in serum hepcidin levels in children with inflammatory bowel disease during anti-inflammatory treatment. Journal of Paediatrics and Child Health. 2019, 56(2), 276-282, ISSN 1034-4810, IF: 1.688, PMID: 31411363
NOWIKOW, C., R. FUERST, M. KAUDERER, C. DANK, W. SCHMID, M. HAJDÚCH, J. ŘEHULKA, S. GURSKÁ, O. MOKSHYNA, P. POLISHCHUK, I. ZUPKO, P. DŽUBÁK a U. RINNER. Synthesis and biological evaluation of cis-restrained carbocyclic combretastatin A-4 analogs: Influence of the ring size and saturation on cytotoxic properties. Bioorganic & Medicinal Chemistry. 2019, 27(19), 115032, ISSN 0968-0896, IF: 2.802, PMID: 31401010
ŠKROTT, Z., D. MAJERA, J. GURSKÝ, T. BUCHTOVÁ, M. HAJDÚCH, M. MISTRÍK a J. BÁRTEK. Disulfiram's anti-cancer activity reflects targeting NPL4, not inhibition of aldehyde dehydrogenase. Oncogene. 2019, 38(40), 6711-6722, ISSN 0950-9232, IF: 6.634, PMID: 31391554
JAWOREK, H., K. KUBÁŇOVÁ, V. KOUDELÁKOVÁ, R. SLAVKOVSKÝ, J. DRÁBEK a M. HAJDÚCH. Pitfalls of commercially available HPV tests in HPV68a detection. PLOS One. 2019, 14(8), e0220373, ISSN 1932-6203, IF: 2.776, PMID: 31381580
FRIEDECKÁ, J., M. JORENEK, K. POSPISKOVA, L. NAJDEKR, L. ZAJONCOVA, D. FRIEDECKÝ a T. ADAM. Urease-immobilized magnetic microparticles in urine sample preparation for metabolomic analysis by gas chromatography-mass spectrometry. Journal of Chromatography. A. 2019, 1605, 360355, ISSN 0021-967, IF: 3.858, PMID: 31315811
NOVÝ, Z., J. ŠTĚPÁNKOVÁ, M.. HOLÁ, D. FLAŠAROVÁ, M. POPPER a M. PETŘÍK. Preclinical Evaluation of Radiolabeled Peptides for PET Imaging of Glioblastoma Multiforme. Molecules. 2019, 24(13), pii: E2496, ISSN 1420-3049, IF: 3.060, PMID: 31288488
VOLLER, J., L. ZAHAJSKA, L. PLÍHALOVÁ, J. JERABKOVA, D. BURGET, A. PATAKI, V. KRYŠTOF, M. ZATLOUKAL, J. BRABEK, D. ROSEL, V. MIK, M. TKAC, T. POSPÍŠIL, T. GUCKÝ, K. DOLEZAL a M. STRNAD. 6-Substituted purines as ROCK inhibitors with anti-metastatic activity. Bioorganic Chemistry. 2019, 90, 103005, ISSN 0045-2068, IF: 3.926, PMID: 31271944
LIGASOVÁ, A. a K. KOBERNA. Quantification of fixed adherent cells using a strong enhancer of the fluorescence of DNA dyes. Scientific Reports. 2019, 9(1), 8701, ISSN 2045-2322 , IF: 4.122, PMID: 31213648
SOCAN, A., M. PETŘÍK, P. PEITL KOLENC, M. KROSELJ, C. RANGGER, Z. NOVÝ, U. SVAJGER, T. GMEINER a C. DECRISTOFORO. On-cartridge preparation and evaluation of 68Ga-, 89Zr- and 64Cu-precursors for cell radiolabelling. Nuclear Medicine and Biology. 2019, 71, 23-31, ISSN 0969-8051, IF: 2.203, PMID: 31128475
LOBAZ, V., R. KONEFAL, J. PANEK, M. VLK, J. KOZEMPEL, M. PETŘÍK, Z. NOVÝ, S. GURSKÁ, P. ZNOJEK, P. STEPANEK a M. HRUBY. In Situ In Vivo radiolabeling of polymer-coated hydroxyapatite nanoparticles to track their biodistribution in mice. Colloids and surfaces. B, Biointerfaces. 2019, 179, 143-152, ISSN 0927-7765, IF: 3.997, PMID: 30954015
TINKOV, O., V. GRIGOREV, P. POLISHCHUK, A. YARKOV a O. RAEVSKY. nemá IF a dedi_nezadávat_[QSAR investigation of acute toxicity of organic compounds during oral administration to mice]. Biomedit︠s︡inskai︠a︡ Khimii︠a︡. 2019, 65(2), 123-132, ISSN 2310-6972, IF: ?, PMID: 30950817
GARIC, D., J.B. DE SANCTIS, J. SHAH, D. DUMUT a D. RADZIOCH. Biochemistry of very-long-chain and long-chain ceramides in cystic fibrosis and other diseases: The importance of side chain. Progress in Lipid Research. 2019, 74, 130-144, ISSN 0163-7827, IF: 8.435, PMID: 30876862
KAEOPOOKUM, P., D. SUMMER, J. PFISTER, T. ORASCH, B. LECHNER, M. PETŘÍK, Z. NOVÝ, B. MATUSZCZAK, C. RANGGER, H. HAAS a C. DECRISTOFORO. Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection. Molecular Imaging and Biology. 2019, 21(6), 1097-1106, ISSN 1536-1632, IF: 3.626, PMID: 30838551
HOLUB, D., P. FLODROVÁ, T. PIKA, P. FLODR, M. HAJDÚCH a P. DŽUBÁK. Mass Spectrometry Amyloid Typing Is Reproducible across Multiple Organ Sites. Biomed Research International. 2019, 2019, 3689091, ISSN 2314-6133, IF: 2.583, PMID: 30834260
JANOUSEK, J., P. BARTA, Z. NOVÝ, K. ZILKOVA a F. TREJTNAR. Antiangiogenic Human Monoclonal Antibody Ramucirumab Radiolabelling: In Vitro Evaluation on VEGFR2-positive Cell Lines. Anticancer Research. 2019, 39(2), 735-744, ISSN 0250-7005, IF: 1.865, PMID: 30711952
CAPKOVA, P., J. SROVNAL, Z. CAPKOVA, K. ŠTAFFOVÁ, V. BECVAROVA, M. TRKOVA, K. ADAMOVA, A. ŠANTAVÁ, V. CURTISOVA, M. HAJDÚCH a M. PROCHAZKA. MLPA is a practical and complementary alternative to CMA for diagnostic testing in patients with autism spectrum disorders and identifying new candidate CNVs associated with autism. PeerJ. 2019, 6, e6183, ISSN 2167-8359, IF: 2.118, PMID: 30647996
JAWOREK, H., V. KOUDELÁKOVÁ, R. SLAVKOVSKÝ, J. DRÁBEK a M. HAJDÚCH. The absence of high-risk human papillomavirus in Czech non-small cell lung cancer cases. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2020, 164(1), 71-76, ISSN 1213-8118, IF: 1.087, PMID: 30631209
KUTLUSHINA, A., A. KHAKIMOVA, T. MADZHIDOV a P. POLISHCHUK. Ligand-Based Pharmacophore Modeling Using Novel 3D Pharmacophore Signatures. Molecules. 2019, 23(12), pii: E3094, ISSN 1420-3049, IF: 3.098, PMID: 30486389
GIMADIEV, T., T. MADZHIDOV, I. TETKO, R. NUGMANOV, I. CASCIUS, O. KLIMCHUK, A. BODROV, P. POLISHCHUK, I. ANTIPIN a A. VARNEK. Bimolecular Nucleophilic Substitution Reactions: Predictive Models for Rate Constants and Molecular Reaction Pairs Analysis. Molecular Informatics. 2018, 38(4), e1800104, ISSN 1868-1743, IF: 1.955, PMID: 30468317
TEMIGRAZIYEV, B., K. KUCAKOVA, Y. BAIZHIGIT, M. JURÁŠEK, P. DŽUBÁK, M. HAJDÚCH, B.. DOLENSKY, P. DRAŠAR, B. TULEUOV a S. ADEKENOV. Bioavailability and structural study of 20-hydroxyecdysone complexes with cyclodextrins. Steroids. 2019, 18147, 37-41, ISSN 0039-128X, IF: 2.523, PMID: 30458190
LIGASOVÁ, A. a K. KOBERNA. DNA Replication: From Radioisotopes to Click Chemistry. Molecules. 2018, 23(11), pii: E3007, ISSN 1420-3049, IF: 3.098, PMID: 30453631
PETŘÍK, M., E. UMLAUFOVÁ, V. RACLAVSKÝ, A. PALYZOVA, V. HAVLICEK, H. HAAS, Z. NOVÝ, D. DOLEŽAL, M. HAJDÚCH a C. DECRISTOFORO. Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography. Scientific Reports. 2018, 8(1), 15698, ISSN 2045-2322 , IF: 4.122, PMID: 30356077
SKRIBA, A., T. PLUHACEK, A. PALYZOVA, Z. NOVÝ, K. LEMR, M. HAJDÚCH, M. PETŘÍK a V. HAVLICEK. Early and Non-invasive Diagnosis of Aspergillosis Revealed by Infection Kinetics Monitored in a Rat Model. Frontiers in Microbiology. 2018, 9, 2356, ISSN 1664-302X, IF: 4.019, PMID: 30349512
MATVEIEVA, M., M. CRONIN a P. POLISHCHUK. Interpretation of QSAR Models: Mining Structural Patterns Taking into Account Molecular Context. Molecular Informatics. 2018, 38(3), e1800084, ISSN 1868-1743, IF: 1.955, PMID: 30346106
TOKARENKO, A., B. LIŠKOVÁ, S. SMOLEN, N. TÁBORSKÁ, M. TICHÝ, S. GURSKÁ, P. PERLÍKOVÁ, I. FRYDRYCH, E. TLOUŠŤOVÁ, P. ZNOJEK, H. MERTLIKOVA-KAISEROVA, L. POSTOVA SLAVETINSKA, R. POHL, B. KLEPETAROVA, N. KHALID, Y. WENREN, R. LAPOSA, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2018, 61(20), 9347-9359, ISSN 0022-2623, IF: 6.253, PMID: 30281308
BRIZA, T., J. KRALOVA, S. RIMPELOVA, M. HAVLIK, R. KAPLANEK, Z. KEJIK, P. MARTASEK, I. MIKULA, P. DŽUBÁK, M. HAJDÚCH, T. RUML a V. KRAL. Pentamethinium salts as ligands for cancer: Sulfated polysaccharide co-receptors as possible therapeutic target. Bioorganic Chemistry. 2019, 73, 74-85, ISSN 0045-2068, IF: 3.929, PMID: 30273836
JAWOREK, H., V. KOUDELÁKOVÁ, J. DRÁBEK, J. VRBKOVÁ, B. ZBORILOVA, I. OBORNA, J. BREZINOVA, R. MAREK, K. HUML, P. VANEK a M. HAJDÚCH. A Head-to-Head Analytical Comparison of Cobas 4800 HPV, PapilloCheck HPV: Screening, and LMNX Genotyping Kit HPV GP for Detection of Human Papillomavirus DNA in Cervical and Cervicovaginal Swabs. The Journal of Molecular Diagnostics. 2018, 20(6), 849-858, ISSN 1525-1578, IF: 4.880, PMID: 30165205
AGRAWAL, K., V. DAS, N. TÁBORSKÁ, J. GURSKÝ, P. DŽUBÁK a M. HAJDÚCH. Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs. Stem Cells International. 2018, 2018, 6013728, ISSN 1687-966X, IF: 3.989, PMID: 30158986
ŠPORIKOVÁ , Z., V. KOUDELÁKOVÁ, R. TROJANEC a M. HAJDÚCH. Genetic Markers in Triple-Negative Breast Cancer. Clinical Breast Cancer. 2018, 18(5), e841-e850, ISSN 1526-8209, IF: 2.703, PMID: 30146351
KONC, J., M. TICHÝ, R. POHL, J. HODEK, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Sugar modified pyrimido[4,5-b]indole nucleosides: synthesis and antiviral activity. MedChemComm. 2018, 8(9), 1856-1862, ISSN 2040-2503, IF: 2.342, PMID: 30108897
PEXA, T., J. KRAJSA, M. SANKOVA, P. VELEMINSKY, J. HAVRDA, T. KOTRLY a J. DRÁBEK. Identification of the skeletal remains of the Czech communist regime crime victim, priest Josef Toufar. Forensic Science International. 2018, 291, e13-e17, ISSN 0379-0738, IF: 1.974, PMID: 30037506
KARASKOVA, E., J. VOLEJNÍKOVÁ, D. HOLUB, M. VELGANOVA-VEGHOVA, L. SULOVSKÁ, V. MIHÁL, M. HORVÁTHOVÁ a D. POSPÍŠILOVÁ. Hepcidin in newly diagnosed inflammatory bowel disease in children. Journal of Paediatrics and Child Health. 2018, 54(12), 1362-1367, ISSN 1034-4810, IF: 3.595, PMID: 29923651
MEDKOVA, A., J. SROVNAL, J. POTOMKOVA, J. VOLEJNÍKOVÁ a V. MIHÁL. Multifarious diagnostic possibilities of the S100 protein family: predominantly in pediatrics and neonatology. World Journal of Pediatrics. 2018, 14(4), 315-321, ISSN 1708-8569, IF: 1.164, PMID: 29858979
JURÁŠEK, M., M. CERNOHORSKA, J. ŘEHULKA, V. SPIWOK, T. SULIMENKO, E. DRABEROVA, M. DARMOSTUK, S. GURSKÁ, I. FRYDRYCH, R. BURIÁNOVÁ, T. RUML, M. HAJDÚCH, P. BARTŮNĚK, P. DRABER, P. DŽUBÁK, P. DRAŠAR a D. SEDLÁK. Estradiol Dimer Inhibits Tubulin Polymerization and Microtubule Dynamics. The Journal of Steroid Biochemistry and Molecular Biology. 2018, 183, 68-79, ISSN 0960-0760, IF: 4.561, PMID: 29803726
MRAZKOVA, B., R. DZIJAK, T. IMRICHOVA, L. KYJACOVA, P. BARATH, P. DŽUBÁK, D. HOLUB, M. HAJDÚCH, Z. NAHACKA, L. ANDERA, P. HOLICEK, P. VASICOVA, O. SAPEGA, J. BÁRTEK a Z. HODNY. Induction, regulation and roles of neural adhesion molecule L1CAM in cellular senescence. Aging. 2018, 10(3), 432-462, ISSN 1945-4589, IF: 4.867, PMID: 29615539
URBANOVSKÁ, I., M. HOUDOVÁ MEGOVÁ , Z. DWIGHT, O. KALITA, M. UVÍROVÁ, J. SIMOVA, L. TUČKOVÁ, P. BUZRLA, T. PALECEK, M. HAJDÚCH, J. DVORACKOVA a J. DRÁBEK. IDH Mutation Analysis in Glioma Patients by CADMA Compared with SNaPshot Assay and two Immunohistochemical Methods. Pathology & Oncology Research. 2018, 2018, 1-8, ISSN 1219-4956, IF: 1.935, PMID: 29556922
TULPOVA, Z., M. LUO, H. TOEGELOVA, P. VISENDI, S. HAYASHI, P. VOJTA, E. PAUX, A. KILIAN, M. ABROUK, J. BARTOS, M. HAJDÚCH, J. BATLEY, D. EDWARDS, J. DOLEZEL a H. SIMKOVA. Integrated physical map of bread wheat chromosome arm 7DS to facilitate gene cloning and comparative studies. New Biotechmology. 2019, 48, 12-19, ISSN 1871-6784, IF: 3.813, PMID: 29526810
BÜRGLOVÁ, K., G. RYLOVÁ, A. MARKOS, H. PŘICHYSTALOVÁ, M. SOURAL, M. PETRÁČEK, M. MEDVEDÍKOVÁ, G. TEJRAL, B. SOPKO, P. HRADIL, P. DŽUBÁK, M. HAJDÚCH a J. HLAVÁČ. Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1 H)-quinolinones as Novel Ligands with Anticancer Activity. Journal of Medicinal Chemistry. 2018, 61(7), 3027-3036, ISSN 0022-2623, IF: 6.259, PMID: 29498519
VOLEJNÍKOVÁ, J., J. ZAPLETALOVÁ, M. JAROSOVA, H. URBANKOVA, E. KLASKOVA, M. HOROWITZ, M. HAJDÚCH a V. MIHÁL. Acute lymphoblastic leukemia in a child with Leri-Weill syndrome and complete SHOX gene deletion: A Case Report. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2018, 162(1), 65-70, ISSN 1213-8118, IF: 0.894, PMID: 29469136
CHYRA KUFOVA, Z., T. SEVCIKOVA, J. JANUSKA, P. VOJTA, A. BODAY, P. VANICKOVA, J. FILIPOVA, K. GROWKOVA, T. JELINEK, M. HAJDÚCH a R. HAJEK. Newly designed 11-gene panel reveals first case of hereditary amyloidosis captured by massive parallel sequencing. Journal of Clinical Pathology. 2018, 71(8), 687-694, ISSN 0021-9746, IF: 2.687, PMID: 29455155
AGRAWAL, K., V. DAS, P. VYAS a M. HAJDÚCH. Nucleosidic DNA demethylating epigenetic drugs - A comprehensive review from discovery to clinic. Pharmacology & Therapeutics. 2018, 188, 45-79, ISSN 0163-7258, IF: 11.127, PMID: 29454856
FLODROVÁ, P., P. FLODR, T. PIKA, J. VYMETAL, D. HOLUB, P. DŽUBÁK, M. HAJDÚCH a V. SCUDLA. Cardiac amyloidosis: from clinical suspicion to morphological diagnosis. Pathology. 2018, 50(3), 261-268, ISSN 0031-3025, IF: 2.709, PMID: 29448998
POKORNÝ, J., S. KRAJČOVIČOVÁ, M. HAJDÚCH, M. HOLOUBEK, S. GURSKÁ, P. DŽUBÁK, T. VOLNÁ, I. POPA a M. URBAN. Triterpenic azines, a new class of compounds with selective cytotoxicity to leukemia cells CCRF-CEM. Future Medicinal Chemistry. 2018, 10(5), 483-491, ISSN 1756-8919, IF: 3.566, PMID: 29424548
KRAJČOVIČOVÁ, S., J. STANKOVÁ, P. DŽUBÁK, M. HAJDÚCH, M. SOURAL a M. URBAN. A Synthetic Approach for the Rapid Preparation of BODIPY Conjugates and their use in Imaging of Cellular Drug Uptake and Distribution. Chemistry- A European Journal. 2018, 24(19), 4957-4966, ISSN 0947-6539, IF: 5.317, PMID: 29411907
KLEIN, P., M. SOJKA, J. KUČERA, J. MATONOHOVA, V. PAVLIK, J. NEMEC, G. KUBICKOVA, R. SLAVKOVSKÝ, K. SZUSZKIEWICZ, P. DANEK, M. ROZKOT a V. VELEBNY. A porcine model of skin wound infected with a polybacterial biofilm. Biofouling. 2018, 34(2), 226-236, ISSN 0892-7014, IF: 3.080, PMID: 29405092
ŘEHULKA, J., N. ANNADURAI, I. FRYDRYCH, P. DŽUBÁK, M. MILLER, M. HAJDÚCH a V. DAS. Peloruside A-Induced Cell Death in Hypoxia Is p53 Dependent in HCT116 Colorectal Cancer Cells. Journal of Natural Products. 2018, 81(3), 634-640, ISSN 0163-3864, IF: 3.281, PMID: 29400463
SESTAK, S., M. BELLA, T. KLUNDA, S. GURSKÁ, P. DŽUBÁK, F. WÖLS, I. WILSON, V. SLADEK, M. HAJDÚCH, M. POLÁKOVÁ a J. KONA. N-Benzyl Substitution of Polyhydroxypyrrolidines: The Way to Selective Inhibitors of Golgi α-Mannosidase II. ChemMedChem. 2018, 13(4), 373-383, ISSN 1860-7179, IF: 3.225, PMID: 29323461
CAPKOVA, P., A. ŠANTAVÁ, I. MARKOVA, A. STEFEKOVA, J. SROVNAL, K. ŠTAFFOVÁ a V. DURDOVA. Haploinsufficiency of BMP4 and OTX2 in the Foetus with an abnormal facial profile detected in the first trimester of pregnancy. Molecular Cytogenetics. 2017, 10, 47, ISSN 1755-8166, IF: 1.455, PMID: 29299063
KADLECOVA, A., T. JIRSA, O. NOVAK, J. KAMMENGA, M. STRNAD a J. VOLLER. Natural plant hormones cytokinins increase stress resistance and longevity of Caenorhabditis elegans. Biogerontology. 2017, 19(2), 109-120, ISSN 1389-5729, IF: 3.231, PMID: 29255944
ŠKROTT, Z., M. MISTRÍK, K. ANDERSEN, S. FRIIS, D. MAJERA, J. GURSKÝ, T. OŽDIAN, J. BARTKOVA, Z. TURI, P. MOUDRÝ, M. KRAUS, M. MEDVEDÍKOVÁ, J. VÁCLAVKOVÁ, P. DŽUBÁK, I. VROBEL, P. POUCKOVA, J. SEDLACEK, A. MIKLOVICOVA, A. KUTT, J. MATTOVA, C. DRIESSEN, Q. DOU, J. OLSEN, M. HAJDÚCH, B. CVEK, R. DESHAIES a J. BÁRTEK. Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4. Nature. 2017, 552(7684), 194-199, ISSN 0028-0836, IF: 40.137, PMID: 29211715
LUPTAKOVA, D., T. PLUHACEK, M. PETŘÍK, J. NOVAK, A. PALYZOVA, L. SOKOLOVA, A. SKRIBA, B. SEDIVA, K. LEMR a V. HAVLICEK. Non-invasive and invasive diagnoses of aspergillosis in a rat model by mass spectrometry. Scientific Reports. 2017, 7(1), 16523, ISSN 2045-2322, IF: 4.529, PMID: 29184111
VÁCLAVÍK, J., K. COENE, I. VROBEL, L. NAJDEKR, D. FRIEDECKÝ, R. KARLÍKOVÁ, L. MÁDROVÁ, A. PETSALO, U. ENGELKE, A. VAN WEGBERG, L. KLUIJTMANS, T. ADAM a R. WEVERS. Structural elucidation of novel biomarkers of known metabolic disorders based on multistage fragmentation mass spectra. Journal of Inherited Metabolic Disease. 2018, 41(3), 407-414, ISSN 0141-8955, IF: 3.970, PMID: 29139026
VOLEJNÍKOVÁ, J., J. HORACEK a F. KOPŘIVA. Dapsone treatment is efficient against persistent cutaneous and gastrointestinal symptoms in children with Henoch-Schönlein purpura. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2018, 162(2), 154-158, ISSN 1213-8118, IF: 1.087, PMID: 29097818
MODER, M., G. VELIMEZI, M. OWUSU, A. MAZOUZI, M. WIEDNER, J. FERREIRA DA SILVA, L. ROBINSON-GARCIA, F. SCHISCHLIK, R. SLAVKOVSKÝ, R. KRALOVICS, B. SCHUSTER, C. BOCK, T. IDEKER, S. JACKSON, J. MENCHE a J. LOIZOU. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nature Communications. 2017, 8(1), 1238, ISSN 2041-1723, IF: 12.124, PMID: 29089570
EIGNEROVA, B., M. TICHÝ, J. KRASULOVA, L. RAROVA, R. CHRISTOVÁ, M. URBAN, B. BEDNARCZYK-CWYNAR, M. HAJDÚCH a J. ŠAREK. Q1_Synthesis and antiproliferative properties of new hydrophilic esters of triterpenic acids. European Journal of Medicinal Chemistry. 2017, 140, 403-420, ISSN 0223-5234, IF: 4.519, PMID: 28987603
PLEVOVA, P., M. PAPRSKÁŘOVÁ, P. TVRDA, P. TURSKA, R. SLAVKOVSKÝ a E. MRAZKOVA. STRC Deletion is a Frequent Cause of Slight to Moderate Congenital Hearing Impairment in the Czech Republic. Otology & Neurotology. 2017, 38(10), e393-e400, ISSN 1531-7129, IF: 2.024, PMID: 28984810
POLISHCHUK, P. Interpretation of Quantitative Structure-Activity Relationship Models: Past, Present, and Future. Journal of Chemical Information and Modeling. 2017, 57(11), 2618-2639, ISSN 1549-9596, IF: 3.760, PMID: 28949520
KARLÍKOVÁ, R., K. MIČOVÁ, L. NAJDEKR, A. GARDLO, T. ADAM, P. MAJEROVÁ, D. FRIEDECKÝ a A. KOVAC. Metabolic status of CSF distinguishes rats with tauopathy from controls. Alzheimer's Research & Therapy. 2017, 9(1), 78, ISSN 1758-9193, IF: 6.154, PMID: 28934963
USSI, A.E., M. DE KORT, N.P. COUSSENS, T. AITTOKALLIO a M. HAJDÚCH. In Search of System-Wide Productivity Gains - The Role of Global Collaborations in Preclinical Translation. Clinical and Translational Science. 2017, 10(6), 423-425, ISSN 1752-8054, IF: 0.860, PMID: 28929592
VRABLIKOVA, A., L. CZERNEKOVA, R. CAHLIKOVA, Z. NOVÝ, M. PETŘÍK, S. IMRAN, Z. NOVÁK, M. KŘUPKA, V. CEROVSKY, J. TURANEK a M. RAŠKA. Lasioglossins LLIII affects the morphogenesis of Candida albicans and reduces the duration of experimental vaginal candidiasis in mice. Microbiology and Immunology. 2017, 61(11), 474-481, ISSN 0385-5600, IF: 1.706, PMID: 28892177
CAMATEROS, P., C. KANAGARATHAM, L. NAJDEKR, D. HOLUB, J. VRBKOVÁ, L. COTE, J. FOURNIER, J. GOURDON, D. CREERY, R. OLIVENSTEIN, F. KOPŘIVA, T. ADAM, D. FRIEDECKÝ, P. DŽUBÁK, M. HAJDÚCH a D. RADZIOCH. Toll-Like Receptor 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates. American Journal of Respiratory Cell and Molecular Biology. 2018, 58(1), 55-65, ISSN 1044-1549, IF: 4.100, PMID: 28850259
POLISHCHUK, P., T. MADZHIDOV, T. GIMADIEV, A. BODROV, R. NUGMANOV a A. VARNEK. Structure-reactivity modeling using mixture-based representation of chemical reactions. Journal of Computer-aided Molecular Design. 2017, 31(9), 829-839, ISSN 0920-654X, IF: 3.028, PMID: 28752345
GARIC, D., J.B. DE SANCTIS, G. WOJEWODKA, D. HOULE, S. CUPRI, A. ABU-ARISH, J. HANRAHAN, M. HAJDÚCH, E. MATOUK a D. RADZIOCH. Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside. Journal of Molecular Medicine. 2017, 95(10), 1053-1064, ISSN 0946-2716, IF: 4.686, PMID: 28695226
KLIMENKO, K., S. LYAHKOV, M. SHIBINSKAYA, A. KARPENKO, G. MARCOU, D. HORVATH, M. ZENKOVA, E. GONCHAROVA, R. AMIRKHANOV, A. KRYSKO, S. ANDRONATI, I. LEVANDOVSKIY, P. POLISHCHUK, V. KUZMIN a A. VARNEK. Virtual screening, synthesis and biological evaluation of DNA intercalating antiviral agents. Bioorganic & Medicinal Chemistry Letters. 2017, 27(16), 3915-3919, ISSN 0960-894X, IF: 2.454, PMID: 28666733
ANNADURAI, N., K. AGRAWAL, P. DŽUBÁK, M. HAJDÚCH a V. DAS. Microtubule affinity-regulating kinases are potential druggable targets for Alzheimer's disease. Cellular and Molecular Life Sciences. 2017, 74(22), 4159-4169, ISSN 1420-682X, IF: 5.788, PMID: 28634681
NARDONE, G., J. OLIVER-DE LA CRUZ, J. VRBSKY, C. MARTINI, J. PRIBYL, P. SKLADAL, M. PESL, G. CALUORI, S. PAGLIARI, F. MARTINO, Z. MACEČKOVÁ, M. HAJDÚCH, A. SANZ-GARCIA, N. PUGNO, G. STOKIN a G. FORTE. YAP regulates cell mechanics by controlling focal adhesion assembly. Nature Communications. 2017, 15, 8:15321, ISSN 2041-1723, IF: 11.329, PMID: 28504269
OŽDIAN, T., D. HOLUB, Z. MACEČKOVÁ, L. VARANASI, G. RYLOVÁ, J. ŘEHULKA, J. VÁCLAVKOVÁ, H. SLAVÍK, P. MOUDRÝ, P. ZNOJEK, J. STANKOVÁ, J.B. DE SANCTIS, M. HAJDÚCH a P. DŽUBÁK. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells. Journal of Proteomics. 2017, 162, 73-85, ISSN 1874-3919 , IF: 3.867, PMID: 28478306
SUMMER, D., L. GROSSRUBATSCHER, M. PETŘÍK, T. MICHALČÍKOVÁ, Z. NOVÝ, C. RANGGER, M. KLINGER, E. VON GUGGENBERG, R. HAUBNER, P. KAEOPOOKUM, H. HAAS a C. DECRISTOFORO. Developing targeted hybrid imaging probes by chelator scaffolding. Bioconjugate Chemistry. 2017, 28(6), 1722-1733, ISSN 1043-1802, IF: 4.500, PMID: 28462989
VAN GOOL, A., F. BIETRIX, E. CALDENHOVEN, K. ZATLOUKAL, A. SCHERER, J. LITTON, G. MEIJER, N. BLOMBERG, A. SMITH, B. MONS, J. HERINGA, W. KOOT, M. SMIT, M. HAJDÚCH, T. RIJNDERS a A.E. USSI. Bridging the translational innovation gap through good biomarker practice. Nature Reviews. Drug Discovery. 2017, 16(9), 587-588, ISSN 1474-1776 , IF: 57.000, PMID: 28450744
VROBEL, I., D. FRIEDECKÝ, E. FABER, L. NAJDEKR, K. MIČOVÁ, R. KARLÍKOVÁ a T. ADAM. Novel sulphur-containing imatinib metabolites found by untargeted LC-HRMS analysis. European Journal of Pharmaceutical Sciences. 2017, -, -, ISSN 0928-0987, IF: 3.773, PMID: 28433749
LIGASOVÁ, A., P. KONEČNÝ, I. FRYDRYCH a K. KOBERNA. Cell cycle profiling by image and flow cytometry: The optimised protocol for the detection of replicational activity using 5-Bromo-2'-deoxyuridine, low concentration of hydrochloric acid and exonuclease III. PLOS One. 2017, 12(4), e0175880, ISSN 1932-6203, IF: 3.057, PMID: 28426799
ŘEHULKA, J., N. ANNADURAI, I. FRYDRYCH, P. ZNOJEK, P. DŽUBÁK, P. NORTHCOTE, J.H. MILLER, M. HAJDÚCH a V. DAS. Cellular effects of the microtubule-targeting agent peloruside A in hypoxia-conditioned colorectal carcinoma cells. Biochimica et Biophysica Acta. 2017, 17, 30124-1, ISSN 0304-4165, IF: 5.083, PMID: 28366502
DAS, V., T. FÜRST, S. GURSKÁ, P. DŽUBÁK a M. HAJDÚCH. Evaporation-reducing Culture Condition Increases the Reproducibility of Multicellular Spheroid Formation in Microtiter Plates. Journal of Visualized Experiments. 2017, 121, doi: 10.3791/55403, ISSN 1940-087X, IF: 1.113, PMID: 28362402
LIGASOVÁ, A., P. KONEČNÝ, I. FRYDRYCH a K. KOBERNA. Looking for ugly ducklings: The role of the stability of BrdU-antibody complex and the improved method of the detection of DNA replication. PLOS One. 2017, 12(3), e0174893, ISSN 1932-6203, IF: 3.057, PMID: 28358913
JOUROVA, L., P. ANZENBACHER, B. LIŠKOVÁ, Z. RÁCOVÁ (MATUŠKOVÁ), P. HERMANOVA, T. HUDCOVIC, H. KOZAKOVA, L. HRNCIROVA a E. ANZENBACHEROVÁ. Colonization by non-pathogenic bacteria alters mRNA expression of cytochromes P450 in originally germ-free mice. Folia Microbiologica. 2017, 62(6), 463-469, ISSN 0015-5632 , IF: 1.335, PMID: 28337589
TICHÝ, M., S. SMOLEN, E. TLOUŠŤOVÁ, R. POHL, T. OŽDIAN, K. HEJTMÁNKOVÁ, B. LIŠKOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides. Journal of Medicinal Chemistry. 2017, 60(6), 2411-2424, ISSN 0022-2623, IF: 5.589, PMID: 28221790
ŠIDOVÁ, V., P. ZOUFALÝ, J. POKORNÝ, P. DŽUBÁK, M. HAJDÚCH, I. POPA a M. URBAN. Cytotoxic conjugates of betulinic acid and substituted triazoles prepared by Huisgen Cycloaddition from 30-azidoderivatives. PLOS One. 2017, 12(2), e0171621, ISSN 1932-6203 , IF: 3.057, PMID: 28158265
VOLLER, J., T. BERES, M. ZATLOUKAL, P. KAMINSKI, P. NIEMANN, K. DOLEZAL, P. DŽUBÁK, M. HAJDÚCH a M. STRNAD. The natural cytokinin 2OH3MeOBAR induces cell death by a mechanism that is different from that of the "classical" cytokinin ribosides. Phytochemistry. 2017, 136, 156-164, ISSN 0031-9422 , IF: 2.779, PMID: 28153445
BORKOVÁ, L., R. ADÁMEK, P. KALINA, P. DRAŠAR, P. DŽUBÁK, S. GURSKÁ, J. ŘEHULKA, M. HAJDÚCH, M. URBAN a J. ŠAREK. Synthesis and Cytotoxic Activity of Triterpenoid Thiazoles Derived from Allobetulin, Methyl Betulonate, Methyl Oleanonate, and Oleanonic Acid. ChemMedChem. 2017, 12(5), 390-398, ISSN 1860-7179 , IF: 2.980, PMID: 28084676
USSI, A.E., M. REBOLI, M. THORAT, F. BIETRIX, A. FAUVEL, M. HAJDÚCH, C. HILL, I. WALKER, M. VAN ENGLAND, J. CUZICK a G. MEIJER. Letter to the editor: Assessing opportunities for coordinated R&D in early cancer detection and management in Europe. International Journal of Cancer. 2016, 140, 1700-1701, ISSN 0020-7136 , IF: 6.513, PMID: 27943265
AGRAWAL, K., V. DAS, M. OTMAR, M. KRECMEROVA, P. DŽUBÁK a M. HAJDÚCH. Cell-based DNA demethylation detection system for screening of epigenetic drugs in 2D, 3D, and xenograft models. Cytometry A. 2016, -, -, ISSN 1552-4922 , IF: 3.222, PMID: 27911980
NAJDEKR, L., D. FRIEDECKÝ, R. TAUTENHAHN, T. PLUSKAL, J. WANG, Y. HUANG a T. ADAM. Influence of Mass Resolving Power in Orbital Ion-Trap Mass Spectrometry-Based Metabolomics. Analytical Chemistry. 2016, 88(23), 11429-11435, ISSN 0003-2700, IF: 6.320, PMID: 27809493
LITHWICK-YANAI, G., N. DROMI, A. SHTABSKY, S. MORGENSTERN, Y. STRENOV, M. FEINMESSER, V. KRAVTSOV, M. LEON, M. HAJDÚCH, S. ALI, C. VANDENBUSSCHE, C. ZHANG, L. LEIDER-TREJO, A. ZUBKOV, S. VOROBYOV, M. KUSHNIR, Y. GOREN, S. TABAK, E. KADOSH, H. BENJAMIN, T. SCHNITZER-PERLMAN, H. MARMOR, M. MOTIN, D. LEBANONY, S. KREDO-RUSSO, H. MITCHELL, M. NOLLER, A. SMITH, O. DATTNER, K. ASKHENAZI, M. SANDEN, K. BERLIN, D. BAR a E. MEIRI. Multicentre validation of a microRNA-based assay for diagnosing indeterminate thyroid nodules utilising fine needle aspirate smears. Journal of Clinical Pathology. 2017, 70(6), 500-507, ISSN 0021-9746 , IF: 2.912, PMID: 27798083
BÉRESOVÁ, L., E. VESELÁ, I. CHAMRAD, J. VOLLER, M. YAMADA, T. FÜRST, R. LENOBEL, K. CHROMÁ, J. GURSKÝ, K. KŘÍŽOVÁ, M. MISTRÍK a J. BÁRTEK. Role of DNA Repair Factor Xeroderma Pigmentosum Protein Group C in Response to Replication Stress As Revealed by DNA Fragile Site Affinity Chromatography and Quantitative Proteomics. Journal of Proteome Research. 2016, 15(12), 4505-4517, ISSN 1535-3893 , IF: 4.268, PMID: 27794614
DRÁBEK, J., M. SMOLIKOVA, R. KALENDAR, F. LOPES PINTO, P. PAVLOUSEK, K. KLEPARNIK a I. FREBORT. Design and validation of an STR hexaplex assay for DNA profiling of grapevine cultivars. Electrophoresis. 2016, 37(23-24), 3059-3067, ISSN 0173-0835 , IF: 2.744, PMID: 27696463
KISS, I., J. MLCOCHOVA, Z. BORTLICEK, A. POPRACH, J. DRÁBEK, P. VYCHYTILOVA-FALTEJSKOVA, M. SVOBODA, T. BUCHLER, S. BATKO, A. RYSKA, M. HAJDÚCH a O. SLABÝ. Efficacy and Toxicity of Panitumumab After Progression on Cetuximab and Predictive Value of MiR-31-5p in Metastatic Wild-type KRAS Colorectal Cancer Patients. Anticancer Research. 2016, 36(9), 7955-9, ISSN 0250-7005 , IF: 1.937, PMID: 27630355
SCHADICH, E., P. DŽUBÁK a M. HAJDÚCH. Role of Salmonella Typhi Vi Antigen and Secretory Systems on Immune Response. Current Pharmaceutical Design. 2016, 22(41), 6251-6260, ISSN 1381-6128, IF: 2.611, PMID: 27573929
JURÁŠEK, M., P. DŽUBÁK, S. RIMPELOVA, D. SEDLÁK, P. KONEČNÝ, I. FRYDRYCH, S. GURSKÁ, M. HAJDÚCH, K. BOGDANOVÁ, M. KOLÁŘ, T. MÜLLER, E. KMONICKOVA, T. RUML, J. HARMATHA a P. DRAŠAR. Trilobolide-steroid hybrids: Synthesis, cytotoxic and antimycobacterial activity. Steroids. 2017, 117(2017), 97-104, ISSN 0039-128X, IF: 2.513, PMID: 27543674
KLASKOVA, E., J. DRÁBEK, M. HOBZOVA, V. SMOLKA, M. SEDA, J. HYJÁNEK, R. SLAVKOVSKÝ, J. STRÁNSKÁ a M. PROCHAZKA. Significant phenotype variability of congenital central hypoventilation syndrome in a family with polyalanine expansion mutation of the PHOX2B gene. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(4), 495-498, ISSN 1213-8118 , IF: 0.894, PMID: 27485184
POLISHCHUK, P., O. TINKOV, T. KHRISTOVA, L. OGNICHENKO, A. KOSINSKAYA, A. VARNEK a V. KUZMIN. Structural and Physico-Chemical Interpretation (SPCI) of QSAR Models and Its Comparison with Matched Molecular Pair Analysis. Journal of Chemical Information and Modeling. 2016, -(-), -, ISSN 1549-9596, IF: 3.760, PMID: 27419846
JAROSOVA, M., J. VOLEJNÍKOVÁ, I. PORIZKOVA, M. HOLZEROVA, D. POSPÍŠILOVÁ, Z. NOVÁK, J. VRBKOVÁ a V. MIHÁL. Chromosomal aberrations in childhood acute lymphoblastic leukemia: 15-year single center experience. Cancer Genetics. 2016, 209(7-8), 340-347, ISSN 2210-7762, IF: 1.930, PMID: 27341996
KLIMENKO, K., V. KUZMIN, L. OGNICHENKO, L. GORB, M. SHUKLA, N. VINAS, E. PERKINS, P. POLISHCHUK, A. ARTEMENKO a J. LESZCZYNSKI. Novel enhanced applications of QSPR models: Temperature dependence of aqueous solubility. Journal of Computational Chemistry. 2016, 37(22), 2045-2051, ISSN 0192-8651 , IF: 3.229, PMID: 27338156
BORKOVÁ, L., S. GURSKÁ, P. DŽUBÁK, R. BURIÁNOVÁ, M. HAJDÚCH, J. ŠAREK, I. POPA a M. URBAN. Lupane and 18α-oleanane derivatives substituted in the position 2, their cytotoxicity and influence on cancer cells. European Journal of Medicinal Chemistry. 2016, 121, 120-131, ISSN 0223-5234 , IF: 4.519, PMID: 27236068
DAS, V., T. FÜRST, S. GURSKÁ, P. DŽUBÁK a M. HAJDÚCH. Reproducibility of Uniform Spheroid Formation in 384-Well Plates: The Effect of Medium Evaporation. Journal of Biomolecular Screening. 2016, 21(9), 923-30, ISSN 1087-0571 , IF: 2.444, PMID: 27226477
PLUHACEK, T., M. PETŘÍK, D. LUPTAKOVA, O. BENADA, A. PALYZOVA, K. LEMR a V. HAVLÍČEK. Aspergillus infection monitored by multimodal imaging in a rat model. Proteomics. 2016, 16(11-12), 1785-1792, ISSN 1615-9853 , IF: 4.041, PMID: 27060291
VOLEJNÍKOVÁ, J., V. BAJCIOVA, L. SULOVSKÁ, M. GEIEROVÁ, E. BURIANKOVA, M. JAROSOVA, M. HAJDÚCH, J. STERBA a V. MIHÁL. Bone marrow metastasis of malignant melanoma in childhood arising within a congenital melanocytic nevus. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(3), 456-460, ISSN 1213-8118 , IF: 0.894, PMID: 27049531
GILLILAND, C.T., D. ZUK, P. KOCIS, M. JOHNSON, S. HAY, M. HAJDÚCH, F. BIETRIX, G. AVERSA, C.P. AUSTIN a A.E. USSI. Putting translational science on to a global stage. Nature Reviews Drug Discovery. 2016, 15, 217-219, ISSN 1474-1776, IF: 57.000, PMID: 27032820
HRUBY, M., K. AGRAWAL, O. POLICIANOVA, J. BRUS, J. SKOPAL, P. SVEC, M. OTMAR, P. DŽUBÁK, P. STEPANEK a M. HAJDÚCH. Biodegradable system for drug delivery of hydrolytically labile azanucleoside drugs. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2016, 160(2), 222-230, ISSN 1213-8118 , IF: 0.894, PMID: 27003313
KALITA, O., R. TROJANEC, M. HOUDOVÁ MEGOVÁ , M. HAJDÚCH, M. VAVERKA, L. HRABALEK, M. ZLEVOROVA, J. DRÁBEK, L. TUČKOVÁ a J. VRBKOVÁ. Glioblastoma multiforme in patients with history of extracranial cancer: Case series. Clinical Neurology and Neurosurgery. 2016, 144(-), 39-43, ISSN 0303-8467, IF: 1.381, PMID: 26971293
SCHADICH, E., J. HLAVÁČ, T. VOLNÁ, L. VARANASI, M. HAJDÚCH a P. DŽUBÁK. Effects of Ginger Phenylpropanoids and Quercetin on Nrf2-ARE Pathway in Human BJ Fibroblasts and HaCaT Keratinocytes. BioMed Research International . 2016, 2016, 2016:2173275, ISSN 2314-6133, IF: 2.476, PMID: 26942188
VOLEJNÍKOVÁ, J., M. JAROSOVA, D. POSPÍŠILOVÁ, Z. NOVÁK, J. VRBKOVÁ, M. HAJDÚCH a V. MIHÁL. Treatment and prognosis of childhood acute lymphoblastic leukemia on protocols ALL-BFM 90, 95 and ALL IC-BFM 2002: a retrospective single-center study from Olomouc, Czech Republic. Neoplasma. 2016, 63(3), 456-61, ISSN 0028-2685, IF: 1.871, PMID: 26925793
KRYSKO, A., A. KORNYLOV, P. POLISHCHUK, G. SAMOYLENKO, O. KRYSKO, T. KABANOVA, V. KRAVTSOV, V. KABANOV, B. WICHER a S. ANDRONATI. Synthesis, biological evaluation and molecular docking studies of 2-piperazin-1-yl-quinazolines as platelet aggregation inhibitors and ligands of integrin alpha(IIb)beta(3). Bioorganic and Medicinal Chemistry Letters. 2016, 26(7), 1839-1843, ISSN 0960-894X, IF: 2.454, PMID: 26912112
ZHAI, C., G. FRANSSEN, M. PETŘÍK, P. LAVERMAN, D. SUMMER, C. RANGGER, R. HAUBNER, H. HAAS a C. DECRISTOFORO. Comparison of Ga-68-Labeled Fusarinine C-Based Multivalent RGD Conjugates and [68Ga]NODAGA-RGD-In Vivo Imaging Studies in Human Xenograft Tumors. Molecular Imaging and Biology. 2016, 18(5), 758-67, ISSN 1536-1632, IF: 3.466, PMID: 26905697
KOUDELÁKOVÁ, V., R. TROJANEC, J. VRBKOVÁ, S. DONEVSKA, K. BOUCHALOVÁ, M. KOLÁŘ, L. VARANASI a M. HAJDÚCH. Frequency of chromosome 17 polysomy in relation to CEP17 copy number in a large breast cancer cohort. Genes Chromosomes & Cancer. 2016, 55(5), 409-17, ISSN 1045-2257 , IF: 3.696, PMID: 26847577
DRÁBEK, J. Surmounting PCR challenge using Contradictory matrix from Theory of Inventive Problem Solving (TRIZ). SpringerPlus. 2016, 5(1), 1-6, ISSN 2193-1801 , IF: 1.130, PMID: 26835236
PERLÍKOVÁ, P., G. RYLOVÁ, P. NAUŠ, T. ELBERT, E. TLOUŠŤOVÁ, A. BOURDERIOUX, L. SLAVĚTÍNSKÁ, K. MOTYKA, D. DOLEŽAL, P. ZNOJEK, A. NOVÁ, M. HARVANOVÁ, P. DŽUBÁK, M. ŠILLER, J. HLAVÁČ, M. HAJDÚCH a M. HOCEK. 7-(2-Thienyl)-7-deazaadenosine (AB61), a new potent nucleoside cytostatic with a complex mode of action. Molecular Cancer Therapeutics. 2016, 15(5), 922-937, ISSN 1535-7163 , IF: 5.764, PMID: 26819331
LIGASOVÁ, A., R. LIBOSKA, D. FRIEDECKÝ, K. MIČOVÁ, T. ADAM, T. OŽDIAN, I. ROSENBERG a K. KOBERNA. Dr Jekyll and Mr Hyde: A Strange Case of 5-Ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine. Open Biology. 2016, 6: 150172, 1-11, ISSN 2046-2441, IF: 3.481, PMID: 26740587
HEZOVA, R., A. KOVARIKOVA, J. SROVNAL, M. ZEMANOVÁ, T. HARUSTIAK, J. EHRMANN, M. HAJDÚCH, M. SACHLOVA, M. SVOBODA a O. SLABÝ. MiR-205 functions as a tumor suppressor in adenocarcinoma and an oncogene in squamous cell carcinoma of esophagus. Tumor Biology. 2015, 37(6), 8007-18, ISSN 1010-4283 , IF: 2.926, PMID: 26711784
VYLICILOVA, H., V. HUSICKOVA, L. SPICHAL, J. SROVNAL, K. DOLEZAL, O. PLIHAL a L. PLÍHALOVÁ. C2-substituted aromatic cytokinin sugar conjugates delay the onset of senescence by maintaining the activity of the photosynthetic apparatus. Phytochemistry. 2015, 122(-), 22-33, ISSN 0031-9422, IF: 2.779, PMID: 26706318
PFISTER, J., D. SUMMER, C. RANGGER, M. PETŘÍK, E. VON GUGGENBERG, P. MINAZZI, G. GIOVENZANA, L. ALOJ a C. DECRISTOFORO. Influence of a novel, versatile bifunctional chelator on theranostic properties of a minigastrin analogue. European Journal of Nuclear Medicine and Molecular Imaging Research. 2015, 5(74), 1-11, ISSN 2191-219X, IF: 1.761, PMID: 26669693
SULOVSKÁ, L., D. HOLUB, Z. ŽIDOVÁ, M. DIVOKÁ, M. HAJDÚCH, V. MIHÁL, J. VRBKOVÁ, M. HORVÁTHOVÁ a D. POSPÍŠILOVÁ. Characterization of iron metabolism and erythropoiesis in erythrocyte membrane defects and thalassemia traits. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2015, 160(2), 231-237, ISSN 1213-8118 , IF: 0.924, PMID: 26592557
NAUŠ, P., O. CALETKOVÁ, P. PERLÍKOVÁ, L. SLAVĚTÍNSKÁ, E. TLOUŠŤOVÁ, J. HODEK, J. WEBER, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and biological profiling of 6-or 7-(het)aryl-7-deazapurine 4 '-C-methylribonucleosides. Bioorganic and Medicinal Chemistry. 2015, 23(23), 7422-7438, ISSN 0968-0896 , IF: 2.923, PMID: 26558518
BRAUER, R., J. TURECKOVA, I. KANCHEV, M. KHOYLOU, J. ŠKARDA, J. PROCHAZKA, F. SPOUTIL, I.M. BECK, O. ŽBODÁKOVÁ, P. KASPAREK, V. KORINEK, K. CHALUPSKÝ, T. KARHU, K.H. HERZIG, M. HAJDÚCH, M. GREGOR a R. SEDLÁČEK. MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function. Mucosal Immunology. 2016, 9(4), 974-985, ISSN 1933-0219, IF: 7.478, PMID: 26555704
SOURAL, M., J. HODOŇ, N.J. DICKINSON, V. ŠIDOVÁ, S. GURSKÁ, P. DŽUBÁK, M. HAJDÚCH, J. ŠAREK a M. URBAN. Preparation of Conjugates of Cytotoxic Lupane Triterpenes with Biotin. Bioconjugate Chemistry. 2015, 26(12), 2563-70, ISSN 1043-1802, IF: 4.818, PMID: 26537839
PETŘÍK, M., C. ZHAI, Z. NOVÝ, L. URBANEK, H. HAAS a C. DECRISTOFORO. In vitro and in vivo comparison of selected Ga-68 and Zr-89 labelled siderophores. Molecular Imaging and Biology. 2015, 18(3), 344-52, ISSN 1860-2002, IF: 2.569, PMID: 26424719
POL, J., H. FALTYSKOVA, L. KRASNY, M. VOLNY, O. VLACIL, M. HAJDÚCH, K. LEMR a V. HAVLICEK. Age-related changes in the lateral lipid distribution in a human lens described by mass spectrometry imaging. European Journal of Mass Spectrometry . 2015, 21(3), 297-303, ISSN 1469-0667, IF: 1.011, PMID: 26307709
SURINOVA, S., M. CHOI, S. TAO, P.J. SCHÜFFLER, C.Y.. CHANG, T. CLOUGH, K. VYSLOUŽIL, M. KHOYLOU, J. SROVNAL, Y. LIU, M. MATONDO, R. HÜTTENHAIN, H. WEISSER, J.M. BUHMANN, M. HAJDÚCH, H. BRENNER, O. VITEK a R. AEBERSOLD. Prediction of colorectal cancer diagnosis based on circulating plasma proteins. EMBO Molecular Medicine. 2015, 7(9), 1166-1178, ISSN 1757-4676 , IF: 9.547, PMID: 26253081
SURINOVA, S., L. RADOVÁ, M. CHOI, J. SROVNAL, H. BRENNER, O. VITEK, M. HAJDÚCH a R. AEBERSOLD. Non-invasive prognostic protein biomarker signatures associated with colorectal cancer. EMBO Molecular Medicine. 2015, 7(9), 1153-1165, ISSN 1757-4676, IF: 9.547, PMID: 26253080
LIGASOVÁ, A., R. LIBOSKA, I. ROSENBERG a K. KOBERNA. The Fingerprint of Anti-Bromodeoxyuridine Antibodies and Its Use for the Assessment of Their Affinity to 5-Bromo-2'-Deoxyuridine in Cellular DNA under Various Conditions. PLOS One. 2015, 10(7), e0132393, ISSN 1932-6203, IF: 3.057, PMID: 26161977
KOUDELÁKOVÁ, V., J. BERKOVCOVÁ, R. TROJANEC, J. VRBKOVÁ, L. RADOVÁ, J. EHRMANN, Z. KOLÁŘ, B. MELICHAR a M. HAJDÚCH. Evaluation of HER2 Gene Status in Breast Cancer Samples with Indeterminate Fluorescence in Situ Hybridization by Quantitative Real-Time PCR Method. Journal of Molecular Diagnostic. 2015, 17(4), 446-455, ISSN 1525-1578, IF: 5.201, PMID: 25956448
BORKOVÁ, L., L. JASILKOVA, J. ŘEHULKA, K. FRISONSOVA, M. URBAN, I. FRYDRYCH, I. POPA, M. HAJDÚCH, N.J. DICKINSON, M. VLK, P. DŽUBÁK a J. ŠAREK. Synthesis of cytotoxic 2,2-difluoroderivatives of dihydrobetulinic acid and allobetulin and study of their impact on cancer cells. European Journal of Medicinal Chemistry. 2015, 96(-), 482-490, ISSN 0223-5234, IF: 3.902, PMID: 25942059
ZHAI, C., D. SUMMER, C. RANGGER, G. FRANSSEN, P. LAVERMAN, H. HAAS, M. PETŘÍK, R. HAUBNER a C. DECRISTOFORO. Novel Bifunctional Cyclic Chelator for (89)Zr Labeling-Radiolabeling and Targeting Properties of RGD Conjugates. Molecular Pharmaceutics. 2015, 12(6), 2142-2150, ISSN 1543-8384, IF: 4.342, PMID: 25941834
HEZOVA, R., A. KOVARIKOVA, J. SROVNAL, M. ZEMANOVÁ, T. HARUSTIAK, J. EHRMANN, M. HAJDÚCH, M. SVOBODA, M. SACHLOVA a O. SLABÝ. Diagnostic and prognostic potential of miR-21, miR-29c, miR-148 and miR-203 in adenocarcinoma and squamous cell carcinoma of esophagus. Diagnostic Pathology. 2015, 10(-), Article Number: 42, ISSN 1746-1596, IF: 1.895, PMID: 25928282
KAPLANEK, R., M. JAKUBEK, J. RAK, Z. KEJIK, M. HAVLIK, B.. DOLENSKY, I. FRYDRYCH, M. HAJDÚCH, M. KOLÁŘ, K. BOGDANOVÁ, J. KRALOVA, P. DŽUBÁK a V. KRAL. Caffeine-hydrazones as anticancer agents with pronounced selectivity toward T-lymphoblastic leukaemia cells. Bioorganic Chemistry. 2015, 60(-), 19-29, ISSN 0045-2068, IF: 2.252, PMID: 25912310
DAS, V., F. BRUZZESE, P. KONEČNÝ, F. IANNELLI, A. BUDILLON a M. HAJDÚCH. Pathophysiologically relevant in vitro tumor models for drug screening. Drug Discovery Today. 2015, 20(7), 848-55, ISSN 1359-6446, IF: 5.625, PMID: 25908576
MALNUIT, V., L. SLAVĚTÍNSKÁ, P. NAUŠ, P. DŽUBÁK, M. HAJDÚCH, J. STOLAŘÍKOVÁ, J. SNÁŠEL, I. PICHOVÁ a M. HOCEK. 2-Substituted 6-(Het)aryl-7-deazapurine Ribonucleosides: Synthesis, Inhibition of Adenosine Kinases, and Antimycobacterial Activity. ChemMedChem. 2015, 10(6), 1079-1093, ISSN 1860-7179, IF: 2.980, PMID: 25882678
NAJDEKR, L., A. GARDLO, L. MÁDROVÁ, D. FRIEDECKÝ, H. JANEČKOVÁ, E. CORREA, R. GOODACRE a T. ADAM. Oxidized phosphatidylcholines suggest oxidative stress in patients with medium-chain acyl-CoA dehydrogenase deficiency. Talanta. 2015, 139(2015), 62-66, ISSN 0039-9140, IF: 4.035, PMID: 25882409
SLABÝ, O., J. SROVNAL, L. RADOVÁ, J. GREGAR, J. JURACEK, P. LUŽNÁ, M. SVOBODA, M. HAJDÚCH a J. EHRMANN. Dynamic changes in microRNA expression profiles reflect progression of Barrett's esophagus to esophageal adenocarcinoma. Carcinogenesis. 2015, 36(5), 521-527, ISSN 0143-3334, IF: 4.874, PMID: 25784377
TRIZULJAK, J., J. SROVNAL, K. PLEVOVA, Y. BRYCHTOVA, L. SEMERAD, D. BAKEŠOVÁ, E. LETALOVA, A. BENEDÍKOVÁ, J. MAYER, M. HAJDÚCH, S. POSPISILOVA a M. DOUBEK. Analysis of Prognostic Significance of Merkel Cell Polyomavirus in Chronic Lymphocytic Leukemia. Clinical Lymphoma Myeloma & Leukemia. 2015, 15(7), 439-442, ISSN 2152-2669, IF: 2.316, PMID: 25758600
KAPLANEK, R., M. HAVLIK, B.. DOLENSKY, J. RAK, P. DŽUBÁK, P. KONEČNÝ, M. HAJDÚCH, J. KRALOVA a V. KRAL. Synthesis and biological activity evaluation of hydrazone derivatives based on a Troger's base skeleton. Bioorganic and Medicinal Chemistry. 2015, 23(7), 1651-1659, ISSN 0968-0896, IF: 2.923, PMID: 25737088
LIGASOVÁ, A., D. STRUNIN, D. FRIEDECKÝ, T. ADAM a K. KOBERNA. A fatal combination: a thymidylate synthase inhibitor with DNA damaging activity. PLOS One. 2015, 10(2), 1-21, ISSN 1932-6203, IF: 3.057, PMID: 25671308
DAS, V., J. DVOŘANOVÁ ŠTĚPÁNKOVÁ, M. HAJDÚCH a J.H. MILLER. Role of tumor hypoxia in acquisition of resistance to microtubule-stabilizing drugs. Biochimica et Biophysica Acta Reviews on Cancer. 2015, 1855(2), 172-182, ISSN 0304-419X, IF: 7.841, PMID: 25662312
STRÁNSKÁ, J., S. JANČÍK, R. SLAVKOVSKÝ, V. HOLINKOVÁ, M. RABČANOVÁ, P. VOJTA, M. HAJDÚCH a J. DRÁBEK. Whole genome amplification induced bias in the detection of KRAS-mutated cell populations during colorectal carcinoma tissue testing. Electrophoresis. 2015, 36(6), 937-40, ISSN 0173-0835, IF: 2.482, PMID: 25655305
HAAS, H., M. PETŘÍK a C. DECRISTOFORO. An iron-mimicking Trojan horse entering fungi - has the time come for molecular imaging of fungal infections?. PLOS Pathogens. 2015, 11(1), 1-7, ISSN 1553-7366, IF: 7.003, PMID: 25634225
BRIZA, T., J. KRALOVA, B.. DOLENSKY, S. RIMPELOVA, Z. KEJIK, T. RUML, M. HAJDÚCH, P. DŽUBÁK, I. MIKULA, P. MARTASEK, P. POUCKOVA a V. KRAL. Striking antitumor activity of a methinium system with incorporated quinoxaline unit obtained by spontaneous cyclization. Chembiochem. 2015, 16(4), 555-558, ISSN 1439-4227, IF: 2.850, PMID: 25630657
BOUCHALOVÁ, K., M. SVOBODA, G. KHARAISHVILI, J. VRBKOVÁ, J. BOUCHAL, R. TROJANEC, V. KOUDELÁKOVÁ, L. RADOVÁ, K. CWIERTKA, M. HAJDÚCH a Z. KOLÁŘ. BCL2 is an independent predictor of outcome in basal-like triple-negative breast cancers treated with adjuvant anthracycline-based chemotherapy. Tumor Biology. 2015, 36(6), 4243-52, ISSN 1010-4283 , IF: 2.926, PMID: 25616695
JANEČKOVÁ, H., A. KALIVODOVÁ, L. NAJDEKR, D. FRIEDECKÝ, K. HRON, P. BRUHEIM a T. ADAM. Untargeted metabolomic analysis of urine samples in the diagnosis of some inherited metabolic disorders. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2015, 159(4), 582-585, ISSN 1213-8118, IF: 0.924, PMID: 25482736
RYLOVÁ, G., T. OŽDIAN, L. VARANASI, M. SOURAL, J. HLAVÁČ, D. HOLUB, P. DŽUBÁK a M. HAJDÚCH. Affinity-Based Methods in Drug-Target Discovery. Current Drug Targets. 2015, 16(1), 60-76, ISSN 1389-4501, IF: 3.029, PMID: 25410410
PETŘÍK, M., A. VLČKOVÁ, Z. NOVÝ, L. URBANEK, H. HAAS a C. DECRISTOFORO. Selected 68Ga-siderophores versus 68Ga-colloid and 68Ga-citrate: biodistribution and small animal imaging in mice. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2015, 159(1), 60-66, ISSN 1213-8118, IF: 0.924, PMID: 25363728
ŠÁNA, J., L. RADOVÁ, R. LAKOMÝ, L. KREN, P. FADRUS, M. SMRCKA, A. BESSE, J. NEKVINDOVA, M. HERMANOVA, R.. JANCALEK, M. SVOBODA, M. HAJDÚCH, P. SLAMPA, R. VYZULA a O. SLABÝ. Risk Score based on microRNA expression signature is independent prognostic classifier of glioblastoma patients. Carcinogenesis. 2014, 35(12), 2756-62, ISSN 0143-3334, IF: 5.334, PMID: 25322872
DRÁBEK, J. a G. CEREDA. Interpreting noninvasive prenatal paternity tests. Genetics in Medicine. 2014, 16(10), 793-794, ISSN 1098-3600, IF: 7.329, PMID: 25290259
SNÁŠEL, J., P. NAUŠ, J. DOSTÁL, A. HNÍZDA, J. FANFRLÍK, J. BRYNDA, A. BOURDERIOUX, M. DUŠEK, H. DVOŘÁKOVÁ, J. STOLAŘÍKOVÁ, H. ZÁBRANSKÁ, R. POHL, P. KONEČNÝ, P. DŽUBÁK, I. VOTRUBA, M. HAJDÚCH, P. ŘEZÁČOVÁ, V. VEVERKA, M. HOCEK a I. PICHOVÁ. Structural Basis for Inhibition of Mycobacterial and Human Adenosine Kinase by 7-Substituted 7-(Het)aryl-7-deazaadenine Ribonucleosides. Journal of Medicinal Chemistry. 2014, 57(20), 8268-8279, ISSN 0022-2623, IF: 5.447, PMID: 25259627
HOUDOVÁ MEGOVÁ , M., J. DRÁBEK, V. KOUDELÁKOVÁ, R. TROJANEC, O. KALITA a M. HAJDÚCH. Isocitrate dehydrogenase 1 and 2 mutations in gliomas. Journal of Neuroscience Research. 2014, 92(12), 1611-1620, ISSN 0360-4012, IF: 2.594, PMID: 25078896
NOVÝ, Z., A. LAZNICKOVA, J. MANDIKOVA, P. BARTA, M. LAZNICEK a F. TREJTNAR. The effect of chelator type on in vitro receptor binding and stability in 177Lu-labeled cetuximab and panitumumab. Journal of Labelled Compounds & Radiopharmaceuticals. 2014, 57(7), 448-452, ISSN 1099-1344, IF: 1.273, PMID: 24889367
KANAGARATHAM, C., A. KALIVODOVÁ, L. NAJDEKR, D. FRIEDECKÝ, T. ADAM, M. HAJDÚCH, J.B. DE SANCTIS a D. RADZIOCH. Fenretinide prevents inflammation and airway hyperresponsiveness in a mouse model of allergic asthma. American Journal of Respiratory Cell and Molecular Biology. 2014, 51(6), 783-92, ISSN 1535-4989, IF: 3.985, PMID: 24885263
LUKÁŠ, J., J. DRÁBEK, B. DUDESEK, P. VAZAN, J. STRÁNSKÁ, S. JANČÍK, M. MACKOVA, M. SYRUCEK, D. LUKAS, J. DUSKOVA a P. DUNDR. Correlation among the BRAF Gene Mutation Status, Clinicopathological Features of Primary Tumour, and Lymph Node Metastasizing of Papillary Thyroid Carcinoma. Experimental and Clinical Endocrinology and Diabetes. 2014, 122(5), 268-272, ISSN 0947-7349, IF: 1.555, PMID: 24839220
MATTOVA, J., P. POUCKOVA, J. KUCKA, M. SKODOVA, M. VETRIK, P. STEPANEK, P. URBANEK, M. PETŘÍK, Z. NOVÝ a M. HRUBY. Chelating polymeric beads as potential therapeutics for Wilson's disease. European Journal of Pharmaceutical Sciences. 2014, 62(-), 1-7, ISSN 0928-0987, IF: 3.350, PMID: 24815561
DAS, V., A. KANAKKANTHARA, A. CHAN a J.H. MILLER. Potential role of tubulin tyrosine ligase-like enzymes in tumorigenesis and cancer cell resistance. Cancer Letters. 2014, 350(1-2), 1-4, ISSN 0304-3835, IF: 5.621, PMID: 24814394
DAS, V., D.A. SIM a J.H. MILLER. Effect of taxoid and nontaxoid site microtubule-stabilizing agents on axonal transport of mitochondria in untransfected and ECFP-htau40-transfected rat cortical neurons in culture. Journal of Neuroscience Research. 2014, 92(9), 1155-1166, ISSN 0360-4012, IF: 2.594, PMID: 24788108
POSPÍŠILOVÁ, D., D. HOLUB, Z. ŽIDOVÁ, L. SULOVSKÁ, J. HOUDA, V. MIHÁL, I. HADAČOVÁ, L. RADOVÁ, P. DŽUBÁK, M. HAJDÚCH, V. DIVOKÝ a M. HORVÁTHOVÁ. Hepcidin levels in Diamond-Blackfan anemia reflect erythropoietic activity and transfusion dependency. Haematologica. 2014, 99(7), e118-121, ISSN 0390-6078, IF: 5.814, PMID: 24727814
RANC, V., Z. MARKOVÁ, M. HAJDÚCH, R. PRUCEK, L. KVÍTEK, J. KAŠLÍK, K. ŠAFÁŘOVÁ a R. ZBOŘIL. Magnetically Assisted Surface-Enhanced Raman Scattering Selective Determination of Dopamine in an Artificial Cerebrospinal Fluid and a Mouse Striatum Using Fe3O4/Ag Nanocomposite. Analytical Chemistry. 2014, 86(6), 2939-2946, ISSN 0003-2700, IF: 5.636, PMID: 24555681
KALLIFATIDIS, B., J. BOROVICKA, J. STRÁNSKÁ, J. DRÁBEK a D. MILLS. Fluorescent Random Amplified Microsatellites (F-RAMS) analysis of mushrooms as a forensic investigative tool. Forensic Science International: Genetics. 2014, 9(-), 25-32, ISSN 1872-4973, IF: 4.604, PMID: 24528576
NAUŠ, P., O. CALETKOVÁ, P. KONEČNÝ, P. DŽUBÁK, K. BOGDANOVÁ, M. KOLÁŘ, J. VRBKOVÁ, L. SLAVĚTÍNSKÁ, E. TLOUŠŤOVÁ, P. PERLÍKOVÁ, M. HAJDÚCH a M. HOCEK. Synthesis, cytostatic, antimicrobial, and anti-HCV activity of 6-substituted 7-(het)aryl-7-deazapurine ribonucleosides. Journal of Medicinal Chemistry. 2014, 57(3), 1097-1110, ISSN 0022-2623, IF: 5.447, PMID: 24397620
HRABALEK, L., O. KALITA, M. VAVERKA, M. HAJDÚCH, M. ZLEVOROVA, J. EHRMANN, E. CECHAKOVA, M. ADAMUS, V. NOVAK a K. LANGOVÁ. Resection versus biopsy of glioblastomas in eloquent brain areas. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2015, 159(1), 150-155, ISSN 1213-8118, IF: 0.924, PMID: 23945847
RANC, V., J. SROVNAL, L. KVÍTEK a M. HAJDÚCH. Discrimination of circulating tumor cells of breast cancer and colorectal cancer from normal human mononuclear cells using Raman spectroscopy. Analyst. 2013, 138(20), 5983-5988, ISSN 0003-2654, IF: 3.906, PMID: 23945652
LIGASOVÁ, A., D. STRUNIN a K. KOBERNA. A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA. PLOS One. 2013, 8(6), 1-6, ISSN 1932-6203, IF: 3.534, PMID: 23825578
KOUDELÁKOVÁ, V., M. MEGOVÁ, R. TROJANEC, J. DRÁBEK a M. HAJDÚCH. Non-small cell lung cancer - genetic predictors. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2013, 157(2), 125-136, ISSN 1213-8118, IF: 1.661, PMID: 23733083
CHUDÁČEK, J., T. BOHANES, J. KLEIN, A. BENEDÍKOVÁ, J. SROVNAL, M. SZKORUPA, P. SKALICKÝ, J. ŠKARDA, M. HAJDÚCH a C. NEORAL. Detection of minimal residual disease in lung cancer. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2014, 158(2), 189-193, ISSN 1213-8118, IF: 1.200, PMID: 23558472
FILIPCIKOVA, R., I. OBORNA, J. BREZINOVA, J. NOVOTNY, G. WOJEWODKA, J.B. DE SANCTIS, L. RADOVÁ, M. HAJDÚCH a D. RADZIOCH. Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2015, 159(1), 77-82, ISSN 1213-8118, IF: 0.924, PMID: 23446211
TYLEČKOVÁ, J., R. HRABAKOVA, K. MAIRYCHOVÁ, P. HALADA, L. RADOVÁ, P. DŽUBÁK, M. HAJDÚCH, S.J. GADHER a H. KOVÁŘOVÁ. Cancer Cell response to Anthracyclines Effects: Mysteries of the Hidden Proteins Associated with These Drugs. International Journal of Molecular Sciences. 2012, 2012(13), 15536-15564, ISSN 1422-0067, IF: 2.464, PMID: 23443080
HÜTTENHAIN, R., S. SURINOVA, R. OSSOLA, Z. SUN, D. CAMPBELL, F. CERCIELLO, R. SCHIESS, D. BAUSCH-FLUCK, G. ROSENBERGER, J. CHEN, O. RINNER, U. KUSEBAUCH, M. HAJDÚCH, R.L. MORITZ, B. WOLLSCHEID a R. AEBERSOLD. N-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications. Molecular & Cellular Proteomics. 2013, 12(4), 1005-1016, ISSN 1535-9476, IF: 7.254, PMID: 23408683
BALIK, V., J. SROVNAL, I. SULLA, O. KALITA, T. FOLTANOVÁ, M. VAVERKA, L. HRABALEK a M. HAJDÚCH. MEG3: a novel long noncoding potentially tumour-suppressing RNA in meningiomas. Journal of Neuro-Oncology. 2013, 112(1), 1-8, ISSN 0167-594X, IF: 2.787, PMID: 23307326
JURÁŠEK, M., P. DŽUBÁK, D. SEDLÁK, H. DVOŘÁKOVÁ, M. HAJDÚCH, P. BARTŮNĚK a P. DRAŠAR. Preparation, preliminary screening of new types of steroid conjugates and their activities on steroid receptors. Steroids. 2013, 78(-), 356-361, ISSN 0039-128X, IF: 2.716, PMID: 23291595
HRABAKOVA, R., M. KOLLAREDDY, J. TYLEČKOVÁ, P. HALADA, M. HAJDÚCH, S.J. GADHER a H. KOVÁŘOVÁ. Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy. Journal of Proteome Research. 2013, 12(1), 455-469, ISSN 1535-3893, IF: 5.001, PMID: 23151231
LUKÁŠ, J., J. DRÁBEK, D. LUKAS a J. GATEK. The epidemiology of thyroid cancer in the Czech Republic in comparison with other countries. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2013, 157(3), 266-275, ISSN 1213-8118, IF: 1.661, PMID: 23132514
SPENEROVA, M., P. DŽUBÁK, J. SROVNAL, L. RADOVÁ, R. BURIÁNOVÁ, P. KONEČNÝ, S. ŠÁLKOVÁ, Z. NOVÁK, D. POSPÍŠILOVÁ, J. STARÝ, B.. BLAZEK, J. HAK, T. VOTAVA, P. TIMR, E. KAISEROVA, E. BUBANSKA, V. MIHÁL a M. HAJDÚCH. Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistence in acute childhood lymphoblastic leukemia. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2014, 158(3), 422-427, ISSN 1213-8118, IF: 1.200, PMID: 23128824
HAVLÍK, R., J. SROVNAL, D. KLOS, A. BENEDÍKOVÁ, M. LOVEČEK, M. GHOTHIM, D. CAHOVÁ, C. NEORAL a M. HAJDÚCH. Occult tumour cells in peritoneal lavage are a negative prognostic factor in pancreatic cancer. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2013, 157(3), 233-238, ISSN 1213-8118, IF: 1.661, PMID: 23128819
PETŘÍK, M., H. HAAS, P. LAVERMAN, M. SCHRETTL, G. FRANSSEN, M. BLATZER a C. DECRISTOFORO. 68Ga-Triacetylfusarinine C and 68Ga-Ferrioxamine E for Aspergillus Infection Imaging: Uptake Specificity in Various Microorganisms. Molecular Imaging and Biology. 2014, 16(1), 102-108, ISSN 1536-1632, IF: 2.774, PMID: 23102540
KNETSCH, P.A., M. PETŘÍK, C. RANGGER, G. SEIDEL, H.J. PIETZSCH, I. VIRGOLINI, C. DECRISTOFORO a R. HAUBNER. [(68)Ga]NS(3)-RGD and [(68)Ga] Oxo-DO3A-RGD for imaging α(v)β(3) integrin expression: synthesis, evaluation, and comparison. Nuclear Medicine and Biology. 2013, 40(1), 65-72, ISSN 0969-8051, IF: 2.408, PMID: 23102540
JIROUŠKOVÁ, M., O. ŽBODÁKOVÁ, M. GREGOR, K. CHALUPSKÝ, L. SARNOVÁ, M. HAJDÚCH, J. EHRMANN, M. JIRKOVSKÁ a R. SEDLÁČEK. Hepatoprotective Effect of MMP-19 Deficiency in a Mouse Model of Chronic Liver Fibrosis. PLOS One. 2012, 7(10), 1-10, ISSN 1932-6203, IF: 3.730, PMID: 23056273
JANČÍK, S., J. DRÁBEK, J. BERKOVCOVÁ, Y. XU, M. STAŇKOVÁ, J. KLEIN, V. KOLEK, J. ŠKARDA, T. TICHÝ, I. GRYGÁRKOVÁ, D. RADZIOCH a M. HAJDÚCH. A comparison of Direct sequencing, Pyrosequencing, High resolution melting analysis, TheraScreen DxS, and the K-ras StripAssay for detecting KRAS mutations in non small cell lung carcinomas. Journal of Experimental & Clinical Cancer Research. 2012, 31(1), 79, ISSN 1756-9966, IF: 3.066, PMID: 22995035
HRADILOVÁ, L., M. POLÁKOVÁ, B. DVOŘÁKOVÁ, M. HAJDÚCH a L. PETRUŠ. Synthesis and cytotoxicity of some D-mannose clil conjugates with aminobenzoic acid derivatives. Carbohydrate Research. 2012, 2012(361), 1-6, ISSN 0008-6215, IF: 2.044, PMID: 22960207
GRELL, P., P. FABIAN, M. KHOYLOU, L. RADOVÁ, O. SLABÝ, R. HRSTKA, R. VYZULA, M. HAJDÚCH a M. SVOBODA. Akt expression and compartmentalization in prediction of clinical outcome in HER2-positive metastatic breast cancer patients treated with trastuzumab. International Journal of Oncology. 2012, 41(4), 1204-1212, ISSN 1019-6439, IF: 2.657, PMID: 22842582
SMILEK, P., J. NEUWIRTHOVA, J. JARKOVSKÝ, L. DUŠEK, J. ROTTENBERG, R. KOSTŘICA, J. SROVNAL, M. HAJDÚCH, J. DRÁBEK a J. KLOZAR. Epidermal growth factor receptor (EGFR) expression and mutations in the EGFR signaling pathway in correlation with anti-EGFR therapy in head and neck squamous cell carcinomas. Neoplasma. 2012, 59(5), 508-515, ISSN 0028-2685, IF: 1.547, PMID: 22668015
URBAN, M., M. VLK, P. DŽUBÁK, M. HAJDÚCH a J. ŠAREK. Cytotoxic heterocyclic triterpenoids derived from betulin and betulinic acid. Bioorganic & Medicinal Chemistry. 2012, 20(11), 3666-3674, ISSN 0968-0896, IF: 2.903, PMID: 22551630
PETŘÍK, M., A. SCHUESSELE, S. PERKHOFER, C. LASS-FLÖRL, D. BECKER a C. DECRISTOFORO. Microbial challenge tests on nonradioactive TiO2-based 68Ge/68Ga generator columns. Nuclear Medicine Communications. 2012, 33(8), 819-823, ISSN 0143-3636, IF: 1.379, PMID: 22546876
PETŘÍK, M., G. FRANSSEN, H. HAAS, P. LAVERMAN, C. HÖRTNAGL, M. SCHRETTL, A. HELBOK, C. LASS-FLÖRL a C. DECRISTOFORO. Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging. European Journal of Nuclear Medicine and Molecular Imaging. 2012, 39(7), 1175-1183, ISSN 1619-7070, IF: 5.114, PMID: 22526953
ČÍŽKOVÁ, M., K. BOUCHALOVÁ, D. FRIEDECKÝ, A. POLYNKOVA, A. JANOŠŤÁKOVÁ, L. RADOVÁ, K. CWIERTKA, R. TROJANEC, M. ZEZULOVÁ, M. ZLEVOROVA, M. HAJDÚCH a B. MELICHAR. High lapatinib plasma levels in breast cancer patients: risk or benefit?. Tumori. 2012, 98(1), 162-165, ISSN 0300-8916, IF: 0.922, PMID: 22495718
KOLLAREDDY, M., D. ZHELEVA, P. DŽUBÁK, P.S. BRAHMKSHATRIYA, M. LEPSIK a M. HAJDÚCH. Aurora kinase inhibitors: Progress towards the clinic. Investigational New Drugs. 2012, 30(6), 2411-2432, ISSN 0167-6997, IF: 3.498, PMID: 22350019
LAKOMÝ, R., J. ŠÁNA, S. HANKEOVÁ, P. FADRUS, L. KREN, E. LZICAROVA, M. SVOBODA, H. DOLEZELOVA, M. SMRCKA, R. VYZULA, M. HAJDÚCH a O. SLABÝ. MiR-195, miR-196b, miR-181c, miR-21 expression levels and O-6-methylguanine-DNA methyltransferase methylation status are associated with clinical outcome in glioblastoma patients. Cancer Science. 2011, 102(12), 2186-2190, ISSN 1347-9032, IF: 3.325, PMID: 21895872
BRULÍKOVÁ, L., P. DŽUBÁK, M. HAJDÚCH a J. HLAVÁČ. Synthesis of Various 5-Alkoxymethyluracil Analogues and Structure-Cytotoxic Activity Relationship Study. Carbohydrate Research. 2011, 346(14), 2136-2144, ISSN 0008-6215, IF: 2.332, PMID: 21864833
BOURDERIOUX, A., P. NAUŠ, P. PERLÍKOVÁ, R. POHL, I. PICHOVÁ, I. VOTRUBA, P. DŽUBÁK, P. KONEČNÝ, M. HAJDÚCH, K.M. STRAY, T. WANG, A.S. RAY, J.Y. FENG, G. BIRKUS, T. CIHLÁŘ a M. HOCEK. Synthesis and Significant Cytostatic Activity of 7-Hetaryl-7-deazaadenosines. Journal of Medicinal Chemistry. 2011, 54(15), 5498-5507, ISSN 0022-2623, IF: 5.248, PMID: 21711054
ŠÁNA, J., M. HAJDÚCH, R. VYZULA a O. SLABÝ. MicroRNAs and glioblastoma: roles in core signaling pathways and potential clinical implications. Journal of Cellular and Molecular Medicine. 2011, 15(8), 1636-1644, ISSN 1582-1838, IF: 4.125, PMID: 21435175
JORDA, R., L. HAVLICEK, I.W. MCNAE, M.D. WALKINSHAW, J. VOLLER, A. STURC, J. NAVRATILOVA, M. KUZMA, M. MISTRÍK, J. BÁRTEK, M. STRNAD a V. KRYŠTOF. Pyrazolo[4,3-d]pyrimidine Bioisostere of Roscovitine: Evaluation of a Novel Selective Inhibitor of Cyclin-Dependent Kinases with Antiproliferative Activity. Journal of Medicinal Chemistry. 2011, 54(8), 2980-2993, ISSN 0022-2623, IF: 5.248, PMID: 21417417
BOUCHALOVÁ, K., M. ČÍŽKOVÁ, K. CWIERTKA, R. TROJANEC, D. FRIEDECKÝ a M. HAJDÚCH. Lapatinib in breast cancer - the predictive significance of HER1 (EGFR), HER2, PTEN and PIK3CA genes and lapatinib plasma level assessment. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2010, 154(4), 281-288, ISSN 1213-8118, IF: 0.716, PMID: 21293538
SOURAL, M., J. HLAVÁČ, P. FUNK, P. DŽUBÁK a M. HAJDÚCH. 2-Phenylsubstituted-3-Hydroxyquinolin-4(1H)-one-Carboxamides: Structure-Cytotoxic Activity Relationship Study. ACS Combinatorial Science. 2011, 13(1), 39-44, ISSN 1520-4766, IF: 3.450, PMID: 21247123
SKALNIKOVA, H., J. MARTINKOVA, R. HRABAKOVA, P. HALADA, M. DZIECHCIARKOVÁ, M. HAJDÚCH, S.J. GADHER, A. HAMMAR, D. ENETOFT, A. EKEFJARD, O. FORSSTROM-OLSSON a H. KOVÁŘOVÁ. Cancer drug-resistance and a look at specific proteins: Rho GDP-dissociation inhibitor 2, Y-box binding protein 1, and HSP70/90 organizing protein in proteomics clinical application. Journal of Proteome Research. 2011, 10(2), 404-415, ISSN 1535-3893, IF: 5.113, PMID: 21067243
KREJCI, K., T. TICHÝ, P. HORAK, H. CIFERSKA, M. HAJDÚCH, J. SROVNAL, R. TROJANEC, M. ZEZULOVÁ, M. ZLEVOROVA, L. KALINOVA a J. ZADRAZIL. Merkel Cell Carcinoma of the Gluteal region with Ipsilateral Metastasi into the Pancreatic Graft of Patient after Combined Kidney-Pancreas Transplantation. Onkologie. 2010, 33(-), 520-524, ISSN 0378-584X, IF: 1.156, PMID: 20926899
JANČÍK, S., J. DRÁBEK, D. RADZIOCH a M. HAJDÚCH. Clinical Relevance of KRAS in Human Cancers. Journal of Biomedicine and Biotechnology. 2010, -(Article Number: 150960), 1-13, ISSN 1110-7243, IF: 1.230, PMID: 20617134
SOUCEK, K., P. GAJDUSKOVA, M. BRAZDOVA, M. HYZDALOVA, L. KOCI, D. VYDRA, R. TROJANEC, Z. PERNICOVA, L. LENTVORSKA, M. HAJDÚCH, J. HOFMANOVA a A. KOZUBIK. Fetal colon cell line FHC exhibits tumorigenic phenotype, complex karyotype, and TP53 gene mutation. Cancer Genetics and Cytogenetics. 2010, 197(2), 107-116, ISSN 0165-4608, IF: 1.551, PMID: 20193843
STROHALM, M., P. NOVAK, P. POMPACH, P. DŽUBÁK, P. MAN, D. KAVAN, M. WITT, M. HAJDÚCH a V. HAVLICEK. Utilization of high-accuracy FTICR-MS data in protein quantitation experiments. Journal of Mass Spectrometry. 2009, 44(11), 1565-70, ISSN 1076-5174, IF: 2.940, PMID: 19536796
HRADIL, P., J. HLAVÁČ, M. SOURAL, M. HAJDÚCH, M. KOLÁŘ a R. VEČEŘOVÁ. 3-Hydroxy-2-phenyl-4(1H)-quinolinones as Promising Biologically Active Compounds. Mini-reviews in Medicinal Chemistry. 2009, 9(6), 696-702, ISSN 1389-5575, IF: 3.132, PMID: 19519495
KOPŘIVA, F., P. DŽUBÁK, J. POTĚŠIL a M. HAJDÚCH. The anti-inflammatory effects of inhaled corticosteroids versus anti-leukotrienes on the lymphocyte P-glycoprotein (PGP) expression in asthmatic children. Journal of Astma. 2009, 46(4), 366-370, ISSN 0277-0903, IF: 1.330, PMID: 19484671
MARTINKOVA, J., S.J. GADHER, M. HAJDÚCH a H. KOVÁŘOVÁ. Challenges in cancer research and multifaceted approaches for cancer biomarker quest. FEBS Letters. 2009, 583(11), 1772-1784, ISSN 0014-5793, IF: 3.264, PMID: 19327356
PAPRSKÁŘOVÁ, M., V. KRYŠTOF, R. JORDA, P. DŽUBÁK, M. HAJDÚCH, J. WESIERSKA-GADEK a M. STRNAD. Functional p53 in cells contributes to the anticancer effect of the cyclin-dependent kinase inhibitor roscovitine. Journal of Cellular Biochemistry. 2009, 107(3), 428-437, ISSN 0730-2312, IF: 1.330, PMID: 19308936
GRINBERG-RASHI, H., E. OFEK, M. PERELMAN, J. ŠKARDA, P. YARON, M. HAJDÚCH, J. JACOB-HIRSCH, N. AMARIGLIO, M. KRUPSKY, D.A. SINAJSKY, Z. RAM, R. PFEFFER, I. GALERNTER, D.M. STEINBERG, I. BEN-DOV, G. RECHAVI a S. IZRAELI. The expression of three genes in primary non-small cell lung cancer is associated with metastatic spread to the brain. Clinical Cancer Research. 2009, 15(5), 1755-1761, ISSN 1078-0432, IF: 6.488, PMID: 19190132
GUILBAULT, C., G. WOJEWODKA, Z. SAEED, M. HAJDÚCH, E. MATOUK, J.B. DE SANCTIS a D. RADZIOCH. Cystic fibrosis fatty acid imbalance is linked to ceramide deficiency and corrected by fenretinide. American Journal of Respiratory Cell and Molecular Biology. 2009, 41(1), 100-106, ISSN 1044-1549, IF: 4.608, PMID: 19059886
HRABALEK, L., O. KALITA, H. ŠVÉBIŠOVÁ, J. EHRMANN, M. HAJDÚCH, R. TROJANEC a M. KALA. Dumbbell-shaped peripheral primitive neuroectodermal tumor of the spine-case report and review of the literature. Journal of Neuro-Oncology. 2009, 92(2), 211-217, ISSN 0167-594X, IF: 2.323, PMID: 19050994
SIRAK, I., J. PETERA, J. HATLOVA, M. VOSMIK, B. MELICHAR, J. DVORAK, Z. ZOUL, V. TYCOVA, M. LESKO a M. HAJDÚCH. Epidermal Growth Factor Receptor as a Predictor of Tumor Response to Preoperative Chemoradiation in Locally Advanced Gastric Carcinoma. Strahlentherapie und Onkologie. 2008, 184(11), 592-597, ISSN 0179-7158, IF: 3.357, PMID: 19016018
JANKU, F., J. SROVNAL, G. KOŘÍNKOVÁ, J. NOVOTNY, L. PETRUZELKA, D. POWER, B. MATOUS a M. HAJDÚCH. Molecular detection of disseminated breast cancer cells in the bone marrow of early breast cancer patients using quantitative RT PCR for CEA. Neoplasma. 2008, 55(4), 317-322, ISSN 0028-2685, IF: 1.208, PMID: 18505343
KALITA, O., M. KALA, H. ŠVÉBIŠOVÁ, J. EHRMANN, A. HLOBILKOVA, R. TROJANEC, M. HAJDÚCH a M. HOUDEK. Glioblastoma multiforme with an abscess: case report and literature review. Journal of Neuro-Oncology. 2008, 88(2), 221-225, ISSN 0167-594X, IF: 1.856, PMID: 18317688
ÜBERALL, I., Z. KOLÁŘ, R. TROJANEC, J. BERKOVCOVÁ a M. HAJDÚCH. The status and role of ErbB receptors in human cancer. Experimental and Molecular Pathology. 2008, 84(2), 79-89, ISSN 0014-4800, IF: 1.822, PMID: 18279851
VRZALIKOVA, K., J. ŠKARDA, J. EHRMANN, P. MURRAY, E. FRIDMAN, J. KOPOLOVIC, P. KNIZETOVA, M. HAJDÚCH, J. KLEIN, V. KOLEK, L. RADOVÁ a Z. KOLÁŘ. Prognostic value of Bmi-1 oncoprotein expression in NSCLC patiens: A tissue microarray study. Journal of Cancer Research and Clinical Oncology. 2008, 134(9), 1037-1042, ISSN 0171-5216, IF: 2.366, PMID: 18264721
SPÁČILOVÁ, L., P. DŽUBÁK, M. HAJDÚCH, S. KŘUPKOVÁ, P. HRADIL a J. HLAVÁČ. Synthesis and cytotoxic activity of various 5-[alkoxy-(4-nitro-phenyl]-methyl]-uracils in their racemic form. Biorganic & Medicinal Chemistry Letters. 2007, 17(23), 6647-6650, ISSN 0960-894X, IF: 2.538, PMID: 17935983
GUILBAULT, C., J.B. DE SANCTIS, G. WOJEWODKA, Z. SAEED, C. LACHANCE, T.A.A. SKINNER, R.M. VILELA, S. KUBOW, L.C. LANDS, M. HAJDÚCH a E. MATOUK. Fenretinide Corrects Newly Found Ceramide Deficiency in Cystic Fibrosis. American Journal of Respiratory Cell and Molecular Biology. 2008, 38(1), 47-56, ISSN 1044-1549, IF: 4.608, PMID: 17656682
TURASHVILI, G., J. BOUCHAL, K. BAUMFORTH, W. WEI, M. DZIECHCIARKOVA, J. EHRMANN, J. KLEIN, E. FRIDMAN, J. ŠKARDA, J. SROVNAL, M. HAJDÚCH, P. MURRAY a Z. KOLÁŘ. Novel markers for differentiation of lobular and ductal invasive breast carcinomas by laser microdissection and microarray analysis. BMC Cancer. 2007, 7(55), -, ISSN 1471-2407, IF: 2.359, PMID: 17389037
URBAN, M., J. ŠAREK, M. KVASNICA, I. TIŠLEROVÁ a M. HAJDÚCH. Triterpenoid Pyrazines and Benzopyrazines with Cytotoxic Activity. Journal of Natural products. 2007, 70(4), 526-532, ISSN 0163-3864, IF: 2.418, PMID: 17371067
KOPŘIVA, F., A. JANOŠŤÁKOVÁ, J. SZOTKOWSKA, M. ZAPALKA a M. HAJDÚCH. Montelukast decreases plasma endothelin-1 and serum eosinophil cationic protein levels in paediatric atopic asthma. Clinical Drug Investigation. 2006, 26(6), 351-356, ISSN 1173-2563, IF: 0.707, PMID: 17163269
KRAL, V., C. NEORAL, R. AUJESKY, R. HAVLÍK, J. KLEIN, M. HAJDÚCH, H. ŠVÉBIŠOVÁ, P. BENEŠ a R. VRBA. Neoadjuvant therapy for esophageal cancer-what can we accept?. Hepato-gastroenterology. 2006, 53(71), 720-722, ISSN 0172-6390, IF: 0.699, PMID: 17086876
KRYŠTOF, V., P. CANKAR, I. FRYŠOVÁ, J. SLOUKA, G. KONTOPIDIS, P. DŽUBÁK, M. HAJDÚCH, J. SROVNAL, W.F. DE AZAVEDO, M. ORSÁG, M. PAPRSKÁŘOVÁ, J. ROLČÍK, A. LÁTR, P.M. FISCHER a M. STRNAD. 4-Arylazo-3,5-diamino-1H-pyrazole CDK Inhibitors: SAR Study, Crystal Structure in Complex with CDK2, Selectivity, and Cellular Effects. Journal of Medicinal Chemistry. 2006, 49(22), 6500-6509, ISSN 0022-2623, IF: 4.926, PMID: 17064068
VEPŘEK, P., M. HAJDÚCH, P. DŽUBÁK, R. KUKLÍK, J. POLÁKOVÁ a K. BEZOUŠKA. Comblike Dendrimers Containing Tn Antigen Modulate Natural Killing and Induce the Production of Tn Specific Antibodies. Journal of Medicinal Chemistry. 2006, 49(21), 6400-6407, ISSN 0022-2623, IF: 4.926, PMID: 17034145
MENDOZA, L., M. HAJDÚCH, R. PLAUSINAITIS, V. PLATILOVA, N. EMRITTE a M. SVOBODA. Pharmacokinetic and bioequivalence testing of atorvastatin formulations in healthy male volunteers. Pharmazie. 2006, 61(9), 805-806, ISSN 0031-7144, IF: 0.677, PMID: 17020163
BOUCHALOVÁ, K., R. TROJANEC, Z. KOLÁŘ, K. CWIERTKA, I. ČERNÁKOVÁ, V. MIHÁL a M. HAJDÚCH. Analysis of ERBB2 and TOP2A gene status using fluorescence in situ hybridization versus immunohistochemistry in localized breast cancer. Neoplasma. 2006, 53(5), 393-401, ISSN 0028-2685, IF: 0.731, PMID: 17013533
JEGOROV, A., M. HAJDÚCH, M. ŠULC a V. HAVLÍČEK. Non-ribosomal cyclic peptides: Specific markers of fungal infections. Journal of Mass Spectrometry. 2006, 41(5), 563-576, ISSN 1076-5174, IF: 3.574, PMID: 16770826
SOURAL, M., J. HLAVÁČ, P. HRADIL, I. FRYŠOVÁ, M. HAJDÚCH, V. BERTOLASI a M. MALOŇ. Synthesis and Cytotoxic Activity of Substituted 2-Phenyl-3-Hydroxy-4(1H)-Quinolinones-7- Carboxylic Acids and their Phenacyl Esters. European Journal of Medicinal Chemistry. 2006, 41(4), 467-474, ISSN 0223-5234, IF: 2.022, PMID: 16540209
DŽUBÁK, P., M. HAJDÚCH, R. GAZAK, A. SVOBODOVÁ, J. PSOTOVÁ, D. WALTEROVÁ, P. SEDMERA a V. KREN. New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity. Bioorganic & Medicinal Chemistry. 2006, 14(11), 3793-3810, ISSN 0968-0896, IF: 2.286, PMID: 16466920
URBAN, M., J. ŠAREK, I. TIŠLEROVÁ, P. DŽUBÁK a M. HAJDÚCH. Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity. Bioorganic & Medicinal Chemistry. 2005, 13(19), 5527-5535, ISSN 0968-0896, IF: 2.018, PMID: 16087342
ŠAREK, J., M. KVASNICA, M. URBAN, J. KLINOT a M. HAJDÚCH. Correlation of cytotoxic activity of betulinines and their hydroxy analogues. Bioorganic & Medicinal Chemistry Letters. 2005, 15(19), 4196-4200, ISSN 0960-894X, IF: 2.333, PMID: 16051489
KVASNICA, M., J. ŠAREK, E. KLINOTOVÁ, P. DŽUBÁK a M. HAJDÚCH. Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity. Bioorganic & Medicinal Chemistry. 2005, 13(10), 3447-54, ISSN 0968-0896, IF: 2.018, PMID: 15848757
BIENOVA, M., R. KUCEROVA, M. FIURÁŠKOVÁ, M. HAJDÚCH a Z. KOLÁŘ. Androgenetic alopecia and current methods of treatment. Acta Dermatovenerologica. 2005, 14(1), 5-8, ISSN 0001-5555, IF: 1.558, PMID: 15818439
URBAN, M., J. ŠAREK, J. KLINOT, G. KOŘÍNKOVÁ a M. HAJDÚCH. Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity. Journal of Natural Products. 2004, 67(7), 1100-1105, ISSN 0163-3864, IF: 1.849, PMID: 15270560
ŠAREK, J., P. DŽUBÁK, E. KLINOTOVÁ, V. NOSKOVA, V. KŘEČEK, G. KOŘÍNKOVÁ, J.O. THOMSON, A. JANOŠŤÁKOVÁ, S. WANG, S. PARSONS, P.M. FISCHER, N. ZHELEV a M. HAJDÚCH. New lupane derived compounds with Pro-Apoptotic activity in cancer cells: Synthesis and structure-activity relationships. Journal of Medicinal Chemistry. 2003, 46(25), 5402-5415, ISSN 0022-2623, IF: 4.566, PMID: 14640549
JAROSOVA, M., M. HOLZEROVA, V. MIHÁL, I. LAKOMÁ, V. DIVOKÝ, B.. BLAZEK, D. POSPÍŠILOVÁ, M. HAJDÚCH, Z. NOVÁK, L. DUŠEK, J. KOPTÍKOVÁ, T. POULSEN a K. INDRAK. Complex karyotypes in childhood acute lymphoblastic leukemia: cytogenetic and molecular cytogenetic study of 21 cases. Cancer Genetics and Cytogenetics. 2003, 145(2), 161-168, ISSN 0165-4608, IF: 1.713, PMID: 12935929
NOSKOVA, V., P. DŽUBÁK, G. KUZMINA, A. LUDKOVÁ, D. STEHLÍK, R. TROJANEC, A. JANOŠŤÁKOVÁ, G. KOŘÍNKOVÁ, V. MIHÁL a M. HAJDÚCH. In vitro chemoresistance profile and expression/function of MDR associated proteins in resistant cell lines derived from CCRF-CEM, K562, A549 and MDA MB 231 parental cells. Neoplasma. 2002, 49(6), 418-425, ISSN 0028-2685, IF: 0.637, PMID: 12584592
DRÁBEK, J., M. HAJDÚCH, L. GOJOVÁ, E. WEIGL a V. MIHÁL. Frequency of 657del(5) mutation of the NBS1 gene in the Czech population by polymerase chain reaction with sequence specific primers. Cancer Genetics and Cytogenetics. 2002, 138(2), 157-159, ISSN 0165-4608, IF: 1.529, PMID: 12505263
SOVÁK, M., A.L. SELIGSON, M. KONAS, M. HAJDÚCH, M. DOLEZAL, R. MACHALA a R. NAGOURNEY. Herbal composition PC-SPES for management of prostate cancer: Identification of active principles. Journal of the National Cancer Institute. 2002, 94(17), 1275-1281, ISSN 0027-8874, IF: 14.240, PMID: 12208892
SOVÁK, M., A.L. SELIGSON, R. KUCEROVA, M. BIENOVA, M. HAJDÚCH a M. BUČEK. Fluridil, a rationally designed topical agent for androgenetic alopecia: first clinical experience. Dermatologic Surgery. 2002, 28(8), 678-685, ISSN 1076-0512, IF: 1.161, PMID: 12174057
MAĎAROVÁ, J., M. LUKEŠOVÁ, A. HLOBILKOVA, M. STRNAD, B. VOJTĚŠEK, R. LENOBEL, M. HAJDÚCH, P. MURRAY, S. PERERA a Z. KOLÁŘ. Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines. Journal of Clinical Pathology-Molecular Pathology. 2002, 55(4), 227-234, ISSN 1366-8714, IF: 2.549, PMID: 12147712
THOMSON, J.O., P. DŽUBÁK a M. HAJDÚCH. Prostate cancer and food supplement, PC-SPES. Minireview. Neoplazma. 2002, 49(2), 69-74, ISSN 0028-2685, IF: 0.637, PMID: 12088108
KOVÁŘOVÁ, H., M. HAJDÚCH, G. KOŘÍNKOVÁ, P. HALADA, S. KRUPIČKOVÁ, A. GOULDSWORTHY, N. ZHELEV a M. STRNAD. Proteomics approach in classifying the biochemical basis of the anticancer activity of the new olomoucine-derived synthetic cyclin-dependent kinase inhibitor, bohemine. Electrophoresis. 2000, 21(17), 3757-3764, ISSN 0173-0835, IF: 3.447, PMID: 11271495
ALBERIO, R., M. KUBELKA, V. ZAKHARTCHENKO, M. HAJDÚCH, E. WOLF a J. MOTLIK. Activation of Bovine Oocytes by Specific Inhibition of Cyclin-Dependent Kinases. Molecular Reproduction and Development. 2000, 55(4), 422-432, ISSN 1040-452X, IF: 2.658, PMID: 10694750
KOVÁŘOVÁ, H., L. HERNYCHOVA, M. HAJDÚCH, M. SIROVA a A. MACELA. Influence of the Bcg Locus on Natural Resistance to Primary Infection with Facultative Intracellular Bacterium Francisella tularensis in Mice. Infection and Immunity. 2000, 68(3), 1480-1484, ISSN 0019-9567, IF: 4.184, PMID: 10678963
JAWOREK, H., B. ZBORILOVA, V. KOUDELÁKOVÁ, J. BREZINOVA, J. VRBKOVÁ, I. OBORNA a M. HAJDÚCH. Prevalence of Human Papillomavirus Infection in Oocyte Donors and Women Treated for Infertility: An Observational Laboratory-Based Study. European Journal of Obstetrics & Gynecology and Reproductive Biology: X. 2019, 4, 100068, ISSN 2590-1613, IF: 2.024, PMID: 1517300
KADRIĆ, J., K. MOTYKA, P. DŽUBÁK, M. HAJDÚCH a M. SOURAL. Synthesis, cytotoxic activity, and fluorescence properties of a set of novel 3-hydroxyquinolin-4(1H)-ones. Tetrahedron Letters. 2014, 55(26), 3592-3595, ISSN 0040-4039, IF: 2.379,
POTĚŠIL, J., F. KOPŘIVA, P. DŽUBÁK, M. GODOVA, L. RADOVÁ, J. SROVNAL, V. MIHÁL a M. HAJDÚCH. Expression of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in peripheral blood lymphocytes amongst children and young adults. Central European Journal of Immunology. 2013, 38(4), 518-529, ISSN 1426-3912, IF: 0.358,
PERLÍKOVÁ, P., P. KONEČNÝ, P. NAUŠ, J. SNÁŠEL, I. VOTRUBA, P. DŽUBÁK, I. PICHOVÁ, M. HAJDÚCH a M. HOCEK. 6-Alkyl-, 6-aryl- or 6-hetaryl-7-deazapurine ribonucleosides as inhibitors of human or MTB adenosine kinase and potential antimycobacterial agents. Medicinal Chemistry Communications. 2013, 4(11), 1497-1500, ISSN 2040-2503, IF: 2.626,
CALETKOVÁ, O., A. LÁSIKOVÁ, M. HAJDÚCH, P. DŽUBÁK a T. GRACZA. Synthesis and antitumour activity of varitriol and its analogues. Archive for Organic Chemistry. 2012, 2012(6), 365-383, ISSN 1551-7004, IF: 1.057,
GUCKÝ, T., E. ŘEZNÍČKOVÁ, P. DŽUBÁK, M. HAJDÚCH a V. KRYŠTOF. Synthesis and anticancer activity of some 1,5-diaryl-3-(3,4,5-trihydroxyphenyl)-1H-pyrazolo[4,3-e][1,2,4]triazines. Monatshefte fur Chemie. 2010, 141(6), 709-714, ISSN 0026-9247, IF: 1.356,
NEDVĚD, J., M. HAJDÚCH, K. LEMR a V. HAVLÍČEK. Hmotnostní spektrometrie v nádorové diagnostice. Chemické Listy. 2011, 105(5), 356-360, ISSN 0009-2770, IF: 0.529,
DRÁBEK, J. Two Fagan nomograms for the (genetic) evidence in a judicial context. Australian Journal of Forensic Sciences. 2014, 46(3), 266-271, ISSN 0045-0618, IF: 0.583,
KALIVODOVÁ, A., K. HRON, P. FILZMOSER, L. NAJDEKR, H. JANEČKOVÁ a T. ADAM. PLS-DA for Compositional Data with Application to Metabolomics. Journal of Chemometrics. 2015, 29(1), 21-28, ISSN 0886-9383, IF: 1.873,
JANSA, J., A. LYČKA, Z. PADELKOVA, M. GREPL, P. KONEČNÝ, M. HAJDÚCH a P. DŽUBÁK. New Imidazo[1,2-c]pyrimidin-5(6H)-Ones Derived from Cytosine: Synthesis, Structure, and Cytotoxic Activity. Journal of Heterocyclic Chemistry. 2015, 52, 1382-1389, ISSN 0022-152X, IF: 0.685,
FUNK, P., K. MOTYKA, P. DŽUBÁK, P. ZNOJEK, S. GURSKÁ, J. KUSZ, C. MCMASTER, M. HAJDÚCH a M. SOURAL. Preparation of 2-phenyl-3-hydroxyquinoline- 4(1H)-one-5-carboxamides as potential anticancer and fluorescence agents. RSC Advances. 2015, 5(60), 48861-48867, ISSN 2046-2069, IF: 3.289,
KLECKA, M., L. SLAVĚTÍNSKÁ, E. TLOUŠŤOVÁ, P. DŽUBÁK, M. HAJDÚCH a M. HOCEK. Synthesis and cytostatic activity of 7-arylsulfanyl-7-deazapurine bases and ribonucleosides. MedChemComm. 2015, 6(4), 576-580, ISSN 2040-2503, IF: 2.319,
DŽUBÁK, P., M. HAJDÚCH, D. VYDRA, A. HÚŠŤOVÁ, M. KVASNICA, D. BIEDERMANN, L. MARKOVÁ, M. URBAN a J. ŠAREK. Pharmacological activities of natural triterpenoids and their therapeutic implications. Natural Product Reports. 2006, 23(3), 394-411, ISSN 0265-0568, IF: 7.325,
JEGOROV, A., M. HAJDÚCH, M. ŠULC a V. HAVLÍČEK. Non-ribosomal cyclic peptides: Specific markers of fungal infections. Journal of Mass Spectrometry. 2006, 41, 563-576, ISSN 1076-5174, IF: 3.574,
VEPŘEK, P., M. HAJDÚCH, P. DŽUBÁK, R. KUKLÍK, J. POLÁKOVÁ a K. BEZOUŠKA. Comblike Dendrimers Containing Tn Antigen Modulate Natural Killing and Induce the Production of Tn Specific Antibodies. Journal of Medicinal Chemistry. 2006, 49(21), 6400-6407, ISSN 0022-2623, IF: 4.926,
MAYER, M., K. URBANEK a M. HAJDÚCH. Luminol-dependent chemiluminiscence of monocyte and granulocyte chemiluminiscence determination in multiple sclerosis: The effect of autologous thrombocytes. Folia Biologica. 1991, 37(3-4), 213-223, ISSN 0015-5500, IF: 0.632,
MIHÁL, V., J. DUSEK, M. HAJDÚCH, J. COHEN, H. FINGEROVA a J. VESELY. Transient aplastic crisis in a leukaemia child, caused by the parvovirus B19 infection. Pediatric Hematology and Oncology. 1996, 13(2), 173-176, ISSN 0888-0018, IF: 0.540,
HAJDÚCH, M., V. MIHÁL, J. MINARIK, E. FABER, M. SAFAROVA, E. WEIGL a P. ANTALEK. Decrease in vitro chemosensitivity of tumour cells in patients suffering from malignant diseases with a poor prognosis. Cytotechnology. 1996, 19(3), 243-245, ISSN 0920-9069, IF: 0.540,
MERKUNOVA, A., M. HAJDÚCH, R. NEMCEK, L. VIDEMANOVA a E. WEIGL. Bacterial Immunomodulator Olimunostim Inhibits Degranulation of Mastocytes In Vitro. Folia Biologica. 1996, 42(5), 237-241, ISSN 0015-5500, IF: 0.632,
MIHÁL, V., M. HAJDÚCH, J. DUSEK, E. WEIGL, M. JAROSOVA, Z. PIKALOVA a M. SAFAROVA. Differential chemosensitivity of leukemic cells in myeloid and lymphoid phase of stem cell leukaemia (a case report). Neoplasma. 1997, 44(2), 133-136, ISSN 0028-2685, IF: 0.657,
HAJDÚCH, M., Z. KOLÁŘ, R. NOVOTNY, J. HANUS, V. MIHÁL, A. HLOBILKOVA, V. NOSKOVA a M. STRNAD. Induction of apoptosis and regression of spontaneous dog melanoma following in vivo application of synthetic cyclin dependent kinase inhibitor olomoucine. Anti-Cancer Drugs. 1997, 8(10), 1007-1013, ISSN 0959-4973, IF: 1.320,
KOVAROVA, H., M. HAJDÚCH, D. RADZIOCH a A. MACELA. Natural resistance to infection with intracellular pathogens: cross-talk between Nramp1 and Lps genes. Electrophoresis. 1997, 18(14), 2654-2660, ISSN 0173-0835, IF: 3.054,
SOURAL, M., J. HLAVÁČ, P. HRADIL a M. HAJDÚCH. Efficient Synthesis and Cytotoxic Activity of Some Symmetrical Disulfides Derived from the Quinolin-4(1H)-one Skeleton. European Journal of Organic Chemistry. 2009, -(23), 3867-3870, ISSN 1434-193X, IF: 3.016,
KOVAROVA, H., D. RADZIOCH, M. HAJDÚCH, M. SIROVA, V. BLAHA, A. MACELA, J. STULIK a L. HERNYCHOVA. Natural resistance to intracellular parasites: A study by two-dimmensional gel electrophoresis coupled with multivariate analysis. Electrophoresis. 1998, 19(8-9), 1325-1331, ISSN 0173-0835, IF: 3.054,
HAJDÚCH, M., R. NEMCEK, P. VITEK, A. MACELA, L. VIDEMANOVA a H. KOVAROVA. Infection activated T-lymphocytes resist nitric oxide mediated immunosuppression in the course of Francisella tularensis 15L experimental infection. Folia Biologica. 1998, 44(6), 193-200, ISSN 0015-5500, IF: 0.632,
HAJDÚCH, M., J. DRÁBEK, V. RACLAVSKÝ, V. KOTALA a T. MICHALEK. Diversity among wild type and vaccination strains of Trichophyton verrucosum investigated by random amplified polymorphic DNA analysis. Folia Biologica. 1999, 45(4), 151-155, ISSN 0015-5500, IF: 0.632,
ŠULC, M., K. PESLOVA, M. ZABKA, M. HAJDÚCH a V. HAVLICEK. Biomarkers of Aspergillus spores: Strain typing and protein identification. International Journal of Mass Spectrometry. 2009, 280(-), 162-168, ISSN 1387-3806, IF: 2.411,
GUCKÝ, T., I. FRYŠOVÁ, J. SLOUKA, M. HAJDÚCH a P. DŽUBÁK. Cyclocondensation reaction of heterocyclic carbonyl compounds, Part XIII: Synthesis and cytotoxic activity of some 3,7-diaryl-5-(3,4,5-trimethoxyphenyl)pyrazolo[4,3-e][1,2,4]triazines. European Journal of Medicinal Chemistry. 2009, 44(2), 891-900, ISSN 0223-5234, IF: 2.882,
STÝSKALA, J., L. STÝSKALOVÁ, J. SLOUKA a M. HAJDÚCH. Synthesis of 2-aryl-4-(benzimidazol-2-yl)-1,2-dihydro[1,2,4]triazino-[4,5-a]benzimidazol-1-one derivatives with preferential cytotoxicity against carcinoma cell lines. European Journal of Medicinal Chemistry. 2008, 84(2), 449-455, ISSN 0223-5234, IF: 2.301,
URBAN, M., J. KLINOT, I. TIŠLEROVÁ, D. BIEDERMANN, M. HAJDÚCH a I. CISAROVA. Reactions of activated lupane oxo-compounds with diazomethane: An approach to new derivatives of cytotoxic triterpenes. Synthesis-Stuttgart. 2006, 23(-), 3979-3986, ISSN 0039-7881, IF: 2.401,
BIEDERMANN, D., J. ŠAREK, J. KLINOT, M. HAJDÚCH a P. DŽUBÁK. Fluorination of betulinines and other triterpenoids with DAST. Synthesis-Stuttgart. 2005, -(7), 1157-1163, ISSN 0039-7881, IF: 2.203,
MIHÁL, V., M. HAJDÚCH, V. NOSKOVA, A. JANOŠŤÁKOVÁ, M. SAFAROVA, M. OREL, G. KUZMINA, B.. BLAZEK a D. POSPÍŠILOVÁ. The analysis od correlations between drug resistance and clinical/laboratory measures found in a group of children with all treated by ALL-BFM 90 protocol. Bulletin du Cancer. 2004, 91(4), -, ISSN 0007-4551, IF: 0.654,
SELIGSON, A.L., J.W. CAMPION, R.C. TERRY, R. KUCEROVA, M. BIENOVA, M. HAJDÚCH a M. SOVÁK. Development of Fluridil, a topical suppressor of the androgen receptor in androgentic alopecia. Drug Development Research. 2003, 59(3), 292-306, ISSN 0272-4391, IF: 1.325,
TRAVNICEK, Z., M. MALOŇ, M. BILER, M. HAJDÚCH, P. BROŽ, K. DOLEZAL, J. HOLUB, V. KRYŠTOF a M. STRNAD. Synthesis, characterization and biological activity of two nickel(II) complexes with 6-(2-chlorobenzylamino)purine. Transition Metal Chemistry. 2000, 25(3), 265-269, ISSN 0340-4285, IF: 0.825,
WALACH, J., P. FILZMOSER, K. HRON, B. WALCZAK a L. NAJDEKR. Robust biomarker identification in a two-class problem based on pairwise log-ratios. Chemometrics and Intelligent Laboratory Systems. 2018, 171(2017), 277-285, ISSN 0169-7439, IF: 2.303,
CHALOUPKOVA, Z., A. BALZEROVA, Z. MEDRIKOVA, J. SROVNAL, M. HAJDÚCH, K. CEPE, V. RANC a R. ZBOŘIL. Label-free determination and multiplex analysis of DNA and RNA in tumor tissues. Applied Materials Today. 2018, 12(2018), 85-91, ISSN 2352-9407, IF: 1.691,
MARTINEZ, G., M. MIJARES a J.B. DE SANCTIS. nema IF_Effects of Flavonoids and Its Derivatives on Immune Cell Responses. Recent Patents on Inflammation & Allergy Drug Discovery 2019. 2019, 13(2), 1-21, ISSN x, IF: x,
CHARRIS, J., M. MONASTERIOS, M. ACOSTA, M. RODRIGUEZ, N. GAMBOA, G. MARTINEZ, H. ROJAS, M. MIJARES a J.B. DE SANCTIS. Antimalarial, antiproliferative, and apoptotic activity of quinoline-chalcone and quinoline-pyrazoline hybrids. A dual action. Medical Chemistry Research. 2019, 28(11), 2050-2066, ISSN 1054-2523, IF: 1.720,
RAMIREZ, H., J. RODRIGUES, M. MIJARES, J.B. DE SANCTIS a J. CHARRIS. Synthesis and biological activity of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivatives as antimalarial and cytotoxic agents. Journal of Chemical Research. 2020, 44(5-6), 305-314, ISSN 1747-5198, IF: 0.593,
GABLO, N., K. TRACHTOVA, V. PROCHAZKA, J. HLAVSA, T. GROLICH, I. KISS, J. SROVNAL, A. ŘEHULKOVÁ, M. LOVEČEK, P. SKALICKÝ, I. BERINDAN-NEAGOE, Z. KALA a O. SLABÝ. Identification and Validation of Circulating Micrornas as Prognostic Biomarkers in Pancreatic Ductal Adenocarcinoma Patients Undergoing Surgical Resection. Journal of Clinical Medicine. 2020, 9, 2440, ISSN 2077-0383, IF: 3.303,
RIMPELOVA, S., T. ZIMMERMANN, P. DRAŠAR, B.. DOLENSKY, J. BEJCEK, E. KMONICKOVA, P. CIHLAROVA, S. GURSKÁ, L. KUKLIKOVA, M. HAJDÚCH, T. RUML, L. OPLETAL, P. DŽUBÁK a M. JURÁŠEK. Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity. Foods. 2021, 10(1), 136, ISSN 2304-8158, IF: 4.092,
VÁCLAVKOVÁ, J., P. KOUŘILOVÁ, J. VRBKOVÁ, D. HOLUB, M. HAJDÚCH a P. DŽUBÁK. Proteomic Analysis of Exhaled Breath Condensate Samples: High Reproducibility of Mass Spectrometric Measurements. Chemické listy. 2020, 114(7), 470-479, ISSN 1213-7103, IF: 0.39,
VÁCLAVKOVÁ, J., T. OŽDIAN, M. HAJDÚCH a P. DŽUBÁK. Body Fluids as a Source of Proteomic Biomarkers of Various Diseases. Chemické listy. 2020, 114(3), 209-2015, ISSN 0009-2770, IF: 0.39,
PORUBSKÝ, M., S. GURSKÁ, J. STANKOVÁ, M. HAJDÚCH, P. DŽUBÁK a J. HLAVÁČ. Amino-BODIPY as the ratiometric fluorescent sensor for monitoring drug release or "power supply" selector for molecular electronics. RSC Advances. 2019, 9(43), 25075-25083, ISSN 2046-2069, IF: 3.119,
VELTMAN, M., J.B. DE SANCTIS, M. STOLARCZYK, N. KLYMIUK, A. BÄHR, R. BROUWER, E. OOLE, J. SHAH, T. OŽDIAN, J. LIAO, C. MARTI, D. RADZIOCH, J. HANRAHAN a B. SCHOLTE. CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells. Frontiers in Physiology. 2021, 2021 (12), 619442, ISSN 1664-042X, IF: 3.367,
DOSTAL, Z., M. SEBERA, J. SROVNAL, K. ŠTAFFOVÁ a M. MODRIANSKÝ. Dual Effect of Taxifolin on ZEB2 Cancer Signaling in HepG2 Cells. Molecules. 2021, 2021(26), 1476, ISSN 1420-3049, IF: 3.267,
SROVNAL, J., Z. CAPKOVA, P. CAPKOVA, M. PROCHAZKA a M. HAJDÚCH. Duplication of 9p24.3 in three unrelated patients with autistic spectrum disorder. Molecular Genetics and Metabolism. 2021, 132, 136-136, ISSN 1096-7192, IF: 4.797,
MUDSANI, G., K. PAIDIKONDALA, R. GUNDLA, S. MADDIRALA a V. DAS. Synthesis and Biological Evaluation of 5 '-Arylspiro[piperidine-4,3 '-pyrrolo-[2,3-b]pyridin] Analogues. Chemistryselect. 2021, 6(14), 3378-3381, ISSN 2365-6549, IF: 2.109,
MUDASANI, G., K. PAIDIKONDALA, S. GURSKÁ, S. MADDIRALA, P. DŽUBÁK, V. DAS a R. GUNDLA. C-5 Aryl Substituted Azaspirooxindolinones Derivatives: Synthesis and Biological Evaluation as Potential Inhibitors of Tec Family Kinases. European Journal of Organic Chemistry. 2022, 2021(33), 4630-4640, ISSN 1434-193X, IF: 3.021,
DUMUT, D., J.B. DE SANCTIS, M. MISTRÍK, Z. ŠKROTT, P. DŽUBÁK, J. BÁRTEK, M. HAJDÚCH a D. RADZIOCH. ?chybi pdf_Meeting abstract_Dithiocarb-copper complex, CuET, demonstrates anti-neoplastic activity in mouse model of prostate cancer and prevents recurrence of tumors. Cance Research. 2021, 81(13), 1251, ISSN 0008-5472, IF: 12.701,
SAINI, H., P. KALLEM, E. OTYEPKOVA, F. GEYER, A. SCHNEEMANN, V. RANC, F. BANAT, R. ZBOŘIL, M. OTYEPKA, R. FISCHER a K. JAYARAMULU. Two-dimensional MOF-based liquid marbles: surface energy calculations and efficient oil-water separation using a ZIF-9-III@PVDF membrane. Journal of Material chemistry A. 2021, 9(41), 23651-23659, ISSN 2050-7488, IF: 12.732,
PATRYKEI, S., Y. KOROBKO, O. OGORODNIICHUK, M. GAZARD, P. POLISHCHUK, P. DŽUBÁK, S. GURSKÁ, M. HAJDÚCH a R. LESYK. Synthesis and evaluation of the anticancer activity of some semisynthetic derivatives of rutaecarpine and evodiamine. Synthetic communications. 2021, 51(21), 3237-3245, ISSN 0039-7911, IF: 2.007,
CENTORAME, A., D. DUMUT, M. YOUSSEF, M. ONDRA, I. KIANICKA, J. SHAH, R. PAUN, T. OŽDIAN, J. HANRAHAN, E. GUSEV, B.J. PETROF, M. HAJDÚCH, R. PISLARIU, J.B. DE SANCTIS a D. RADZIOCH. Treatment With LAU-7b Complements CFTR Modulator Therapy by Improving Lung Physiology and Normalizing Lipid Imbalance Associated With CF Lung Disease. Frontiers inPharmacology. 2022, 13, 876842, ISSN 1664-3224, IF: 5.810,
KVAKOVA, K., M. ONDRA, J. SCHIMER, M. PETŘÍK, Z. NOVÝ, H. RAABOVA, M. HAJDÚCH a P. CIGLER. Visualization of Sentinel Lymph Nodes with Mannosylated Fluorescent Nanodiamonds. Advanced Functional Materials. 2022, 32(23), 2109960, ISSN 1616-301X, IF: 18.808,
GARMENDIA, J., A. GARCIA, C.V. DE SANTCTIS, M. HAJDÚCH a J.B. DE SANCTIS. Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19. Current Issues in Molecular Biology. 2022, 45, 33-50, ISSN 1467-3037, IF: 2.976,

Other Reviewed Journals

DE SANCTIS, J.B., J. GARMENDIA a M. HAJDÚCH. Overview of Memory NK Cells in Viral Infections: Possible Role in SARS-CoV-2 Infection. Immuno. 2022, 2022(2), 52-67. ISSN 2673-5601.
GERYK, M., E. KARASKOVA, M. VELGANOVA-VEGHOVA, B. LUDÍKOVÁ, J. CIVRNY a J. VOLEJNÍKOVÁ. Objemný gastroduodenální trichobezoár (Rapunzel syndrom) jako příčina bolestí břicha a nechutenství u devítileté dívky. Česko-slovenská pediatrie 2021. 2021, 76(4), 233-237. ISSN 0069-2328.
GARMENDIA, J. a J.B. DE SANCTIS. A Brief Analysis of Tissue-Resident NK Cells in Pregnancy and Endometrial Diseases: The Importance of Pharmacologic Modulation. Immuno. 2021, 2021(1), 174-193. ISSN 2673-5601.
LUKÁŠ, J., J. DRÁBEK, D. LUKAS, I. ZEMANOVA a A. RULSEH. Ectopic thyroid with benign and malignant findings: A case series. International Journal of Surgery Case Reports. 2020, 66, 33-38. ISSN 2210-2612. PMID: 31 790 949
ŠPORIKOVÁ , Z., V. KOUDELÁKOVÁ a M. HAJDÚCH. Prognostic and predictive factorrs in breast cancer patients. Onkologocká revue. 2019, 2019(1), 52-57. ISSN 2464-7195.
PRASIL, P., T. GABRHELIK, J. SROVNAL, L. VECERA a E. BERTA. Vliv opioidů na diseminaci nádorové choroby po chirurgickém výkonu. Bolest. 2019, 21(2), 52-57. ISSN 1212-0634.
DVOŘAN, M., J. VODICKA, J. DOSTÁL, M. HAJDÚCH, P. DŽUBÁK, M. PESKOVA a R. PILKA. Implantation and diagnostics of endometrial receptivity. Česká gynekologie. 2019, 83(4), 291-298. ISSN 1210-7832. PMID: 30 441 961
BÉBAROVÁ, L., P. SKALICKÝ, J. SROVNAL, A. PROKOPOVÁ, J. ZAPLETALOVÁ, M. HAJDÚCH a M. LOVECEK. The effect of circulating tumor cells on the survival of patients with pancreatic cancer − 5-year results. Rozhledy v chirurgii. 2018, 97(2), 94-98. ISSN 0035-9351.
PRASIL, P., T. GABRHELIK, J. SROVNAL, L. VECERA a E. BERTA. Opioidy a perioperační ovlivnění imunitního systému. Bolest. 2018, 21(11), 21-26. ISSN 1212-0634.
DRÁBEK, J. (Ne)reprodukovatelnost výsledků v biomedicíně. Postgraduální medicína. 2018, 20(2), 227-230. ISSN 1212-4184.
KULTAN, J., V. KOLEK, P. DŽUBÁK, J. VÁCLAVKOVÁ, M. HAJDÚCH a M. SZKORUPA. Možnosti neinvazivní detekce karcinomu plic. Studia Pneumologica et Phthiseologica. 2018, 78(3), 69-75. ISSN 1213-810X.
DRÁBEK, J. neni recenzovaný_Hloubkova geneticka analyza 15 klonu Chardonnay. Vinařský obzor. 2018, 12(111), 602-603. ISSN x.
KLOS, D., M. STASEK, M. LOVECEK, P. SKALICKÝ, R. VRBA, R. AUJESKY, R. HAVLÍK, C. NEORAL, L. VARANASI, M. HAJDÚCH, J. VRBKOVÁ a P. DŽUBÁK. Tumor cells transfer between the patient and laboratory animal as a basic methodological approach to the study of cancerogenesis and identification of biomarkers. Rozhledy v Chirurgii. 2018, 95(12), 432-438. ISSN 0035-9351. PMID: 28 182 438
CAPKOVA, L., M. KALINOVA, L. TICHA, E. PAROBKOVA, M. MATEJCKOVA, H. VOSMIKOVA, O. HORKY, K. BARTÁKOVÁ, J. DRÁBEK, M. BAJEROVA a P. DUNDR. Detekce EGFR mutaci v cirkulujici nadorove DNA (ctDNA) v plazme - mezilaboratorni porovnavani referencnich laboratori v Ceske republice. Klinicka onkologie. 2018, 5, 353-360. ISSN 1803-6597.
SUMMER, D., S. MAYR, M. PETŘÍK, C. RANGGER, K. SCHOELER, B. MATUSZCZAK a C. DECRISTOFORO. Pretargeted Imaging with Gallium-68-Improving the Binding Capability by Increasing the Number of Tetrazine Motifs. Pharmaceuticals (Basel, Switzerland). 2018, 11(4), pii: E102. ISSN 1424-8247.
RYSKA, A., O. HORKY, J. BERKOVCOVÁ, I. TICHA, M. KALINOVA, M. MATEJCKOVA, A. BODAY, J. DRÁBEK, P. MARTINEK, J. SIMOVA, K. SIEGLOVA a H. VOSMIKOVA. afiliace FN_Malignant Melanoma - from Classical Histology towards Moleculat Genetic Testing. Klinická onkologie. 2017, 30(3), 182-189. ISSN 0862-495X.
HOUDOVÁ MEGOVÁ , M., J. DRÁBEK, Z. DWIGHT, R. TROJANEC, V. KOUDELÁKOVÁ, J. VRBKOVÁ, O. KALITA, S. MLČOCHOVÁ, M. RABČANOVÁ a M. HAJDÚCH. Isocitrate Dehydrogenase Mutations are Better Prognostic Marker than O6-methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastomas - a Retrospective, Single-centre Molecular Genetics Study of Gliomas. Klinická onkologie. 2017, 30(5), 361-371. ISSN 0862-495X.
DRÁBEK, J. Omyly při soudním procesu. Bulletin advokacie. 2017, x(x), x. ISSN 1875-1768.
KADLČÍKOVÁ, D., K. FUSEK a J. DRÁBEK. High resolution melting of Short Tandem Repeats amplicons. Forensic Science International: Genetics Supplement Series. 2017, 6, e335-e336. ISSN 1875-1768.
KUFOVA, Z., T. SEVCIKOVA, K. GROWKOVA, P. VOJTA, J. FILIPOVA, Z. ADAM, L. POUR, M. PENKA, R. RYSAVA, P. NEMEC, L. BROZOVA, P. VYCHYTILOVA, A. JURCZYSZYN, S. GROSICKI, A. BARCHNICKA, M. HAJDÚCH, M. SIMICEK a R. HAJEK. Biomarkers in Immunoglobulin Light Chain Amyloidosis. Klinická Onkologie. 2017, 30(2), 75-80. ISSN 0862-495X. PMID: 28 903 574
ZATOPKOVA, M., J. FILIPOVA, T. JELINEK, P. VOJTA, T. SEVCIKOVA, M. SIMICEK, L. RIHOVA, R. BEZDEKOVA, K. GROWKOVA, Z. KUFOVA, J. SMEJKALOVA, M. HAJDÚCH, L. POUR, J. MINARIK, A. JUNGOVA, V. MAISNAR, F. KRYUKOV a R. HAJEK. Whole Exome Sequencing of Aberrant Plasma Cells in a Patient with Multiple Myeloma Minimal Residual Disease. Klinická Onkologie. 2017, 30(2), 75-80. ISSN 0862-495X. PMID: 28 903 574
HOLUB, D., J. HOUDA, M. HAJDÚCH, D. POSPÍŠILOVÁ a P. DŽUBÁK. Stanovení hladiny hepcidinu-25 v séru pomocí SPE_LC_MS/MS metody. Chemagazín. 2016, 5, 8-10. ISSN 1210-7409.
OŽDIAN, T., D. HOLUB, G. RYLOVÁ, J. VÁCLAVKOVÁ, M. HAJDÚCH a P. DŽUBÁK. Porovnání hmotnostně spektrometrických přístupů v proteomickém profilování léčiv. Chemagazín. 2016, 5, 8-11. ISSN 1210-7409.
PETŘÍK, M., C. ZHAI, H. HAAS a C. DECRISTOFORO. Siderophores for molecular imaging applications. Clinical and Translational Imaging. 2016, 5(1), 15-27. ISSN 2281-5872 . PMID: 28 138 436
REHULKA, P., R. KUBA, M. HERMANOVA, A. CHASOVSKYKH a M. BRAZDIL. Sporadická forma meningioangiomatózy. Neurologie pro praxi. 2016, 17(2), 104-107. ISSN 1213-1814.
MOKSHYNA, E., P. POLISHCHUK, V. NEDOSTUP a V. KUZMIN. QSPR-Modeling for the Second Virial Cross-Coefficients of Binary Organic Mixtures. International Journal of Quantitative Structure-Property Relationships. 2016, 2016(1), 72-84. ISSN 2379-7487.
KOLECKOVA, M., G. KOŘÍNKOVÁ, V. KOUDELÁKOVÁ, J. POTOČKOVÁ, B. ŠOPÍKOVÁ, M. HAJDÚCH a Z. KOLÁŘ. Metoda RNAscope pro analýzu exprese HER2 ve vzorcích karcinomů mléčné žlázy s neprokázanou amplifikací. Onkologie. 2015, 9(5), 245-247. ISSN 1802-4475 .
DRÁBEK, J. 40 Inventive Principles for Genetic Diagnostic Laboratories. The Triz Journal. 2015, x, x. ISSN x.
KULTAN, J., V. KOLEK, L. FAJKOSOVA, M. HAJDÚCH, J. DRÁBEK, T. TICHÝ a R. TACHEZY. Recurrent respiratory papillomatosis successfully treated with gefitinib: a case study. American Journal of Medical Case Reports. 2015, 3(11), 352-358. ISSN 2374-2151.
DRÁBEK, J. Activity level in the hierarchy of propositions in case of the People of the State of California v. Orenthal James Simpson analyzed using Bayesian network. Forensic Science International: Genetics Supplement Series. 2015, 5(-), e67-e68. ISSN 1875-1768 .
ONDRYÁŠOVÁ, H., V. KOUDELÁKOVÁ, J. DRÁBEK, P. VANEK, R. SLAVKOVSKÝ a M. HAJDÚCH. Utilization of self-sampling kits for HPV testing in cervical cancer screening - pilot study. Česká gynekologie. 2015, 80(6), 436-443. ISSN 1210-7832.
KONEČNÝ, P., S. GURSKÁ, P. ZNOJEK, E. SCHADICH, M. HAJDÚCH a P. DŽUBÁK. Reprofilování jako úspěšná strategie hledání nových léčiv. Farmakologická léčba. 2015, 4(10/2015), 12-18. ISSN 1805-398X.
GHOTHIM, M., J. SROVNAL, L. BÉBAROVÁ, J. TESAŘÍKOVÁ, P. SKALICKÝ, D. KLOS, A. PROKOPOVÁ, M. VAHALÍKOVÁ, H. SLAVÍK, J. VRBKOVÁ, C. NEORAL, R. HAVLÍK, M. HAJDÚCH a M. LOVEČEK. Determination of CEA, EGFR and hTERT expression in peritoneal lavage in patients with pancreatic adenocarcinoma using RT - PCR method. Rozhledy v chirurgii. 2015, 94(11), 464-9. ISSN 0035-9351 . PMID: 26 766 154
SPENEROVA, M., J. SROVNAL, J. POTĚŠIL, M. HAJDÚCH, V. MIHÁL a P. DŽUBÁK. Historie glukokortikoidní terapie v léčbě akutních leukémií u dětí. Česko-slovenská pediatrie. 2014, 69(6), 350-362. ISSN 0069-2328.
KOVARIKOVA, A., R. HEZOVA, J. SROVNAL, M. REDOVA a O. SLABÝ. Role mikroRNA v molekulární patologii karinomu jícnu a jejich potenciální využití v klinické onkologii. Klinická onkologie. 2014, 27(2), 87-86. ISSN 0862-495X.
DRÁBEK, J. Odmitnuti zaveru znaleckeho posudku v anglickem pripadu R proti T. Trestněprávní revue. 2014, 2(13), 40-43. ISSN 1213-5313.
HOUDA, J., P. DŽUBÁK, E. KARASKOVA, D. HOLUB, D. VYDRA, D. MLCUCHOVA, M. HAJDÚCH, O. POZLER a D. POSPÍŠILOVÁ. Výskyt anemie a význam měření hladiny hepcidinu metodou ELISA u dětí s nespecifickými střevními záněty. Česko-slovenská pediatrie. 2014, 69(3), 137-147. ISSN 0069-2328.
ONDRYÁŠOVÁ, H., V. KOUDELÁKOVÁ a M. HAJDÚCH. Karcinom cervixu-možnosti detekce lidského papilomaviru. Česká gynekologie. 2013, 78(3), 289-294. ISSN 1210-7832.
POSPÍŠILOVÁ, D., J. HOUDA, D. HOLUB, B. LUDÍKOVÁ, R. MOJZIKOVA, P. POSPISILOVA, Z. ŽIDOVÁ, K. KAPRALOVA, M. HORVÁTHOVÁ, M. HAJDÚCH a P. DŽUBÁK. Význam stanovení hladiny hepcidinu v diagnostice vybraných typů anémií v dětském věku. Transfuze a hematologie dnes. 2012, 18(-), 58-65. ISSN 1213-5763.
NEUWIRTHOVA, J., P. SMILEK, J. JARKOVSKÝ, L. DUŠEK, J. ROTTENBERG, R. KOSTŘICA, J. SROVNAL, M. HAJDÚCH, J. DRÁBEK, J. KLOZAR a R. CERVENA. Sledování mutace KRAS při léčbě cetuximabem u spinocelulárních karcinomů hlavy a krku. Remedia. 2012, 22(3), 231-234. ISSN 0862-8947.
KOUDELÁKOVÁ, V., M. KNEBLOVÁ a M. HAJDÚCH. Personalizovaná medicína a biomarkery v onkologii. Klinická farmakologie a farmacie. 2012, 26(4), 181-185. ISSN 1212-7973.
BENEDÍKOVÁ, A., J. SROVNAL, M. SZKORUPA, P. SKALICKÝ, J. CHUDÁČEK, T. BOHANES, J. ŠKARDA, Z. KOLÁŘ, M. HAJDÚCH a J. KLEIN. Biomarkery detekce minimální systémové diseminace u nemocných s karcinomem plic. Rozhledy v chirurgii. 2012, 91(4), 209-215. ISSN 0035-9531.
DUBSKA, L., M. VYSKOCILOVA, R. NENUTIL, D. VALIK, D. KNOFLICKOVA, P. FABIAN, I. KOCAKOVA, R. DEMLOVA, M. BERANEK, M. DRASTIKOVA, H. VOSMIKOVA, A. BODAY, K.. HORKA, J. SIMOVA, J. DRÁBEK, J. EHRMANN, M. HAJDÚCH, M. MATEJCKOVA, R. SIMA, D. TVRDIK, C. POVYSIL a A. RYSKA. Vyšetření mutačního statutu genu KRAS jako součást algoritmu léčby metastatického kolorektálního karcinomu. Časopis lékařů českých. 2011, 150(6), 321-326. ISSN 0008-7335.
DRÁBEK, J. a R. BRDICKA. Principy pro zachazeni s lidskym genetickym materialem a genotypizacni informaci. Časopis lékařů českých. 2010, 151(11), 507-513. ISSN 0008-7335.
HRABALEK, L., O. KALITA, H. ŠTUDENTOVÁ, J. JANKOVA, J. EHRMANN, R. TROJANEC a M. HAJDÚCH. Intramedullary spinal cord and cauda equina metastasis of breast carcinoma: case report. Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czech Republic. 2010, 154, 1-3. ISSN 1213-8118.

Books

DE SANCTIS, J.B., M. GIERA a D. RADZIOCH. Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases. 1. vyd. Lausanne: Frontiers Media SA, 2021. 120 s. ISBN: 978-2-88966-989-9.
BOUCHALOVA, K., M. HAJDUCH, J. BOUCHAL, A. HLOBILKOVA, M. HOUDOVA MEGOVA , M. HUDCOVA, V. KOUDELAKOVA, J. MEDALOVA, J. SROVNAL a R. TROJANEC. Prediktivní a prognostická onkologie. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2016. 122 s. ISBN: 978-80-244-3188-8.
DRABEK, J., J. BERKOVCOVA, P. DŽUBAK, M. HAJDUCH, M. KHOYLOU, V. KOUDELAKOVA, J. SROVNAL, M. STAŇKOVA a R. TROJANEC. Detekce nádorových biomarkerů v molekulárně biologické laboratoři. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2012. 144 s. ISBN: 978-80-244-3002-7.
HAJDUCH, M., J. DRABEK a R. TROJANEC. Biologická léčiva: Teoretické základy a klinická praxe. 1. vyd. Praha: Grada Publishing, 2012. 219 s. ISBN: 978-80-247-3727-0.
DRABEK, J. Interpretace DNA profilu pri urcovani otcovstvi a pribuznosti. 1. vyd. Brno: Tribun EU, s.r.o., 2011. 95 s. ISBN: 978-80-263-0066-3.

Book chapters

MIJARES, M., G. MARTINEZ a J.B. DE SANCTIS. Kauranes as Anti-inflammatory and Immunomodulatory Agents: An Overview of In Vitro and In Vivo Effects. In: Plant Secondary Metabolites Physico-Chemical Properties and Therapeutic Applications. 1.vyd. Singapore: Springer, 2022. Kapitola 7, s. 191-239. ISBN: 978-981-16-4778-9.
POLISHCHUK, P. Multi-instance Learning for Structure-Activity Modeling for Molecular Properties. In: Analysis of Images, Social Networks and Texts. 1.vyd. Kazan: Springer, 2021. Kapitola 7, s. 62-71. ISBN: 978-3-030-39574-2.
SROVNAL, J. Elektrochemické metody, (bio)senzory a čipové platformy. In: Principy a využití vybraných analytických metod v laboratorní medicíne. 1.vyd., korigovaný dotisk. Olomouc: Univerzita Palackého v Olonouci, 2021. Kapitola 2.3, s. 43-52. ISBN: 978-80-244-3951-8.
MIJARES, M., G. MARTINEZ a J.B. DE SANCTIS. Kauranes as Anti-inflammatory and Immunomodulatory Agents: An Overview of In Vitro and In Vivo Effects. In: Plant Secondary Metabolites Physico-Chemical Properties and Therapeutic Applications . 1.vyd. Singapore: Spinger Velar 2021, 2021. Kapitola 7, s. ?. ISBN: 978-981-16-4778-9.
DE SANCTIS, J.B. Pharmacologic Modulation of the Immune Response Against Tumours in the Elderly . In: Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models. 1.vyd. Singapore: Springer Verlag, 2020. Kapitola 8, s. 157-164. ISBN: 978-981-15-7585-3.
TINKOV, O., P. POLISHCHUK, V. GRIGOREV a Y. POROZOV. The Cross-Interpretation of QSAR Toxicological Models. In: ISBRA 2020: Bioinformatics Research and Applications. 1.vyd.. x: Springer, Cham, 2020. Kapitola x, s. 262-273. ISBN: 978-3-030-57820-6.
KOUDELÁKOVÁ, V. a M. HAJDÚCH. Predictive Cancer Biomarkers: Current Practice and Future Challenges. In: Handbook of Biomarkers and Precision Medicine. 1.vyd. Boca Raton: CRC Press, 2019. Kapitola 7.5, s. 383-394. ISBN: 978-1-4987-6258-8 .
POLISHCHUK, P., E. MOKSHYNA, A. KOSINSKAYA, A. MUATS, M. KULINSKY, O. TINKOV, L. OGNICHENKO, T. KHRISTOVA, A. ARTEMENKO a V. KUZMIN. Structural, Physicochemical and Stereochemical Interpretation of QSAR Models Based on Simplex Representation of Molecular Structure. In: Advances in QSAR Modeling: Applications in Pharmaceutical, Chemical, Food, Agricultural and Environmental Sciences. 1st. -: Springer International Publishing, 2018. Kapitola 4, s. 107-147. ISBN: 978-3-319-56849-2.
SROVNAL, J. Onkogenetika. In: Základy lékařské genetiky pro studující všeobecného lékařství. 1.vyd.. Olomouc: Univerzita Palackého v Olomouci, 2018. Kapitola x, s. 109-116. ISBN: 978-80-244-5368-2.
LIGASOVÁ, A. a K. KOBERNA. Tracking Mitochondrial DNA In Situ. In: Methods in molecular biology . 3. vyd. United States: Clifton, N.J.: Humana Press, 2016. Kapitola 7, s. 81-92. ISBN: 978-1-4939-3039-5.
DŽUBÁK, P., M. URBAN a M. HAJDÚCH. Vývoj nových léčiv. In: Molekulární medicína. 1. vyd. Praha: Galén, 2015. Kapitola 11, s. 469-472. ISBN: 978-80-7492-121-6.
CMARKO, D., A. LIGASOVÁ a K. KOBERNA. Tracking DNA and RNA sequences at high resolution. In: Electron Microscopy Methods in Molecular Biology. 3. vyd. New York: Humana Press, 2014. Kapitola 16, s. 343-366. ISBN: 978-1-62703-775-4.
CIBIČEK, N., J. VACEK, M. BERANEK, P. DŽUBÁK, Z. HEŘMANOVÁ, P. KOSINA, M. KUBALA, M. NOVÁK, B. PAPOUSKOVA, J. SROVNAL, J. VÁVROVÁ, J. VOSTALOVA, M. ZATLOUKALOVA a H. ŽIVNÁ. Hmotnostní spektrometrie. In: Principy a využití vybraných analytických metod v laboratorní medicíně. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2014. Kapitola 2.2, s. 34-40. ISBN: 978-80-244-3951-8.
CIBIČEK, N., J. VACEK, M. BERANEK, P. DŽUBÁK, Z. HEŘMANOVÁ, P. KOSINA, M. KUBALA, M. NOVÁK, B. PAPOUSKOVA, J. SROVNAL, J. VÁVROVÁ, J. VOSTALOVA, M. ZATLOUKALOVA a H. ŽIVNÁ. Elektrochemické metody, (bio)senzory a čipové platformy. In: Principy a využití vybraných analytických metod v laboratorní medicíně. 1. vyd. Olomouc: Univerzita Palackého v Olomouci, 2014. Kapitola 2.3, s. 43-44. ISBN: 978-80-244-3951-8.
ŠÁNA, J., M. HAJDÚCH a O. SLABÝ. MicroRNA and Glial tumors: Tiny Relation with Great Potential. In: Novel Therapeutics Concepts in Targeting Glioma. 1. vyd. Rijeka: InTech, 2012. Kapitola 4, s. 59-74. ISBN: 979-953-307-198-4.
HAJDÚCH, M., J. DRÁBEK a R. TROJANEC. Význam biomarkerů pro indikaci cílené biologické léčby v onkologii. In: Biologická léčiva: Teoretické základy a klinická praxe. 1. vyd. Praha: Grada Publishing, 2012. Kapitola 2.8, s. 137-149. ISBN: 978-80-247-3727-0.
HAJDÚCH, M. a R. PYTLÍK. Biologická léčba v onkologii. In: Biologická léčiva: Teoretické základy a klinická praxe. 1. vyd. Praha: Grada Publishing, 2012. Kapitola 2.7, s. 111-137. ISBN: 978-80-247-3727-0.
DRÁBEK, J. Design primerů pro polymerázovou řetězovou reakci (PCR). In: Detekce nádorových biomarkerů v molekulárně biologické laboratoři. 1.vyd. Olomouc: Univerzita Palackeho v Olomouci, 2012. Kapitola 5, s. 45-56. ISBN: 978-80-244-3199-4.
ŠAREK, J., M. KVASNICA, M. VLK, M. URBAN, P. DŽUBÁK a M. HAJDÚCH. The Potential of Triterpenoids in the Treatment of Melanoma. In: Research on Melanoma – A Glimpse into Current Directions and Future Trends. 1.vyd. Rijeka: InTech, 2011. Kapitola 7, s. 125-158. ISBN: 978-953-307-293-7.

Patents

  1. Published Application PCT/CZ2016/050021 under WO 2018/001393 (4.1.2018)
  2. Patent: EP 3478701; Granted: 10.8.2022; Ownership: Institute of Organic Chemistry and Biochemistry CAS, Prague; Palacký University, Olomouc; Inventors: Hocek Michal, Tichý Michal, Hajdúch MariánDžubák Petr
  3. Patent: US 10,414,788; Granted: 17.9.2019; Ownership: Institute of Organic Chemistry and Biochemistry CAS, Prague; Palacký University, Olomouc; Inventors: Hocek Michal, Tichý Michal, Hajdúch Marián, Džubák Petr
  4. Patent: JP 6650074; Granted: 21.1.2020;  Ownership: Institute of Organic Chemistry and Biochemistry CAS, Prague; Palacký University, Olomouc; Inventors: Hocek Michal, Tichý Michal, Hajdúch MariánDžubák Petr
  5. Patent: CA 3.029.170; Granted: 16.2.2021; Ownership: Institute of Organic Chemistry and Biochemistry CAS, Palacky University, Olomouc; Inventors: Hocek Michal, Tichý Michal, Hajdúch Marián, Džubák Petr

Status: Terminated

Patent: CZ 307 807; Granted: 10.4.2019; Ownership: Palacky University, Olomouc; Inventors: Koberna KarelLigasová Anna

Status: Terminated

Project: Bioinformatics processing of big data within clinical and preclinical studies
Supervisors: Hajdúch Marián M.D., Ph.D., Pavliš Petr Ph.D.
Available: 3
Intended for: Doctoral training
Summary:

3 places in full-time or combined form of study

Project: Drug development of small molecules
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

2 places in full-time study

Project: New prognostic and predictive factors in solid tumors
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 3
Intended for: Doctoral training
Summary:

3 places in full-time or combined form of study

Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Slavkovský Rastislav Ph.D., Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 3
Intended for: Doctoral training
Summary:

3 places in full-time study

Project: Development of 3D pharmacophore signatures and their application in the design of anticancer drugs
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary:

1 place in the face-to-face form of study

Project: Identification of proteomic biomarkers in exhaled air condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

2 places in full-time study

Project: The role of tumor hypoxia in the development of acquired resistance to microtubule-targeted drugs
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

1 place in full-time study

Project: Search and characterization of substances for the therapy of congenital or acquired diseases caused by aberrant splicing of pre-mRNA
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

1 place in full-time study

Project: Drug repurposing for treatment and prevention of diseases
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

1 place in full-time study

Project: Identification of molecular targets and mechanisms of resistance in antitumor drugs using cell biology and proteomics methods
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

2 places in full-time study

Project: Antitumor drugs targeting nucleic acid metabolism
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

2 places in full-time study

Project: Diagnostics and therapy of rare diseases
Supervisors: Hajdúch Marián M.D., Ph.D., Srovnal Josef M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

2 places in full-time study

Project: Genetic and epigenetic biomarkers of cancer diseases
Supervisors: Drábek Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

1 place in full-time study

Project: Physiology and pathophysiology of aging
Supervisors: Hajdúch Marián M.D., Ph.D., Voller Jiří Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

2 places in full-time study

Project: Identification of proteomic biomarkers in exhaled breath condensate in patients with systemic or pulmonary disease
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

Ph.D. topic is focused on the identification of biomarkers of lung diseases by means of a non-invasive collection of exhaled breath condensate. The project will monitor the presence of proteins in exhaled air in various diseases such as asthma, cystic fibrosis, lung tumors, or some infectious diseases, as well as quantitative changes of these proteins compared to a healthy population. Changes in these potential biomarkers with respect to therapeutic response and disease progression will be evaluated and validated.

Project: Genetic and epigenetic biomarkers in cancer
Supervisors: Drábek Jiří Ph.D., Slavkovský Rastislav Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 3
Intended for: Doctoral training
Summary:

Clonal hematopoiesis of indeterminate potential (CHIP) has recently been described as a common phenomenon associated with aging. It is characterized by the accumulation of somatic mutations in cells of the hematopoietic system. Although CHIP is manifested by the expansion of certain cell clones, this condition is not accompanied by any morphological features of hematological neoplasia. However, it has been shown that the incidence of clonal hematopoiesis correlates with increased overall mortality and the risk of developing malignant transformation of hematopoietic cells as well as cardiovascular disease, such as ischemic stroke. To what extent and by what mechanisms clonal hematopoiesis contributes to disease development remains a question of current research. The main aim of the project will be to pinpoint the principal cells carrying CHIP somatic mutations, and to study their role in development and maintenance of atherosclerotic plaques, especially of those involved in development of stroke. The comparison of the phenotype of CHIP positive and negative cells will be of special interest. The use of cellular models not only include different types of leucocytes but circulatory progenitor endothelial cells as well. The study will involve elderly subjects with the positive presence of CHIP (>65 years). Subject will be characterized based on the presence or absence of ischemic stroke and the presence or absence of carotid stenosis by our clinical collaborators. The presence of somatic variants in 38 selected genes associated with CHIP will be tested in subjects of interest within our research group. The project will use various techiques including FACS, MACS, cell cultures, DNA isolation from small amount of cells, a highly sensitive sequencing method for DNA genotyping allowing detection of variant with less than 1% allelic frequency, DNA/RNA sequencing library preparation, deep massively parallel sequencing of panel of genes using unique molecular barcodes/indices, RNAseq, bioinformatics and data analysis with possibilities of calculations using high performance computing cluster, data management and statistical evaluation.

Project: Identification of novel proteomic cancer biomarkers
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Project: New prognostic and predictive factors in solid tumors
Supervisors: Srovnal Josef M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

Cancer is the second leading cause of death in the western countries. Early diagnosis and targeted therapy improve the therapeutic outcome. With the emergence of new biotechnologies, diagnosis can be made early and precisely, and the knowledge of tumor molecular genetics can identify the most appropriate therapy for a particular patient. The sensitivity of modern molecular methods makes it possible to characterize the tumor properties from sites remote from the primary tumor using patient's blood. The subject of the offered study program is the identification of new prognostic and predictive biomarkers of cancer using liquid biopsies. This is particularly the analysis of circulating tumor cells (CTCs), circulating free tumor DNA (ctDNA) and circulating miRNAs. The aim of the project is to further implement a liquid biopsy concept into the diagnosis and therapy monitoring of solid tumors, especially colorectal, breast, lung and CNS tumors. These include therapy response and resistance monitoring, identifying new therapeutic targets and estimating disease prognosis. The project will provide training in widely-used, transferable techniques, including circulation tumor cells capture system, digital droplet PCR, reverse-transcription qPCR, RNA-seq, single cell analyses, xenografts models and other multi-omics methods. We are looking for candidates with a background in Molecular Biology, Medicine, Cell Biology or a related area, who are enthusiastic about investigating novel approaches in cancer diagnostic that have significant potential for public health.

Project: In silico design of compounds with desired properties
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 2
Intended for: Doctoral training
Summary:

One of the main goals of chemoinformatics is development of new compounds with desired properties or activities. Many de novo design approaches were suggested so far. The designed compounds should satisfy multiple criteria, e.g. synthetic accessibility, novelty, diversity, selectivity, etc. Generators of chemical structures satisfying these criteria are a core of all de novo design approaches. Available approaches often result in synthetically hardly accessible structures or limit their diversity and novelty. Within this study a new fragment-based approach for structure generation will be implemented which will result in chemically valid structures and will provide flexible control over their diversity, novelty and synthetic accessibility. This will be used for development of de novo design approaches based on molecular docking, pharmacophore modeling to generate compounds which will be able to fit to a binding site of a given protein. This can be used for development of novel compounds and for optimization of structures of available ligands. Developed approaches should be implemented in open-source software tools.

Project: Development of 3D pharmacophore signatures and their applications to drug design
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Doctoral training
Summary:

Pharmacophore modeling is a powerful approach to encode possible protein-ligand interactions and searching of new promising compounds in large libraries. So far, almost all available software for pharmacophore modeling is proprietary and implemented approaches have some limitations to efficiently work with big data. Within this study a new approach to represent 3D pharmacophores as hashes will be implemented. This representation will make it possible to quickly identify similar pharmacophores in large data sets. This property can be used to develop a new alignment free approach to ligand-based pharmacophore modeling. The developed 3D pharmacophore hashes will help to identify representative pharmacophores retrieved from molecular dynamic simulation of protein-ligand complexes. These developments will increase success rates of future screening campaigns and should be implemented in open-source software.

Project: Bio- and cheminformatics in biology of aging
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

Although hundreds of biological databases are available, a richly annotated database of anti-aging compounds with diverse mechanisms of action has been missing. The aim of the project is to create a database of compounds with anti-aging activity that would offer a rich annotation of both compound and involved biological mechanisms. The data will be collected from a wide range of public databases, by text-mining of scientific literature and patents as well as from results of in-house high-throughput screening. The data will be used for formulation of new hypotheses of mechanisms of aging as well as for identification of novel anti-aging compounds.

Project: Identification of pro-longevity pathways and mechanisms of model organisms
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

The aim of the project is to identify the novel compounds which can increase life-span of C. elegans, increase their resistance against stress and neurodegeneration, using high-throughput and high-content screening platforms. Active compounds will be further studied in human cell cultures. Mechanisms of action of interesting hits will be studied by OMICS

Project: Drug resistance mechanisms in cancer
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

Mechanisms of tumor cell resistance to newly developed and existing nucleoside analog cytostatics will be studied. These drugs are used in most anti-cancer therapy protocols and the emergence of drug resistance is a major problem in the treatment of cancer patients. Resistant cell lines prepared in the past will be studied to identify the key mechanisms of resistance, which will be carried out by their detailed characterization using cell biology, but also proteomics and molecular genetics. The significance of the identified changes will be further verified on clinical material and will be applied in the development of new anticancer drugs from this class.

Project: Biology of aging and DNA damage
Supervisors: Hajdúch Marián M.D., Ph.D.
Available: 1
Intended for: Doctoral training
Project: Pathological conditions associated with human papillomavirus infection
Supervisors: Koudeláková Vladimíra PhD., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

High-risk human papillomavirus infection (HPV infection) is associated with several cancers such as cervical, vaginal, vulvar, head and neck, anal, and penile carcinomas. Nearly all cervical cancers are caused by HPV infection. Despite available vaccination and cervical cancer screening program, cervical cancer is one of the most common types of cancer affecting women worldwide. Main problems of cervical cancer screening are low participation rate and low sensitivity of cytology which is still used in the majority of cervical cancer screening programs. Solution could be the transition to primary HPV screening and the sending of self-sampling devices to cervical cancer screening non-attenders. The best strategy for enrolling Czech women in the screening program will be analysed during this project. Obtained samples will be tested for the presence of HPV DNA and the presence of other molecular biomarkers important in viral clearance and cervical cancer progression/regression. Discoveries will lead to identification of biomarkers for early diagnosis, disease progression or triage strategies. The aim of the project is to clarify the best strategy for enrolling women who do not attend cervical cancer screening program. The second aim is to study genetic and proteomic profile of HPV positive/negative women with normal/abnormal cervical cytology as well as genetic variants of HPV and its importance for regression/progression of the disease. Skills to be taught include biochemistry, molecular biology, bioinformatics and cell culture. This is an ideal project for a student who wishes to pursue higher studies in cancer research. The project will use various techniques including PCR, in situ hybridization, next generation sequencing, mass spectrometry.

Project: Identification of molecular targets of anticancer therapy applying cell biology and proteomics tools
Supervisors: Džubák Petr M.D., Ph.D., Hajdúch Marián M.D., Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

Selected, highly active derivatives of triterpenes, chelators and nucleosides will be studied with a view to identify the mechanisms of their antitumor effects. Advanced methods of cell biology, proteomics and genomics such as affinity purification of protein targets, CETSA and others will be used for their study. The identified targets will be validated in relation to their clinical relevance in anticancer therapy.

Project: An extensive structural and biochemical characterization of tau oligomeric species in Alzheimer’s disease and other tauopathies
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

An extensive structural and biochemical characterization of tau oligomeric species in Alzheimer’s disease and other tauopathies

Project: The role of tumor hypoxia in the acquisition of resistance to microtubule-targeting drugs
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

Hypoxia is one of the major factors causing resistance to microtubule-stabilizing drugs (MSDs) and other non-microtubule drugs used in chemotherapy. Hypoxia results in changes in tubulin conformation, expression of tubulin isotypes and metabolic pathways that make cancer cells less susceptible to paclitaxel, a taxane used extensively in the treatment of solid tumors. Recent cellular studies have shown that non-taxane MSDs with a similar mode of microtubule stabilization to paclitaxel is more effective in hypoxic cancer cells than paclitaxel. Due to a different microtubule-binding site, we hypothesize that non-taxane MSDs may have a better cytotoxic effect in cancer cells under hypoxia. The goal of this project is to study the anti-cancer effect of non-taxane MSDs in hypoxic ovarian and cervical cancer cell models.

Project: A combination of 2D and 3D cell cultures for a smart and effective identification and characterization of anti-hypoxic candidates
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

Hypoxia is a prominent feature of different solid tumor types. A central component of hypoxic adaptation is the stabilization of hypoxia-inducible factor-1 (HIF-1), a key transcriptional regulator of hypoxia that orchestrates the transcriptional regulation of genes involved in a plethora of cellular processes. Considering the multiple roles of HIF-1 in cancer, interest in novel small-molecule inhibitors of the HIF-1 pathway has steadily increased over the past 10 years. However, despite extensive research, no specific inhibitor of HIF-1 has been brought to the market, making the field still ripe for further exploration. The goal of the present work is to utilize the potential of a combination of 2D and 3D cellular models for identification and characterization of inhibitors of HIF-1 and/or HIF-1 pathway by screening in 2D cultures, and lightsheet microscopy and mass spectrometry studies in spheroid cultures.

Project: Pharmacokinetic methods in preclinical drug testing
Supervisors: Hajdúch Marián M.D., Ph.D., Lišková Barbora Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

The study of ADME properties of a potential drug that are part of the IMTM chemical library - obtained by national or international cooperation belongs to one of the first steps in predicting potential drugs. In vitro models generate many ADME parameters, including chemical, plasma and microsomal stability, plasma protein binding and proportion of passive diffusion as a transport mechanism. The Caco-2 and MDCK-MDR1 permeability assays are established models of intestinal and blood-brain barriers, respectively. Analysis of samples is performed using a Agilent RapidFire 300 - rapid online solid phase extraction with subsequent detection of the mass spectrometer Qtrap 5500 (AB Sciex) - RF/MS. High-Throughput Mass Spectrometry System RF/MS delivers ultrafast, label – free analysis of native compounds for biochemical assays in ADME and provide throughput speeds of 6 to 10 seconds per sample.

Project: Screening and characterization of compounds for therapy of diseases caused by aberrant pre-mRNA splicing
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

Recently, we identified several novel modulators of alternative splicing with the ability to increase expression of wild-type transcripts of several genes relevant for neurodegeneration or cancer. However, mechanisms of action of those promising compounds remains unclear. The aim of the project is to (i) identify molecular targets and relevant pathways, (ii) design assays for high-througput screening of a library of chemical compounds, and (iii) to identify novel structural types of active compounds.

Project: Screening and characterization of compounds for therapy of mitochondrial and metabolic disorders
Supervisors: Voller Jiří Ph.D.
Available: 1
Intended for: Doctoral training
Summary:

Pharmacotherapy of hereditary mitochondrial diseases including neurodegenerations and cardiopathies is only symptomatical at present. The aim of this study is to identify the novel candidate drugs by high-throughput screening using patient-derived cell lines. The assays will evaluate survival under metabolic and oxidative stress as well as morphology and function of mitochondria. Mechanism of action of promising compounds will be studied by OMICS methods.

Project: Multimodal imaging methods for testing bioactive molecules in vivo
Supervisors: Petřík Miloš Ph.D., Nový Zbyněk Ph.D.
Available: 2
Intended for: Doctoral training
Summary:

The student will employ modern in vivo imaging techniques namely positron emission tomography, single-photon emission tomography, computed tomography and optical imaging in order to elucidate effect of novel anticancer or antimicrobial agents. The other part of the project will be assessment of novel radiotracers directed towards targets expressed by tumour cells or by microbial pathogens. Daily work routine will include all proper working steps common in radiopharmacy, i.e. starting with gaining an radioisotope from dedicated source, radiolabelling of selected compound, quality control (HPLC/TLC), stability tests, in vitro testing of biological properties and finally in vivo procedures (biodistribution, static/dynamic imaging). Expected previous education includes medicine, pharmacy, pharmacology or related field.

Project: In vivo imaging of 68Ga labelled biomolecules
Supervisors: Petřík Miloš Ph.D.
Available: 1
Intended for: Bachelor training
Project: Computationally guided optimization of compound properties
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Master training
Project: Fragment-based de novo design using pharmacophore models
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Master training
Project: Radiolabelled peptides for cancer imaging
Supervisors: Petřík Miloš Ph.D.
Available: 1
Intended for: Master training
Project: Genetic biomarkers
Supervisors: Drábek Jiří Ph.D.
Available: 1
Intended for: Master training
Project: Development of organoid assays for anti-tumour drug screening
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Bachelor training, Master training
Project: Epigenetic biomarkers
Supervisors: Drábek Jiří Ph.D.
Available: 1
Intended for: Master training
Project: Drug synergy studies in 3D spheroids cultures of tumour cell lines
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Bachelor training, Master training
Project: Novel 3D pharmacophore representation for machine learning
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Master training
Project: Biochemical and cellular analysis of amyloid staining agents in models of tauopathies and synucleopathies
Supervisors: Das Viswanath M.Sc., Ph.D.
Available: 2
Intended for: Bachelor training, Master training
Project: Small animal imaging using microPET/SPECT/CT system in preclinical developement of potential drugs
Supervisors: Nový Zbyněk Ph.D.
Available: 1
Intended for: Bachelor training, Master training
Project: Radiolabelled siderophores for infection imaging
Supervisors: Petřík Miloš Ph.D.
Available: 1
Intended for: Master training
Project: Applicability domains in machine learning modeling
Supervisors: Polishchuk Pavlo Ph.D., M.Sc.
Available: 1
Intended for: Master training

Laboratory head

Hajdúch Marián M.D., Ph.D.

Research groups

Nanomaterials in medicine

Junior research group

Translational disease models and neurodegeneration

Junior research group

Oncogenetics and forensic genetics group

Senior research group

Virology and molecular carcinogenesis

Junior research group

Chemoinformatics and drug design

Senior research group

Genomics and circulating biomarkers

Senior research group

Imaging and Tracing

Senior research group

Molecular and personalized medicine

Senior research group