Imaging & Tracing

Group leader

Miloš Petřík

Members

Zbyněk Nový

Miroslav Popper

Technicians

Kateřina Frantíková

Tereza Schneiderová

 

Research

The Imaging & Tracing core works on the development of novel radiopharmaceuticals and molecular imaging agents. This includes the development of superior radiolabelling strategies and radioanalytics, in vitro and in vivo evaluation of novel tracer candidates using broad spectrum of imaging approaches. It also develops small animal models of various diseases, particularly for infection and cancer.

 

Highlights:

  • Preclinical development of novel radiopharmaceuticals
  • Radiometal labelling of bioactive molecules
  • Aspergillus and Pseudomonas infection imaging
  • Animal tumor models
  • Small animal imaging

 

Selected publications

KAEOPOOKUM, P., D. SUMMER, J. PFISTER, T. ORASCH, B. LECHNER, M. PETŘÍK, Z. NOVÝ, B. MATUSZCZAK, C. RANGGER, H. HAAS a C. DECRISTOFORO. Modifying the Siderophore Triacetylfusarinine C for Molecular Imaging of Fungal Infection. Molecular Imaging and Biology. 2019, 21(6), 1097-1106. ISSN 1536-1632. IF: 3.626. PMID: 30838551

PETŘÍK, M., E. UMLAUFOVÁ, V. RACLAVSKÝ, A. PALYZOVA, V. HAVLICEK, H. HAAS, Z. NOVÝ, D. DOLEŽAL, M. HAJDÚCH a C. DECRISTOFORO. Imaging of Pseudomonas aeruginosa infection with Ga-68 labelled pyoverdine for positron emission tomography. Scientific Reports. 2018, 8(1), 15698. ISSN 2045-2322 IF: 4.122. PMID: 30356077

SKRIBA, A., T. PLUHACEK, A. PALYZOVA, Z. NOVÝ, K. LEMR, M. HAJDÚCH, M. PETŘÍK a V. HAVLICEK. Early and Non-invasive Diagnosis of Aspergillosis Revealed by Infection Kinetics Monitored in a Rat Model. Frontiers in Microbiology. 2018, 9, 2356. ISSN 1664-302X. IF: 4.019. PMID: 30349512

HAAS, H., M. PETŘÍK a C. DECRISTOFORO. An iron-mimicking Trojan horse entering fungi - has the time come for molecular imaging of fungal infections? PLOS Pathogens. 2015, 11(1), 1-7. ISSN 1553-7366. IF: 7.003. PMID: 25634225

PETRIK, M., G. FRANSSEN, H. HAAS, P. LAVERMAN, C. HÖRTNAGL, M. SCHRETTL, A. HELBOK, C. LASS-FLÖRL a C. DECRISTOFORO. Preclinical evaluation of two 68Ga-siderophores as potential radiopharmaceuticals for Aspergillus fumigatus infection imaging. European Journal of Nuclear Medicine and Molecular Imaging. 2012, 39(7), 1175-1183. ISSN 1619-7070. IF (2011): 4.991 PMID: 22526953