Hradil Pavel

Hradil Pavel's picture

Publications (Impact Factor Journals):

  • [6]
    HRADIL, P., J. HLAVÁČ, M. SOURAL, M. HAJDÚCH, M. KOLÁŘ a R. VEČEŘOVÁ. 3-Hydroxy-2-phenyl-4(1H)-quinolinones as Promising Biologically Active Compounds. Mini-reviews in Medicinal Chemistry. 2009, 9(6), 696-702. ISSN 1389-5575. IF: 3.132. PMID: 19519495
  • [5]
    SPÁČILOVÁ, L., P. DŽUBÁK, M. HAJDÚCH, S. KŘUPKOVÁ, P. HRADIL a J. HLAVÁČ. Synthesis and cytotoxic activity of various 5-[alkoxy-(4-nitro-phenyl]-methyl]-uracils in their racemic form. Biorganic & Medicinal Chemistry Letters. 2007, 17(23), 6647-6650. ISSN 0960-894X. IF: 2.538. PMID: 17935983
  • [4]
    SOURAL, M., J. HLAVÁČ, P. HRADIL, I. FRYŠOVÁ, M. HAJDÚCH, V. BERTOLASI a M. MALOŇ. Synthesis and Cytotoxic Activity of Substituted 2-Phenyl-3-Hydroxy-4(1H)-Quinolinones-7- Carboxylic Acids and their Phenacyl Esters. European Journal of Medicinal Chemistry. 2006, 41(4), 467-474. ISSN 0223-5234. IF: 2.022. PMID: 16540209
  • [3]
    SOURAL, M., J. HLAVÁČ, P. HRADIL a M. HAJDÚCH. Efficient Synthesis and Cytotoxic Activity of Some Symmetrical Disulfides Derived from the Quinolin-4(1H)-one Skeleton. European Journal of Organic Chemistry. 2009, -(23), 3867-3870. ISSN 1434-193X. IF: 3.016.
  • [2]
    HORÁK, R., L. KVAPIL, K. MOTYKA, L. SLANINOVÁ, M. GREPL, K. KOTISEK, M. URBASEK, P. HRADIL a M. SOURAL. Synthesis of 2-alkenyl-3-hydroxyquinolin-4(1H)-ones as promising antimicrobial and fluorescent agents. Tetrahedron. 2018, 74(74), 366-374. ISSN 0040-4020. IF: 2.651.
  • [1]
    SAMSULOVA, V., M. POLÁKOVÁ, R. HORÁK, M. SEDIVA, L. KVAPIL a P. HRADIL. Synthetic approach to novel glycosyltriazole-3-hydroxyquinolone conjugates and their antimicrobial properties. Journal of Molecular Structure. 2019, 1177, 16-25. ISSN 0022-2860. IF: 2.011.

Patents, Utility models & other IP's :

[4] 2-PHENYL-3-HYDROXYQUINOLIN-4(1H)-ONE-8-CARBOXAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE, Priority Appl. CZ PV 2010-476
  1. Patent: CZ 304 527, Granted: 7. 5. 2014, Ownership: Palacky University Olomouc, Inventors: Soural Miroslav, Hlaváč Jan, Hradil Pavel

Status: Terminated

[3] EFFICIENT METHOD OF BIOTINYLATION OF AMINO COMPOUNDS USING SOLID PHASE SYNTHESIS FOR AFFINITY CHROMATOGRAPHY NEEDS, Priority Appl. CZ PV 2010-229
  1. Patent: CZ 302 669, Granted: 13. 7. 2011, Ownership: Palacky University in Olomouc, Inventors: Soural MiroslavHlaváč JanHradil Pavel

Status: Terminated

[2] EFFICIENT METHOD OF BIOTINYLATION OF COMPOUNDS CONTAINING CARBOXYL GROUP USING SOLID PHASE SYNTHESIS FOR AFFINITY CHROMATOGRAPHY NEEDS, Priority Appl. CZ PV 2010-230
  1. Patent: CZ 302 510, Granted: 11. 5. 2011, Ownership: Palacky University Olomouc, Inventors:Soural Miroslav, Hlaváč Jan, Hradil Pavel

Status: Terminated

[1] DERIVATES OF 2-PHENYL-3-HYDROXYQUINOLINE-4(1H)-ONE AND METHODS OF THEIR PREPARATION AND UTILIZATION, Priority Appl. CZ PV 2006-546
  1. Patent: CZ 300 589, Granted: 13. 5. 2009, Ownership: Palacky University Olomouc, Inventors: Krejčí Petr, Hlaváč Jan, Hradil Pavel, Hajdúch Marián
  2. Patent: US 8,299,092, Granted: 30. 10. 2012, Ownership: Palacky University Olomouc, Inventors: Krejčí Petr, Hlaváč Jan, Hradil Pavel, Hajdúch Marián
  3. Patent: EP 2 064 200, Granted: 4. 9. 2013, Ownership: Palacky University Olomouc, Inventors: Krejčí Petr, Hlaváč Jan, Hradil Pavel, Hajdúch Marián

Status: Terminated


Doctoral students mentor:

[2] Marie Boháčová, Synthesis of new biologically active substances from the group of 2-substituted 3-hydroxy-4 (1H) -quinolones,
Ph.D. specialization: , status: Ongoing, from: 2014
[1] Radim Horák, Synthesis of 2-alkyl-3-hydroxyquinoline-4 (1H) -one,
Ph.D. specialization: , status: Ongoing, from: 2013