Mádrová Lucie M.Sc
Phone: +420 585632176
Study of the effect of selected cancerostatics on the cell metabolome
The thesis is focused on the development of both targeted and untargeted metabolomics methods (liquid chromatography coupled with high resolution mass spectrometry) for the study of the effects of various anticancer drugs on model cell lines. The main goal is to quantitatively analyse changes in metabolome’s composition for the comprehensive characterization of metabolic networks.
Supervisor:Adam Tomáš Ph.D.
Status:Ongoing 2015 - 2015
Publications (Impact Factor Journals):
- VÁCLAVÍK, J., K. COENE, I. VROBEL, L. NAJDEKR, D. FRIEDECKÝ, R. KARLÍKOVÁ, L. MÁDROVÁ, A. PETSALO, U. ENGELKE, A. VAN WEGBERG, L. KLUIJTMANS, T. ADAM a R. WEVERS. Structural elucidation of novel biomarkers of known metabolic disorders based on multistage fragmentation mass spectra. Journal of Inherited Metabolic Disease. 2017, -, -. ISSN 0141-8955. IF: 3.970. PMID: 29139026